Blueprints for green biotech: development and application of standards for plant synthetic biology.

Blueprints for green biotech: development and application of standards for plant synthetic biology.

Synthetic biology goals to use engineering ideas to the design and modification of organic programs and to the development of organic components and gadgets. The capacity to programme cells by offering new directions written in DNA is a foundational know-how of the sphere. Large-scale de novo DNA synthesis has accelerated synthetic biology by providing custom-made molecules at ever lowering prices. However, for massive fragments and for experiments during which libraries of DNA sequences are assembled in several mixtures, meeting within the laboratory continues to be fascinating.

Biological meeting standards permit DNA components, even these from a number of laboratories and experiments, to be assembled collectively utilizing the identical reagents and protocols. The adoption of such standards for plant synthetic biology has been cohesive for the plant science neighborhood, facilitating the application of genome enhancing applied sciences to plant programs and streamlining progress in large-scale, multi-laboratory bioengineering initiatives. This perspective will display the shift that biotech/pharma is already making and will suggest that the trade has a chance to compel change by adopting some points of the tech trade on the subject of fashions for know-how/product development and management attributes.

Subjects had been divided into 4 teams: Group 1 included 140 diabetic and non-diabetic topics with regular urea and haemoglobin ranges; Group 2 included 84 diabetic and non-diabetic topics with excessive urea ranges; Group three included 44 diabetic and non-diabetic topics with iron deficiency anaemia; and Group four included 52 diabetic and non-diabetic topics with excessive haemoglobin ranges. EP Evaluator Release eight program was used to guage the resultant information. The biotech and pharma (biotech/pharma) trade is in dire want of discovering methods to extend efficacy, effectivity, and affordability of its merchandise. The info and know-how trade (“tech”) trade, which is an trade equally based on innovations and innovation, might present some meals for thought.

 Blueprints for green biotech: development and application of standards for plant synthetic biology.

RABiT-II: Implementation of a High-Throughput Micronucleus Biodosimetry Assay on Commercial Biotech Robotic Systems.

We display the use of high-throughput biodosimetry platforms primarily based on industrial high-throughput/high-content screening robotic programs. The cytokinesis-block micronucleus (CBMN) assay, utilizing solely 20 μl complete blood from a fingerstick, was applied on a PerkinElmer cell::explorer and General Electric IN Cell Analyzer 2000. On common 500 binucleated cells per pattern had been detected by our FluorQuantMN software program. A calibration curve was generated within the radiation dose vary as much as 5.0 Gy utilizing the information from eight donors and 48,083 binucleated cells in complete.
The research described right here demonstrates that high-throughput radiation biodosimetry is sensible utilizing present industrial high-throughput/high-content screening robotic programs, which may be readily programmed to carry out and analyze robotics-optimized cytogenetic assays. Application to different industrial high-throughput/high-content screening programs past those used on this research is clearly sensible. This method will permit a lot wider entry to high-throughput biodosimetric screening for large-scale radiological incidents than is at present accessible.
Keep up with at the moment’s single-use know-how customary but in addition stay one step forward” – that would have been the motto of the BioTech 2016 convention at ZHAW Waedenswil on September 5 and 6, which introduced collectively producers, suppliers, customers, regulatory specialists and representatives of organizations on this discipline to implement single-use gadgets everywhere in the world. It was an effectiveness evaluation of the pattern to exchange reusable gear in manufacturing amenities with single-use elements.
Most of the genetically modified (GM) crops at present commercialized embody a handful of crop species (soybean, corn, cotton and canola) with agronomic characters (traits) directed in opposition to some biotic stresses (pest resistance, herbicide tolerance or each) and created by multinational corporations. The identical crops with agronomic traits already available on the market at the moment will proceed to be commercialized, however there can be additionally a wider vary of species with mixed traits.
The timeframe anticipated for market launch of the following biotech crops is not going to solely depend upon science progress in analysis and development (R&D) in laboratories and fields, but in addition totally on how demanding regulatory necessities are in international locations the place advertising and marketing approvals are pending. Regulatory constraints, together with environmental and well being impression assessments, have elevated considerably previously a long time, delaying approvals and rising their prices. This has generally discouraged public analysis entities and small and medium measurement plant breeding corporations from utilizing biotechnology and given desire to different applied sciences, not as stringently regulated.
Nevertheless, R&D applications are flourishing in growing international locations, boosted by the need to satisfy the worldwide challenges which are meals safety of a booming world inhabitants whereas mitigating local weather change impacts. Biotechnology is an instrument on the service of these imperatives and all kinds of crops are at present examined for their excessive yield regardless of biotic and abiotic stresses. Many crops with greater water or nitrogen use effectivity, tolerant to chilly, salinity or water submergence are being developed. Food safety is just not solely a query of amount but in addition of high quality of agricultural and meals merchandise, to be accessible and accessible for those who want it probably the most.
Many biotech crops (particularly staple meals) are subsequently being developed with dietary traits, akin to biofortification in nutritional vitamins and metals. The principal worldwide seed corporations proceed to be the most important buyers in plant biotechnology R&D, and usually collaborate within the growing world with public establishments, personal entities and philanthropic organizations. These partnerships are significantly current in Africa. In developed international locations, plant biotechnology can also be used for non-food functions, such because the pharmaceutical, biofuel, starch, paper and textile industries.

Trypsin Activity Assay Kit

3043 1 kit
EUR 580.26
Description: Trypsin Activity Assay Kit

Protease Activity Assay Kit

AR4011-unit unit
EUR 408

Mitochondria Activity Assay Kit

KC310100 1 kit
EUR 417

DAG Kinase Activity Assay Kit

MET-5036 50 assays
EUR 540

Caspase-1 Activity Assay Kit

AR4003-100Assays 100 Assays
EUR 616.8

Caspase-1 Activity Assay Kit

AR4003-25Assays 25 Assays
EUR 283.2

Caspase-1 Activity Assay Kit

AR4003-50Assays 50 Assays
EUR 408

Caspase-2 Activity Assay Kit

AR4004-100Assays 100 Assays
EUR 616.8

Caspase-2 Activity Assay Kit

AR4004-25Assays 25 Assays
EUR 283.2

Caspase-2 Activity Assay Kit

AR4004-50Assays 50 Assays
EUR 408

Hexokinase (HK) Activity Assay Kit

MET-5087 100 assays
EUR 609.6

Beta Secretase Activity Assay Kit

55R-1383 100 assays
EUR 1002
Description: Assay Kit for detection of Beta Secretase Activity in the research laboratory

KinaseSTAR JNK Activity Assay Kit

K2079-40 40 assays
EUR 885.6

KinaseSTAR Akt Activity Assay Kit

K2080-40 40 assays
EUR 885.6

JNK Activity Assay Kit, KinaseSTAR

K431-40 each
EUR 796.8

Akt Activity Assay Kit, KinaseSTAR

K435-40 each
EUR 816

OxiSelect ORAC Activity Assay Kit

STA-345 192 assays
EUR 692.4
Description: The ORAC assay is a powerful tool to measure the antioxidant capacity of biomolecules. Our OxiSelect ORAC Activity Assay measures this capacity in less than 2 hours from a wide variety of sample types.

OxiSelect ORAC Activity Assay Kit

STA-345-5 5 x 192 assays
EUR 2732.4
Description: The ORAC assay is a powerful tool to measure the antioxidant capacity of biomolecules. Our OxiSelect ORAC Activity Assay measures this capacity in less than 2 hours from a wide variety of sample types.

OxiSelect HORAC Activity Assay Kit

STA-346 192 assays
EUR 692.4
Description: The HORAC assay is a powerful tool to measure the antioxidant capacity of biomolecules. Our OxiSelect HORAC Activity Assay measures the degradation of free hydroxyl radicals in less than 2 hours from a wide variety of sample types.

OxiSelect HORAC Activity Assay Kit

STA-346-5 5 x 192 assays
EUR 2732.4
Description: The HORAC assay is a powerful tool to measure the antioxidant capacity of biomolecules. Our OxiSelect HORAC Activity Assay measures the degradation of free hydroxyl radicals in less than 2 hours from a wide variety of sample types.

MAT Activity Assay

IK00401 96 tests
EUR 1012.8
Description: Methionine Adenosyltransferase (MAT) activity assay kit

GST Colorimetric Activity Assay Kit

55R-1353 100 assays
EUR 847.2
Description: Assay Kit for detection of GST activity in the research laboratory

Acid Phosphatase Activity Assay Kit

55R-1405 500 assays
EUR 525.6
Description: Assay Kit for detection of Acid Phosphatase in the research laboratory

Acid Phosphatase Activity Assay Kit

55R-1866 500 assays
EUR 580.8
Description: Assay Kit for detection of Acid Phosphatase in the research laboratory

GST Colorimetric Activity Assay Kit

K263-100 each
EUR 588

GST Fluorometric Activity Assay Kit

K260-100 each
EUR 561.6

GST Fluorometric Activity Assay Kit

K2105-100 100 assays
EUR 602.4

GST Colorimetric Activity Assay Kit

K2108-100 100 assays
EUR 634.8

CETP Activity Assay

KT-782 100 tests
EUR 644

HDAC6 Activity Assay Kit (Fluorometric)

K466-100 each
EUR 757.2

Beta Hexosaminidase Activity Assay Kit

MET-5095 100 assays
EUR 609.6

Urease Activity Assay Kit (Colorimetric)

K378-100 each
EUR 601.2

ATPase Activity Assay Kit (Colorimetric)

K417-100 each
EUR 516

96-Well ROCK Activity Assay Kit

STA-416 96 assays
EUR 1027.2
Description: Rho-associated Kinase (ROCK) mediates Rho signaling and reorganizes the actin cytoskeleton by phosphorylation of several substrates that contribute to the assembly of actin filaments and contractility. ROCK inactivates myosin phosphatase through the specific phosphorylation of myosin phosphatase target subunit 1 (MYPT1) at Thr-696, which results in an increase in the phosphorylated content of the 20-kDa myosin light chain (MLC20). Our 96-Well ROCK Activity Assay Kit uses a safe, non-radioactive format to measure the level of active Rho Kinase in cell or tissue lysates. The kit contains a strip-well plate pre-coated with recombinant MYPT1.

96-Well ROCK Activity Assay Kit

STA-416-5 5 x 96 assays
EUR 4228.8
Description: Rho-associated Kinase (ROCK) mediates Rho signaling and reorganizes the actin cytoskeleton by phosphorylation of several substrates that contribute to the assembly of actin filaments and contractility. ROCK inactivates myosin phosphatase through the specific phosphorylation of myosin phosphatase target subunit 1 (MYPT1) at Thr-696, which results in an increase in the phosphorylated content of the 20-kDa myosin light chain (MLC20). Our 96-Well ROCK Activity Assay Kit uses a safe, non-radioactive format to measure the level of active Rho Kinase in cell or tissue lysates. The kit contains a strip-well plate pre-coated with recombinant MYPT1.

Alkaline Phosphatase Activity Assay Kit

55R-1402 500 assays
EUR 888
Description: Assay Kit for detection of Alkaline Phosphatase in the research laboratory

Alkaline Phosphatase Activity Assay Kit

55R-1406 500 assays
EUR 525.6
Description: Assay Kit for detection of Alkaline Phosphatase in the research laboratory

Uricase Activity Assay Kit (Fluorometric)

K734-100 each
EUR 614.4

Plasmin Activity Assay Kit (Colorimetric)

K945-100 each
EUR 535.2

Plasmin Activity Assay Kit (Fluorometric)

K381-100 each
EUR 548.4

Sirtuin Activity Assay Kit (Fluorometric)

K324-100 each
EUR 686.4

Tryptase Activity Assay

TBS2101 100 tests
EUR 280

Lysozyme Activity Assay Kit (Fluorometric)

K236-100 each
EUR 588

Sulfatase Activity Assay Kit (Colorimetric)

K675-100 each
EUR 783.6

?-Xylosidase Activity Assay Kit (Fluorometric)

K981-100 each
EUR 705.6

Neprilysin Activity Assay Kit (Fluorometric)

K487-100 each
EUR 732

Lysosomal Intracellular Activity Assay Kit

K448-50 each
EUR 652.8

Tyrosinase Activity Assay Kit (Colorimetric)

K742-100 each
EUR 698.4

PDE4B Cell-Based Activity Assay Kit

79526 500 rxns.
EUR 610
Description: Phosphodiesterases (PDEs) play an important role in the dynamic regulation of cAMP and cGMP signaling. PDE4B has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP. Inhibition of PDE4B activity by its inhibitors leads to an elevated intracellular level of cAMP. The PDE4B gene encodes at least 4 different isoforms, and has been linked to inflammation in monocytes by its regulation of the toll-receptor pathway. It is also highly expressed in the central nervous system, and has been targeted as a potential treatment for autism, depression, schizophrenia, and other conditions._x000D_The PDE4B cell-based activity assay kit is designed for screening inhibitors of PDE4B1 in cultured cells. The assay is based on transfecting cells with the CRE luciferase reporter. CRE reporter contains the firefly luciferase gene under the control of cAMP response element (CRE). Elevation of intracellular cAMP activates CRE binding protein (CREB) to bind CRE and induce the expression of luciferase. Forskolin is commonly used to raise the intracellular level of cAMP in cell physiology studies. When cells transiently transfected with CRE reporter are activated by forskolin, the intracellular level of cAMP is upregulated, which induces the expression of CRE luciferase reporter. However, when cells are co-transfected with PDE4B1 expression vector and CRE reporter, the level of forskolin-induced cAMP is reduced, resulting in lower expression level of luciferase. When cells are treated with PDE4B inhibitor to inhibit PDE4B1 activity, cAMP level is restored, resulting in higher luciferase activity._x000D_The kit includes CRE luciferase reporter (premixed with constitutively-expressing Renilla (sea pansy) luciferase vector that serves as an internal control for transfection efficiency), PDE4B1 expression vector, and forskolin.

PDE4D Cell-Based Activity Assay Kit

60505 500 rxns.
EUR 645
Description: The PDE4D cell-based activity assay is designed for screening inhibitors of PDE4D7 in cultured cells. The assay is based on transfecting cells with the CRE luciferase reporter. _x000D_CRE reporter contains the firefly luciferase gene under the control of cAMP response element (CRE). Elevation of intracellular cAMP activates CRE binding protein (CREB) to bind CRE and induce the expression of luciferase. When cells transiently transfected with CRE reporter are activated by forskolin, the intracellular level of cAMP is upregulated, which induces the expression of CRE luciferase reporter. However, when cells are co-transfected with PDE4D7 expression vector and CRE reporter, the level of forskolin-induced cAMP is reduced, resulting in lower expression level of luciferase. When cells are treated with PDE4D inhibitor to inhibit PDE4D7 activity, cAMP level is restored, resulting in higher luciferase activity.

Lipoxygenase Activity Assay Kit (Fluorometric)

K978-100 each
EUR 783.6

Chymotrypsin Activity Assay Kit (Fluorometric)

K352-100 each
EUR 588

Acetylcholinesterase Activity Assay Kit - 100 Assays

AR4001-unit unit
EUR 380.4

?-Glucuronidase Activity Assay Kit (Fluorometric)

K514-100 each
EUR 744

MAT Activity Assay 3

IK00403 48 tests
EUR 603.6
Description: Methionine Adenosyltransferase (MAT) activity assay kit

Genorise® Tryptase Activity Assay Kit

GR107043 500 tests
EUR 258

Cholinesterase Activity Assay Kit (Colorimetric)

K975-100 each
EUR 770.4

Deubiquitinase Activity Assay Kit (Fluorometric)

K485-100 each
EUR 639.6

DNAse I Activity Assay Kit (Fluorometric)

K429-100 each
EUR 836.4

Chitotriosidase Activity Assay Kit (Fluorometric)

K512-100 each
EUR 744

Transglutaminase Activity Assay Kit (Colorimetric)

K571-100 each
EUR 861.6

HAT Activity Colorimetric Assay Kit

K2033-100 100 assays
EUR 668.4

HAT Activity Fluorometric Assay Kit

K2034-100 100 assays
EUR 668.4

HAT Activity Colorimetric Assay Kit

K332-100 each
EUR 646.8

HAT Activity Fluorometric Assay Kit

K334-100 each
EUR 646.8

Factor XIa Activity Assay Kit (Colorimetric)

K973-100 each
EUR 738

Factor IXa Activity Assay Kit (Fluorometric)

K364-100 each
EUR 588

Intracellular Total ROS Activity Assay Kit

9144 100
EUR 341

Methyltransferase Activity Assay Kit (Colorimetric)

K986-100 each
EUR 777.6

Methyltransferase Activity Assay Kit (Fluorometric)

K521-100 each
EUR 679.2

DPP4 Activity Fluorometric Assay Kit

K779-100 each
EUR 652.8

HDAC Activity Fluorometric Assay Kit

K2031-100 100 assays
EUR 602.4

HDAC Activity Colorimetric Assay Kit

K2032-100 100 assays
EUR 602.4

PLTP Activity Fluorometric Assay Kit

K2087-100 100 assays
EUR 802.8

CETP Activity Fluorometric Assay Kit

K2089-100 100 assays
EUR 870

DPP4 Activity Fluorometric Assay Kit

K2178-100 100 assays
EUR 668.4

HDAC Activity Colorimetric Assay Kit

K331-100 each
EUR 588

HDAC Activity Fluorometric Assay Kit

K330-100 each
EUR 588

HDAC Activity Fluorometric Assay Kit

K2031-96 96 tests
EUR 486
Description: Detects HDAC activity, high throughput screening (HTS).

HDAC Activity Colorimetric Assay Kit

K2032-96 96 tests
EUR 486
Description: Detects HDAC activity, high throughput screening (HTS).

p53 Transcription Factor Activity Assay Kit

K923-100 each
EUR 639.6

Factor XIIa Activity Assay Kit (Colorimetric)

K994-100 each
EUR 751.2

Superoxide Dismutase (SOD) Activity Assay Kit

K2035-100 100 assays
EUR 518.4

Caspase-3 Activity Assay Kit (Luminometric)

K186-100 each Ask for price

Renin Activity Fluorometric Assay Kit

K800-100 each
EUR 627.6

HDAC3 Activity Fluorometric Assay Kit

K343-100 each
EUR 574.8

HDAC8 Activity Fluorometric Assay Kit

K348-100 each
EUR 588

TEV Protease Activity Assay Kit (Fluorometric)

K842-100 each
EUR 601.2

Mitochondrial Complex III Activity Assay Kit

K520-100 each
EUR 836.4

Factor XIIIa Activity Assay Kit (Colorimetric)

K522-100 each
EUR 744

Cathepsin E Activity Assay Kit (Fluorometric)

K165-100 each
EUR 764.4

Lactate Dehydrogenase (LDH) Activity Assay Kit

K2228-500 500 assays
EUR 634.8

Factor VIIIa Activity Assay Kit (Fluorometric)

K358-100 each
EUR 646.8

Lysyl Oxidase Activity Assay Kit (Fluorometric)

K928-100 each
EUR 639.6

Glyoxalase I Activity Assay Kit (Colorimetric)

K591-100 each
EUR 588

ADPsensor? Universal Kinase Activity Assay Kit

K212-100 each
EUR 698.4

Lipase Activity Colorimetric Assay Kit

K722-100 each
EUR 614.4

Lipase Activity Colorimetric Assay Kit

K2227-100 100 assays
EUR 619.2

?-L-Fucosidase Activity Assay Kit (Fluorometric)

K542-100 each
EUR 627.6

Trypsin Activity Colorimetric Assay Kit

K771-100 each
EUR 542.4

Amylase Activity Colorimetric Assay Kit

K711-100 each
EUR 489.6

Calpain Activity Fluorometric Assay Kit

K2062-100 100 assays
EUR 752.4

Trypsin Activity Colorimetric Assay Kit

K2176-100 100 assays
EUR 536.4

Calpain Activity Fluorometric Assay Kit

K240-100 each
EUR 705.6

Amylase Activity Colorimetric Assay Kit

K2225-100 100 assays
EUR 468

5?-Nucleotidase Activity Assay Kit (Colorimetric)

K992-100 each
EUR 796.8

Oxalate Oxidase Activity Assay Kit (Fluorometric)

K509-100 each
EUR 574.8

Diamine Oxidase Activity Assay Kit (Fluorometric)

K496-100 each
EUR 679.2

HDAC2 Immunoprecipitation (IP) & Activity Assay Kit

K341-25 each
EUR 1045.2

HDAC1 Immunoprecipitation (IP) & Activity Assay Kit

K342-25 each
EUR 1038

HDAC3 Immunoprecipitation (IP) & Activity Assay Kit

K344-25 each
EUR 901.2

?-Secretase (BACE1) Activity Assay Kit (Fluorometric)

K388-100 each
EUR 724.8

Caspase1 Activity Assay Kit(Colorimetric Method)

E-CK-A381-100Assays 100 Assays
EUR 228

Caspase1 Activity Assay Kit(Colorimetric Method)

E-CK-A381-20Assays 20 Assays
EUR 68

Caspase1 Activity Assay Kit(Colorimetric Method)

E-CK-A381-50Assays 50 Assays
EUR 136

Caspase2 Activity Assay Kit(Colorimetric Method)

E-CK-A382-100Assays 100 Assays
EUR 228

Caspase2 Activity Assay Kit(Colorimetric Method)

E-CK-A382-20Assays 20 Assays
EUR 68

Caspase2 Activity Assay Kit(Colorimetric Method)

E-CK-A382-50Assays 50 Assays
EUR 136

Caspase4 Activity Assay Kit(Colorimetric Method)

E-CK-A384-100Assays 100 Assays
EUR 228

Caspase4 Activity Assay Kit(Colorimetric Method)

E-CK-A384-20Assays 20 Assays
EUR 68

Caspase4 Activity Assay Kit(Colorimetric Method)

E-CK-A384-50Assays 50 Assays
EUR 136

Caspase6 Activity Assay Kit(Colorimetric Method)

E-CK-A386-100Assays 100 Assays
EUR 228

Caspase6 Activity Assay Kit(Colorimetric Method)

E-CK-A386-20Assays 20 Assays
EUR 68

Caspase6 Activity Assay Kit(Colorimetric Method)

E-CK-A386-50Assays 50 Assays
EUR 136

Caspase8 Activity Assay Kit(Colorimetric Method)

E-CK-A388-100Assays 100 Assays
EUR 228

Caspase8 Activity Assay Kit(Colorimetric Method)

E-CK-A388-20Assays 20 Assays
EUR 68

Caspase8 Activity Assay Kit(Colorimetric Method)

E-CK-A388-50Assays 50 Assays
EUR 136

Caspase9 Activity Assay Kit(Colorimetric Method)

E-CK-A389-100Assays 100 Assays
EUR 228

Caspase9 Activity Assay Kit(Colorimetric Method)

E-CK-A389-20Assays 20 Assays
EUR 68

Caspase9 Activity Assay Kit(Colorimetric Method)

E-CK-A389-50Assays 50 Assays
EUR 136

Protease Activity Fluorometric Assay Kit

K781-100 each
EUR 464.4

Fumarase Activity Colorimetric Assay Kit

K596-100 each
EUR 783.6

Aldolase Activity Colorimetric Assay Kit

K665-100 each
EUR 796.8

Arginase Activity Colorimetric Assay Kit

K755-100 each
EUR 646.8

Thrombin Activity Fluorometric Assay Kit

K373-100 each
EUR 836.4
For instance, crops are modified to particularly produce molecules with therapeutic makes use of, or with an improved biomass conversion effectivity, or producing bigger volumes of feedstocks for biofuels. Various plant breeding applied sciences are actually utilized in your entire spectrum of plant biotechnology: transgenesis producing proteins or RNAi. Cisgenesis (transgenes remoted from a crossable donor plant) and intragenesis (transgenes originate from the identical species or a crossable species), null segregants are additionally used. To date, the following technology precision gene enhancing instruments are developed in primary analysis. They embody: clustered recurrently interspaced brief palindromic repeats (CRISPR), oligonucleotide-directed mutagenesis (ODM), transcription activator-like results nucleases (TALENs) and zinc-finger nuclease (ZFN).

 

Additive Biotech-Chances, challenges, and recent applications of additive manufacturing technologies in biotechnology.

Additive Biotech-Chances, challenges, and recent applications of additive manufacturing technologies in biotechnology.

The variety and complexity of biotechnological applications are continually rising, with ever increasing ranges of manufacturing hosts, cultivation situations and measurement duties. Consequently, many analytical and cultivation programs for biotechnology and bioprocess engineering, similar to microfluidic units or bioreactors, are tailored to exactly fulfill the necessities of particular measurements or cultivation duties. Additive manufacturing (AM) technologies supply the likelihood of fabricating tailored 3D laboratory tools instantly from CAD designs with beforehand inaccessible ranges of freedom in phrases of structural complexity.

This assessment discusses the historic background of these technologies, their most promising present implementations and the related workflows, fabrication processes and materials specs, along with some of the key challenges related to utilizing AM in biotechnology/bioprocess engineering. To illustrate the good potential of AM, chosen examples in microfluidic units, 3D-bioprinting/biofabrication and bioprocess engineering are highlighted.

Cuban advances in biotech have made headlines, notably for the reason that US-Cuba rapprochement and signing of the historic memorandum of understanding between the US Department of Health and Human Services and Cuba’s Ministry of Public Health in June. Some 34 Cuban establishments with 22,000 workers are the spine of a biotech trade that dates to the early 1980s, acquiring novel merchandise which have sparked curiosity amongst potential international companions. While a quantity of these Cuban merchandise are registered in numerous nations, their testing in the USA stays ensnared in the pink tape of embargo legal guidelines that are inclined to make buyers skittish and thus delay, if not curtail, joint analysis and scientific trial applications to the FDA.

Safety Profile of Anticancer and Immune-Modulating Biotech Drugs Used in a Real World Setting in Campania Region (Italy): BIO-Cam Observational Study.

To examine the prevalence of hostile occasions (AEs) in naïve sufferers receiving biotech medication. Design: A potential observational examine. Setting: Onco-hematology, Hepato-gastroenterology, Rheumatology, Dermatology, and Neurology Units in Campania Region (Italy). Participants: 775 sufferers (53.81% feminine) with imply age 56.0 (SD 15.2). The imply follow-up/affected person was 3.48 (95% confidence interval 3.13-3.84). Main consequence measures: We collected all AEs related to biotech medication, together with severe infections and malignancies.

Serious AEs have been outlined in keeping with the International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use, scientific security knowledge administration: definitions and requirements for expedited reporting E2A guideline. Results: The majority of the examine inhabitants was enrolled in Onco-hematology and Rheumatology Units and the commonest analysis have been hematological malignancies, adopted by rheumatoid arthritis, colorectal most cancers, breast most cancers, and psoriatic arthritis.

The mostly prescribed biotech medication have been rituximab, bevacizumab, infliximab, trastuzumab, adalimumab, and cetuximab. Out of 775 sufferers, 320 skilled a minimum of one AE. Most of sufferers skilled AEs to cetuximab remedy, rituximab and trastuzumab. Comparing feminine and male inhabitants, our findings highlighted a statistically important distinction in phrases of AEs for adalimumab (35.90% vs. 7.41%, p < 0.001) and etanercept (27.59% vs. 10.00%, p = 0.023). Considering all biotech medication, we noticed a peak for all AEs prevalence at follow-up 91-180 days class. Bevacizumab, brentuximab, rituximab, trastuzumab and cetuximab have been extra generally related to severe hostile occasions; most of these have been probably associated to biotech medication, in keeping with causality evaluation.

Three circumstances of severe infections occurred. Conclusions: The outcomes of our examine demonstrated that almost all of AEs weren’t severe and anticipated. Few circumstances of severe infections occurred, whereas no case of malignancy did. Overall, the protection profile of biotech medication used in our inhabitants was much like these noticed in pivotal trials. Notwithstanding the optimistic outcomes of our examine, some security issues nonetheless stay unresolved. In order to gather extra effectiveness and security knowledge on biotech medication, the gathering and evaluation of actual world knowledge needs to be endorsed in addition to the administration of post-authorization research.

 Additive Biotech-Chances, challenges, and recent applications of additive manufacturing technologies in biotechnology.

What Will Be the Benefits of Biotech Wheat for European Agriculture?

In European nations, wheat occupies the biggest crop space with excessive yielding manufacturing. France, a significant producer and exporter in Europe, ranks the fifth producer worldwide. Biotic stresses are European farmers’ main challenges (fungal and viral ailments, and insect pests) adopted by abiotic ones similar to drought and grain protein composition. During the final 40 years, 1136 scientific articles on biotech wheat have been printed by USA adopted by China, Australia, Canada, and European Union with the UK. European analysis focuses on pests and ailments resistances utilizing broadly marker-assisted choice (MAS). Transgenesis is used in fundamental analysis to develop resistance towards some fungi (Fusarium head blight) whereas RNA interference (RNAi) silencing is used towards some fungi and virus.

Luciferase Reporter Gene Assay Kit

Z5030003 1,000 assays
EUR 1118

SuperLight™ Luciferase Reporter Gene Assay Kit

SLLU-01K 1000
EUR 459
Description: Bright bioluminescent reagent system for rapid quantitation of luciferase reporter gene expression in transfected cells and high-throughput drug screens. Key Features: High sensitivity and wide detection range. Detection of as little of 2 fg luciferase and as few as 4 cells. Plus, the emitted light is linear over seven orders of magnitude. Compatible with routine laboratory and HTS formats. Assays can be performed in tubes or microplates, on LJL Analyst, Berthold Luminometer, Top-Count, MicroBeta counters, chemiluminescent image plate readers (CLIPR/LeadSeeker). Assay reagents compatible with all liquid handling systems. Fast and convenient. Homogeneous "mix-and-measure" assay allows detection of luciferase levels within 10 minutes. The optimally combined reagent system allows a single addition step, and simultaneous cell lysis and detection. Robust and amenable to HTS. Z factors of 0.6 to 0.8 are observed in 96-well and 384-well plates. Can be readily automated on HTS liquid handling systems. Method: Luminescence. Samples: Cells etc. Species: All. Procedure: Assay takes 2 min. Kit size: 1000 tests. Detection limit: 2 fg luciferase.

SuperLight™ Luciferase Reporter Gene Assay Kit

SLLU-200 200
EUR 169
Description: Bright bioluminescent reagent system for rapid quantitation of luciferase reporter gene expression in transfected cells and high-throughput drug screens. Key Features: High sensitivity and wide detection range. Detection of as little of 2 fg luciferase and as few as 4 cells. Plus, the emitted light is linear over seven orders of magnitude. Compatible with routine laboratory and HTS formats. Assays can be performed in tubes or microplates, on LJL Analyst, Berthold Luminometer, Top-Count, MicroBeta counters, chemiluminescent image plate readers (CLIPR/LeadSeeker). Assay reagents compatible with all liquid handling systems. Fast and convenient. Homogeneous "mix-and-measure" assay allows detection of luciferase levels within 10 minutes. The optimally combined reagent system allows a single addition step, and simultaneous cell lysis and detection. Robust and amenable to HTS. Z factors of 0.6 to 0.8 are observed in 96-well and 384-well plates. Can be readily automated on HTS liquid handling systems. Method: Luminescence. Samples: Cells etc. Species: All. Procedure: Assay takes 2 min. Kit size: 1000 tests. Detection limit: 2 fg luciferase.

SuperLight™ Luciferase Reporter Gene Assay Kit

SLLU-500 500
EUR 299
Description: Bright bioluminescent reagent system for rapid quantitation of luciferase reporter gene expression in transfected cells and high-throughput drug screens. Key Features: High sensitivity and wide detection range. Detection of as little of 2 fg luciferase and as few as 4 cells. Plus, the emitted light is linear over seven orders of magnitude. Compatible with routine laboratory and HTS formats. Assays can be performed in tubes or microplates, on LJL Analyst, Berthold Luminometer, Top-Count, MicroBeta counters, chemiluminescent image plate readers (CLIPR/LeadSeeker). Assay reagents compatible with all liquid handling systems. Fast and convenient. Homogeneous "mix-and-measure" assay allows detection of luciferase levels within 10 minutes. The optimally combined reagent system allows a single addition step, and simultaneous cell lysis and detection. Robust and amenable to HTS. Z factors of 0.6 to 0.8 are observed in 96-well and 384-well plates. Can be readily automated on HTS liquid handling systems. Method: Luminescence. Samples: Cells etc. Species: All. Procedure: Assay takes 2 min. Kit size: 1000 tests. Detection limit: 2 fg luciferase.

SuperLight™ Dual Luciferase Reporter Gene Assay Kit

SLDL-100 100
EUR 189
Description: Bioluminescent reagent system for rapid quantitation of firelfy and Ranilla luciferase reporter gene expression in transfected cells. Key Features: High sensitivity and wide detection range. Detection of as little of 2 fg luciferase. Compatible with routine laboratory and HTS formats. Assays can be performed in tubes or microplates, and measured with any luminometer. Can be readily automated on HTS liquid handling systems. Fast and convenient. Three step assay allows detection of dual luciferase levels within 20 minutes. Method: Luminescence. Samples: Cells etc. Species: All. Procedure: Assay takes 20 min. Kit size: 100 tests. Detection limit: 2 fg luciferase.

Amplite® Luciferase Reporter Gene Assay Kit *Bright Glow*

12519 10 plates
EUR 446

Amplite® Luciferase Reporter Gene Assay Kit *Bright Glow*

12518-1plate 1 plate
EUR 166
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Luciferase Reporter Gene Assay Kit *Bright Glow*

12519-10plates 10 plates
EUR 446
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Luciferase Reporter Gene Assay Kit *Bright Glow*

12520-100plates 100 plates
EUR 3321
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Gaussia Luciferase Reporter Gene Assay Kit *Bright Glow*

12532 100 plates
EUR 4447

Amplite® Renilla Luciferase Reporter Gene Assay Kit *Bright Glow*

12536 10 plates
EUR 1070

Luciferase Reporter Assay Kit

55R-1540 200 assays
EUR 294
Description: Assay Kit for detection of Luciferase Reporter in the research laboratory

Luciferase Reporter Assay Kit

K801-200 each
EUR 235.2

Luciferase Reporter Assay Kit

K2181-200 200 assays
EUR 217.2

Amplite® Gaussia Luciferase Reporter Gene Assay Kit *Bright Glow*

12530-1plate 1 plate
EUR 222
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Gaussia Luciferase Reporter Gene Assay Kit *Bright Glow*

12531-10Plates 10 Plates
EUR 846
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Gaussia Luciferase Reporter Gene Assay Kit *Bright Glow*

12532-100plates 100 plates
EUR 4447
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Renilla Luciferase Reporter Gene Assay Kit *Bright Glow*

12535-1plate 1 plate
EUR 222
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Renilla Luciferase Reporter Gene Assay Kit *Bright Glow*

12536-10plates 10 plates
EUR 1070
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Renilla Luciferase Reporter Gene Assay Kit *Bright Glow*

12537-100plates 100 plates
EUR 4447
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Dual Luciferase Reporter Assay Kit

DL101-01 100 rxn
EUR 309.6

ARE Luciferase Reporter Lentivirus

79869 500 µl x 2
EUR 875
Description: The Nrf2 antioxidant response pathway plays an important role in the cellular antioxidant defense. Nrf2, a basic leucine zipper transcription factor, induces the expression of antioxidant and phase II enzymes by binding to the ARE (antioxidant response element) region of the gene promoter. Under basal conditions, Nrf2 is retained in the cytosol by binding to the cytoskeletal protein Keap1. Upon exposure to oxidative stress or other ARE activators, Nrf2 is released from Keap1 and translocates to the nucleus, where it can bind to the ARE, leading to the expression of antioxidant and phase II enzymes that protect the cell from oxidative damage.
The ARE Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by ARE located upstream of the minimal TATA promoter. After transduction, activation of the Nrf2 antioxidant response pathway in the target cells can be monitored by measuring the luciferase activity.

SRE Luciferase Reporter Lentivirus

78627 500 µl x 2
EUR 835
Description: The SRE (Serum Response Element) Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by the Serum Response Element located upstream of the minimal TATA promoter . After transduction, activation of the MAPK/ERK signaling pathway in the target cells can be monitored by measuring the luciferase activity.

Myc Luciferase Reporter Lentivirus

78628 500 µl x 2
EUR 835
Description: The Myc Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by the Myc response element located upstream of the minimal TATA promoter and an antibiotic selection gene (puromycin) for the selection of stable clones. After transduction, the Myc signaling pathway in the target cells can be monitored by measuring the luciferase activity.

UAS Luciferase Reporter Lentivirus

78631 500 µl x 2
EUR 835
Description: The UAS (Upstream Activation Sequence) Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by a multimerized GAL4 upstream activation sequence (UAS) located upstream of the minimal TATA promoter and an antibiotic selection gene (puromycin) for the selection of stable clones. After transduction, the UAS-controlled signaling pathway in the target cells can be monitored by measuring the luciferase activity.

p53 Luciferase Reporter Lentivirus

78666 500 µl x 2
EUR 835
Description: The p53 Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce most types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by p53 response elements located upstream of the minimal TATA promoter (Figure 1) and an antibiotic selection gene (puromycin) for the selection of stable clones. After transduction, p53-regulated gene expression in the target cells can be monitored by measuring the luciferase activity.

HRE Luciferase Reporter Lentivirus

78668 500 µl x 2
EUR 835
Description: The Hypoxia Response Element (HRE) Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce most types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by four copies of a hypoxia response elements (HRE) located upstream of the minimal TATA promoter (Figure 1) and an antibiotic selection gene (puromycin) for the selection of stable clones. After transduction, the induction of hypoxia in the target cells can be monitored by measuring the luciferase activity.

TEAD Luciferase Reporter Lentivirus

79833 500 µl x 2
EUR 875
Description: The Hippo pathway regulates cell proliferation and cell death. It is activated by high cell density and cell stress to stop cell proliferation and induce apoptosis. The mammalian Hippo pathway comprises MST kinases and LATS kinases. When the Hippo pathway is activated, MST kinases phosphorylate LATS kinases, which phosphorylate transcriptional co-activators YAP and TAZ. Unphosphorylated YAP and TAZ remain in nucleus and interact with TEAD/TEF transcriptional factors to turn on cell cycle-promoting gene transcription. However, when phosphorylated, YAP and TAZ are recruited from the nucleus to the cytosol, so that the YAP and TAZ-dependent gene transcription is turned off. Dysfunction of the Hippo pathway is frequently detected in human cancer and its down-regulation correlates with the aggressive properties of cancer cells and poor prognosis.
The TEAD Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by the TEAD response elements located upstream of the minimal TATA promoter. After transduction, activation of the Hippo pathway in the target cells can be monitored by measuring the luciferase activity._x000D_

STAT3 Luciferase Reporter Lentivirus

79744 500 µl x 2
EUR 860
Description: The STAT3 Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene under the control of STAT3-responsive element located upstream of the minimal TATA promoter. After transduction, activation of the STAT3 signaling pathway in the target cells can be monitored by measuring the luciferase activity._x000D_

STAT5 Luciferase Reporter Lentivirus

79745 500 µl x 2
EUR 835
Description: The STAT5 Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene under the control of STAT5-responsive element located upstream of the minimal TATA promoter. After transduction, activation of the STAT5 signaling pathway in the target cells can be monitored by measuring the luciferase activity.

NF-κB Luciferase Reporter Lentivirus

79564 500 µl x 2
EUR 875
Description: The NF-κB Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After transduction, activation of the NF-κB signaling pathway in the target cells can be monitored by measuring the luciferase activity.

Bald VSV Delta G (Luciferase Reporter)

78636-1 100 µl
EUR 395
Description: The bald VSV Delta G (Luciferase Reporter) was produced without envelope glycoproteins. It contains the firefly luciferase gene as the reporter. The bald VSV Delta G (Luciferase Reporter) can serve as a negative control when studying virus entry initiated by specific interactions between virus particles and receptors.

Bald VSV Delta G (Luciferase Reporter)

78636-2 500 µl x 2
EUR 1995
Description: The bald VSV Delta G (Luciferase Reporter) was produced without envelope glycoproteins. It contains the firefly luciferase gene as the reporter. The bald VSV Delta G (Luciferase Reporter) can serve as a negative control when studying virus entry initiated by specific interactions between virus particles and receptors.

CRE/CREB Luciferase Reporter Lentivirus

79580 500 µl x 2
EUR 835
Description: The main role of the cAMP response element, or CRE, is mediating the effects of Protein Kinase A (PKA) by way of transcription. Upon phosphorylation, CREB forms a functionally active dimer that binds the CRE element within the promoters of target genes and activates transcription. CRE is at the focus of many extracellular and intracellular signaling pathways, including cAMP, calcium, GPCR (G-protein coupled receptors) and neurotrophins. The cAMP/PKA signaling pathway is critical to numerous life processes in living organisms.The CRE/CREB Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by multimerized cAMP response element (CRE) located upstream of the minimal TATA promoter. After transduction, activation of the cAMP/PKA signaling pathway in the target cells can be monitored by measuring the luciferase activity.

NFAT Luciferase-RFP Reporter Lentivirus

78617-H 500 µl x 2
EUR 835
Description: The NFAT Luciferase-RFP Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase and RFP (Red Fluorescent Protein) cassette driven by the NFAT response element located upstream of the minimal TATA promoter and a hygromycin or puromycin selection gene to generate stable clones. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by measuring the luciferase activity or RFP expression. RFP fluoresces red-orange when excited; it has an excitation wavelength of 553 nm, and an emission wavelength of 574 nm.

NFAT Luciferase-RFP Reporter Lentivirus

78617-P 500 µl x 2
EUR 835
Description: The NFAT Luciferase-RFP Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase and RFP (Red Fluorescent Protein) cassette driven by the NFAT response element located upstream of the minimal TATA promoter and a hygromycin or puromycin selection gene to generate stable clones. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by measuring the luciferase activity or RFP expression. RFP fluoresces red-orange when excited; it has an excitation wavelength of 553 nm, and an emission wavelength of 574 nm.

STAT3 Luciferase Reporter THP-1 Cell Line

78498 2 vials
EUR 1900
Description: The STAT3 Luciferase Reporter THP-1 cell line is designed for monitoring the STAT3 signal transduction pathway. It contains a firefly luciferase gene driven by STAT3 response elements located upstream of the minimal TATA promoter. After activation by cytokines or growth factors, endogenous STAT3 binds to the DNA response elements, inducing transcription of the luciferase reporter gene.

IL-2 Luciferase Reporter Jurkat cell line

60481 2 vials
EUR 6875
Description: Human IL-2 reporter construct is stably integrated into the genome of Jurkat T-cells. The firefly luciferase gene is controlled by a human IL-2 promoter.

Human p53 Luciferase Reporter Cell Line- RKO

ABC-RC0038 1 vial Ask for price
Description: Human p53 Luciferase Reporter Cell Line- RKO is derived from human colon cancer, and stably express firefly luciferase reporter gene under the control of the p53 response element. This cell line is an ideal cellular model for monitoring the activation of p53 Pathway triggered by stimuli treatment,enforced gene expression and gene knockdown.

Human p53 Luciferase Reporter Cell Line- HeLa

ABC-RC0037 1 vial Ask for price
Description: Human p53 Luciferase Reporter Cell Line- HeLa is derived from human cervical cancer, and stably express firefly luciferase reporter gene under the control of the p53 response element. This cell line is an ideal cellular model for monitoring the activation of p53 Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Bald Lentiviral Pseudovirion (Luciferase Reporter)

79943 500 µl x 2
EUR 875
Description: The bald lentiviral pseudovirion was produced without envelope glycoproteins such as VSV-G or SARS-CoV-2 spike. It contains the firefly luciferase gene driven by a CMV promoter as the reporter. The bald lentiviral pseudovirion can serve as a negative control when studying virus entry initiated by specific interactions between virus particles and receptors._x000D_

IL-2 Promoter Luciferase Reporter Lentivirus

79825 500 µl x 2
EUR 795
Description: The IL-2 Promoter Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by the human IL-2 promoter. After transduction, activation of the IL-2 signaling pathway in the target cells can be monitored by measuring the luciferase activity._x000D_

IL-8 Promoter Luciferase Reporter Lentivirus

79827 500 µl x 2
EUR 795
Description: The IL-8 Promoter Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by the human IL-8 promoter. After transduction, activation of the IL-8 signaling pathway in the target cells can be monitored by measuring the luciferase activity._x000D_

GIPR/CRE Luciferase Reporter HEK293 Cell Line

78589 2 vials
EUR 10105
Description: Recombinant HEK293 cells expressing the firefly luciferase gene under the control of cAMP response element (CRE), and with forced expression of human GIPR (Gastric Inhibitory Polypeptide receptor; NM_000164.4). Activation of GIPR in these cells can be monitored by measuring luciferase activity._x000D_The functionality of the GIPR/CRE Luciferase Reporter HEK293 Cell Line was validated in a dose-response assay using agonists gastric inhibitory peptide (GIP) and tirzepatide hydrochloride. These agonists induce luciferase activity in a dose-dependent manner as depicted in Figure 1._x000D_

_x000D_Figure 1. Illustration of the GIPR/CRE Luciferase Reporter HEK293 Cell line.

Human GR Luciferase Reporter Cell Line-HeLa

ABC-RC0014 1 vial Ask for price
Description: Human GR Luciferase Reporter Cell Line-HeLa is derived from human cervical cancer, and stably express firefly luciferase reporter gene under the control of GR response element. This cell line is an ideal cellular model for monitoring the activation of Glucocorticoid Signaling Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human IRF Luciferase Reporter Cell Line- HepG2

ABC-RC0021 1 vial Ask for price
Description: Human IRF Luciferase Reporter Cell Line- HepG2 is derived from Human Liver Cancer, and stably express firefly luciferase reporter gene under the control of IRF response element. This cell line is an ideal cellular model for monitoring the activation of Immune Response Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human NFAT Luciferase Reporter Cell Line- HeLa

ABC-RC0023 1 vial Ask for price
Description: Human NFAT Luciferase Reporter Cell Line- HeLa is derived from human cervical cancer, and stably express firefly luciferase reporter gene under the control of NFAT response element. This cell line is an ideal cellular model for monitoring the activation of Calcium Signaling Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

NFAT Luciferase Reporter Lentivirus-79579-G

79579-G 500 µl x 2
EUR 835
Description: The NFAT Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by the NFAT response element located upstream of the minimal TATA promoter (Figure 1) and an antibiotic selection gene (hygromycin, puromycin, or G418) for the selection of stable clones. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by measuring the luciferase activity.

NFAT Luciferase Reporter Lentivirus-79579-H

79579-H 500 µl x 2
EUR 860
Description: The NFAT Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by the NFAT response element located upstream of the minimal TATA promoter and an antibiotic selection gene (hygromycin or puromycin) for the selection of stable clones. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by measuring the luciferase activity.

NFAT Luciferase Reporter Lentivirus-79579-P

79579-P 500 µl x 2
EUR 860
Description: The NFAT Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by the NFAT response element located upstream of the minimal TATA promoter and an antibiotic selection gene (hygromycin or puromycin) for the selection of stable clones. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by measuring the luciferase activity.

CGRPR/CRE Luciferase Reporter HEK293 Cell Line

78325 2 vials
EUR 10340
Description: Recombinant HEK293 cell line stably expressing full-length human Calcitonin receptor-like receptor (CALCRL/CRLR/CLR; accession number: NM_005795) and containing a firefly luciferase gene under the control of multimerized cAMP response element (CRE). This cell line can be used to measure the EC50 and IC50 of CALCRL agonists and antagonists using the luciferase reporter activity.

GR-GAL4 Luciferase Reporter Jurkat Cell Line

78525 2 vials
EUR 2275
Description: The Glucocorticoid Receptor (GR)-GAL4 Luciferase Reporter Jurkat Cell Line contains an engineered transcription factor stably integrated into the genome of Jurkat cells, which consists of the glucocorticoid receptor ligand binding domain fused to the DNA binding domain of GAL4. This fusion construct activates firefly luciferase expression which is under the control of a multimerized GAL4 upstream activation sequence (UAS). This allows for specific detection of glucocorticoid-induced activation of the glucocorticoid receptor without the need for individual transcriptional targets and with low cross-reactivity for other nuclear receptor pathways. This cell line is validated for response to stimulation of dexamethasone and to the treatment with mifepristone, an inhibitor of the glucocorticoid signaling pathway.

Human HIF Luciferase Reporter Cell Line-Hela

ABC-RC0016 1 vial Ask for price
Description: Human HIF Luciferase Reporter Cell Line-Hela is derived from human cervical cancer, and stably express firefly luciferase reporter gene under the control of HIF response element. This cell line is an ideal cellular model for monitoring the activation of Hypoxia Response Signaling Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human IRF Luciferase Reporter Cell Line- HEK293

ABC-RC0020 1 vial Ask for price
Description: Human IRF Luciferase Reporter Cell Line- HEK293 is derived from human embryonic kidney, and stably express firefly luciferase reporter gene under the control of IRF response element. This cell line is an ideal cellular model for monitoring the activation of Immune Response Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human Stat1 Luciferase Reporter Cell Line- Hela

ABC-RC0040 1 vial Ask for price
Description: Human Stat1 Luciferase Reporter Cell Line- Hela is derived from human cervical cancer,and stably express firefly luciferase reporter gene under the control of the STAT1 response element. This cell line is an ideal cellular model for monitoring the activation of JAK-STAT Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human Stat3 Luciferase Reporter Cell Line- Hela

ABC-RC0041 1 vial Ask for price
Description: Human Stat3 Luciferase Reporter Cell Line- Hela is derived from human cervical cancer, and stably express firefly luciferase reporter gene under the control of the STAT3 response element. This cell line is an ideal cellular model for monitoring the activation of JAK-STAT Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Mouse NFkB Luciferase Reporter Cell Line-MEF

ABC-RC0067 1 vial Ask for price
Description: Mouse NFkB Luciferase Reporter Cell Line-MEF is derived from murine embryonic fibroblast,and stably express firefly luciferase reporter gene under the control of NFkB response element. This cell line is an ideal cellular model for monitoring the activation of NFkB Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

NFAT Reporter (Luciferase) - THP-1 Cell Line

78320 2 vials
EUR 1810
Description: The NFAT reporter (Luciferase)-THP-1 cell line is designed for monitoring the NFAT (nuclear factor of activated T-cells) signaling pathway in THP-1 cells by measuring luciferase activity. It contains a firefly luciferase gene driven by the NFAT response element located upstream of the minimal TATA promoter. Upon activation by NFAT activators such as Ionomycin, endogenous NFAT transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene.

XRE Luciferase Reporter Lentivirus (AhR Signaling)

78672 500 µl x 2
EUR 835
Description: The Xenobiotic response element (XRE) Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce most types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by three copies of an XRE located upstream of the minimal TATA promoter (Figure 1), and an antibiotic selection gene (puromycin) for the selection of stable clones. After transduction, the activation of aryl hydrocarbon receptor (AhR) in the target cells can be monitored by measuring the luciferase activity.

Single-Luciferase Reporter Assay Kit

20-abx098133
  • EUR 679.20
  • EUR 566.40
  • 200 rxns
  • 50 rxns

Double-Luciferase Reporter Assay Kit

20-abx098134
  • EUR 904.80
  • EUR 622.80
  • 200 rxns
  • 50 rxns

ADAR1 Dual Luciferase Reporter HEK293 Cell Line

78547 2 vials
EUR 19950
Description: The ADAR1 Luciferase Reporter HEK293 cell line is designed to monitor RNA editing by Adenosine deaminase acting on RNA (ADAR1). This cell line stably expresses ADAR1 under the control of a CMV promoter and a separate ADAR editing reporter construct expressed under the control of another CMV promoter. The reporter contains the gene encoding firefly luciferase, which is constitutively expressed in the cells, upstream of the gene encoding the GluA2 ADAR substrate followed by the Renilla luciferase gene. The sequence corresponding to GluA2 has been modified to contain an amber stop codon (UAG). When edited by ADAR, this stop codon (UAG) will be changed to UIG (A to I edit), which is read as tryptophan (UGG) by the translation machinery. This edit allows translation to occur all the way to the end of the reporter mRNA and results in the expression of Renilla luciferase. Conversely, in the absence of ADAR1 activity, translation terminates at the stop codon and Renilla is not expressed. Reporter activity is read out as the Renilla Luciferase/Firefly luciferase ratio whereby inhibition of ADAR activity, and thus the UAG (stop) to UGG (tryptophan) conversion rate, will result in a dose-dependent decrease in the Renilla luciferase/Firefly luciferase ratio.

Human FXR Luciferase Reporter Cell Line-HepG2

ABC-RC0013 1 vial Ask for price
Description: Farnesoid X receptor (FXR, NR1H4) is a member of the nuclear hormone receptor superfamily. These nuclear hormone receptors are ligand-activated transcription factors that elicit their actions by binding to hormone response elements (HREs) in the promoters of target genes and regulating transcription in response to lipophilic ligands.Gentaur now offers Human FXR Luciferase Reporter Cell Line-HepG2 to the research community. This high-quality stable cell lines will facilitate further molecular studies of FXR pathway its functions.

Human NFkB Luciferase Reporter Cell Line-MCF7

ABC-RC0031 1 vial Ask for price
Description: Human NFkB Luciferase Reporter Cell Line-MCF7 is derived from human breast cancer, and stably express firefly luciferase reporter gene under the control of the NFkB response element. This cell line is an ideal cellular model for monitoring the activation of NFkB Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human NFκB Luciferase Reporter Cell Line-HeLa

ABC-RC0033 1 vial Ask for price
Description: NFκB Luciferase Reporter Cell Line-HeLa is derived from human cervical cancer, and stably express firefly luciferase reporter gene under the control of the NFkB response element. This cell line is an ideal cellular model for monitoring the activation of NFkB Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human NFkB Luciferase Reporter Cell Line-A549

ABC-KH16937 1 vial vial Ask for price
Description: Human NFkB Luciferase Reporter Cell line is derived from human lung cancer,and stably express firefly luciferase reporter gene under the control of the NFkB response element. This cell line is an ideal cellular model for monitoring the activation of NFkB Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

TMIGD2/NFAT Luciferase Reporter Jurkat Cell Line

78323 2 vials
EUR 10340
Description: Recombinant Jurkat cell line expressing firefly luciferase under the control of an NFAT response element, and with constitutive expression of human TMIGD2 (Transmembrane and immunoglobulin domain containing 2; CD28H; NM_144615). Expression of the firefly luciferase gene is driven by NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway in these cells can be monitored by measuring luciferase activity. 

IL-15 Responsive Luciferase Reporter Cell Line

78402 2 vials
EUR 10175
Description: This recombinant Jurkat cell line is a biologically relevant system to measure activation of the IL-15 cytokine receptor by IL-15. The cells were engineered for constitutive expression of human CD122 (IL-15Rβ; IL-2Rβ; NM_000878.4), and conditional expression of firefly luciferase driven by STAT5 response elements located upstream of the minimal TATA promoter. Expression of CD122 allows formation of a functional IL-15 receptor at the surface of Jurkat cells, which naturally express high levels of CD132 (also known as IL-15 receptor subunit γc). Activation of the STAT5 signaling pathway in response to IL-15 or IL-15 analogs can be monitored by measuring luciferase activity.

Human MRF Luciferase Reporter Cell Line-HEK293

ABC-RC0022 1 vial Ask for price
Description: Human MRF Luciferase Reporter Cell Line-HEK293 is derived from human embryonic Kidney, and stably express firefly luciferase reporter gene under the control of MRF response element. This cell line is an ideal cellular model for monitoring the activation of Metal response Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human NFkB Luciferase Reporter Cell Line-HepG2

ABC-RC0029 1 vial Ask for price
Description: Human NFkB Luciferase Reporter Cell Line-HepG2 is derived from human liver cancer, and stably express firefly luciferase reporter gene under the control of the NFkB response element. This cell line is an ideal cellular model for monitoring the activation of NFkB Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Mouse HIF Luciferase Reporter Cell Line-NIH3T3

ABC-RC0065 1 vial Ask for price
Description: Mouse HIF Luciferase Reporter Cell Line-NIH3T3 is derived from mouse fibroblast, and stably express firefly luciferase reporter gene under the control of the HIF response element. This cell line is an ideal cellular model for monitoring the activation of Hypoxia Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human SBE Luciferase Reporter Cell Line-HEK293

ABC-RC0121 1 vial Ask for price
Description: The SBE Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the smad binding element (SBE). SMADs are intracellular signaling mediators that transduce extracellular signals from transforming growth factor beta (TGF-beta) ligands to the nucleus where they activate downstream gene transcription. The TGF-beta signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo including cell growth, cell differentiation, apoptosis, cellular homeostasis and other cellular functions.

CD16-NFAT Luciferase Reporter Jurkat Cell Line

T6504 1x10^6 cells / 1.0 ml Ask for price

Human NFAT Luciferase Reporter Cell Line- NIH 3T3

ABC-RC0025 1 vial Ask for price
Description: Human NFAT Luciferase Reporter Cell Line- NIH 3T3 is derived from mouse fibroblast, and stably express firefly luciferase reporter gene under the control of NFAT response element. This cell line is an ideal cellular model for monitoring the activation of Calcium Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human TCF/LEF Luciferase Reporter Cell Line- HeLa

ABC-RC0043 1 vial Ask for price
Description: Human TCF/LEF Luciferase Reporter Cell Line- HeLa is derived from human cervical cancer, and stably express firefly luciferase reporter gene under the control of TCF/LEF response element. This cell line is an ideal cellular model for monitoring the activation of Wnt/b-catenin Signaling Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Mouse NFkB Luciferase Reporter Cell Line- NIH 3T3

ABC-RC0066 1 vial Ask for price
Description: Mouse NFkB Luciferase Reporter Cell Line- NIH 3T3 is derived from mouse fibroblast,and stably express firefly luciferase reporter gene under the control of the NFkB Response element. This cell line is an ideal cellular model for monitoring the activation of NFkB Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human CREB Luciferase Reporter Cell Line-HEK293

ABC-RC0008 1 vial Ask for price
Description: Human CREB Luciferase Reporter Cell Line-HEK293 is derived from human embryonic kidney, and stably express firefly luciferase reporter gene under the control of CREB response element. This cell line is an ideal cellular model for monitoring the activation of cAMP,PKA,CaMK Signaling Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human CREB Luciferase Reporter Cell Line-NIH3T3

ABC-RC0009 1 vial Ask for price
Description: Human CREB Luciferase Reporter Cell Line-NIH3T3 is derived from mouse fibroblast,and stably express firefly luciferase reporter gene under the control of CREB response element. This cell line is an ideal cellular model for monitoring the activation of cAMP, PKA, CaMK Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human HIF Luciferase Reporter Cell Line-Neuro2a

ABC-RC0017 1 vial Ask for price
Description: Human HIF Luciferase Reporter Cell Line-Neuro2a is derived from mouse neuroblastoma, and stably express firefly luciferase reporter gene under the control of HIF response element. This cell line is an ideal cellular model for monitoring the activation of Hypoxia receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human NFkB Luciferase Reporter Cell Line-HEK293

ABC-RC0028 1 vial Ask for price
Description: Human NFkB Luciferase Reporter Cell Line-HEK293 is derived from human embryonic kidney, and stably express firefly luciferase reporter gene under the control of the NFkB response element. This cell line is an ideal cellular model for monitoring the activation of NFkB Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.The Human NFKB reporter (luc) cell line-HEK293 from Gentaur is designed for screening inhibitors of NF-κB and for monitoring NF-κB signaling pathway activity. It contains a firefly luciferase gene driven by four copies of NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. The cell line has been screened using the PCR-based VenorGeM Mycoplasma Detection kit (Sigma Aldrich) to confirm the absence of Mycoplasma species.

Human AP-1 Luciferase Reporter Cell Line-HeLa

ABC-RC0004 1 vial Ask for price
Description: Human AP-1 Luciferase Reporter Cell Line-HeLa is derived from human cervical cancer, and stably express firefly luciferase reporter gene under the control of AP-1 response element. This cell line is an ideal cellular model for monitoring the activation of JNK, ERK, MAPK Signaling Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human STAT6 Luciferase Reporter Cell Line-Ba/F3

ABC-RC029L 1 vial Ask for price
Description: The human STAT6 Luciferase Reporter cell line is a stably transfected Ba/F3 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the STAT6 responsive promoter, so that the cell line is designed to measure the transcriptional activity of STAT6. Signal Transducer and Activator of Transcription 6 (STAT6) is a member of the STAT transcription factor family and plays an important role in adaptive immunity by transducing signals from extracellular cytokines including IL-4.

AZ-GR Stable HeLa Luciferase Reporter Cell Line

T3103 1x10^6 cells / 1.0 ml
EUR 3950

Mouse NFkB Luciferase Reporter Cell Line-Neuro2a

ABC-RC0068 1 vial Ask for price
Description: Mouse NFkB Luciferase Reporter Cell Line-Neuro2a is derived from mouse neuroblastoma, and stably express firefly luciferase reporter gene under the control of NFkB response element. This cell line is an ideal cellular model for monitoring the activation of NFkB receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human NFAT Luciferase Reporter Cell Line- Jurkat T

ABC-RC0024 1 vial Ask for price
Description: Human NFAT Luciferase Reporter Cell Line- Jurkat T is derived from human T lymphocyte,and stably express firefly luciferase reporter gene under the control of NFAT response element. This cell line is an ideal cellular model for monitoring the activation of Calcium Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human TCF/LEF Luciferase Reporter Cell Line- HEK293

ABC-RC0042 1 vial Ask for price
Description: Human TCF/LEF Luciferase Reporter Cell Line- HEK293 is derived from human embryonic kidney, and stably express firefly luciferase reporter gene under the control of the TCF/LEF response element. This cell line is an ideal cellular model for monitoring the activation of Wnt/b-catenin Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Monkey HIF Luciferase Reporter Cell Line-Cos-7

ABC-RC0064 1 vial Ask for price
Description: Monkey HIF Luciferase Reporter Cell Line-Cos-7 was established by transfection using a pTA-HIF-luciferase reporter vector, which contains 4 repeats of HIF binding sites, a minimal promoter upstream of the firefly luciferase coding region, along with hygromycin expression vector followed by hygromycin selection. The hygromycin resistant clones were subsequently screened for CoCl2-induced luciferase activity.

PZ-TR Stable HepG2 Luciferase Reporter Cell Line

T3177 1x10^6 cells / 1.0 ml
EUR 3950

SBE Luciferase Reporter Lentivirus (TGFβ/SMAD Pathway)

79806 500 µl x 2
EUR 875
Description: The SBE Luciferase Reporter Lentivirus (TGFβ/SMAD signaling pathway) are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by multimerized SBE-responsive element located upstream of the minimal TATA promoter. After transduction, activation of the TGFβ/SMAD signaling pathway can be monitored by measuring the luciferase activity._x000D_

KIR3DL3/IL-2 Luciferase Reporter Jurkat Cell Line

78322 2 vials
EUR 10855
Description: Recombinant Jurkat cell line expressing firefly luciferase under the control of an IL-2-responsive promoter, and with constitutive expression of human KIR3DL3 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains and Long Cytoplasmic Tail 3; GenBank accession #BC143802.1 corresponding to KIR3DL3*00402 allele). HHLA2 (B7-H7) mediates an immune-stimulatory signal via TMIGD2 (Transmembrane and immunoglobulin domain containing 2; CD28H) in naïve T cells while it delivers an immune-inhibitory signal through KIR3DL3 in activated T cells and Natural Killer (NK) cells.

Hamster ATF6 Luciferase Reporter Cell Line- CHO-K1

ABC-RC0002 1 vial Ask for price
Description: Hamster ATF6 Luciferase Reporter Cell Line- CHO-K1 is derived from Chinese Hamster Ovary, and stably express firefly luciferase reporter gene under the control of ATF6 response element. This cell line is an ideal cellular model for monitoring the activation of Unfolded Protein Response, ER stress Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human NRF2/ARE Luciferase Reporter Cell Line-MCF7

ABC-RC0036 1 vial Ask for price
Description: Human NRF2/ARE Luciferase Reporter Cell Line-MCF7 is derived from human breast cancer, and stably express firefly luciferase reporter gene under the control of the NRF2/ARE response element. This cell line is an ideal cellular model for monitoring the activation of Antioxidant Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

AZ-AHR Stable HepG2 Luciferase Reporter Cell Line

T3102 1x10^6 cells / 1.0 ml
EUR 3950

AIZ-AR Stable 22Rv1 Luciferase Reporter Cell Line

T3104 1x10^6 cells / 1.0 ml
EUR 3950

NFAT Luciferase-eGFP Reporter Jurkat Cell Line

78662 2 vials
EUR 2195
Description: Recombinant Jurkat T cells expressing both firefly luciferase and enhanced GFP (eGFP) under the control of NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway can be monitored by examining either firefly luciferase or eGFP expression.

VSV-G Pseudotyped VSV Delta G (Luciferase Reporter)

78634-1 100 µl
EUR 795
Description: The VSV-G Pseudotyped VSV Delta G (Luciferase Reporter) was produced by re-expression of VSV-G as the envelope glycoprotein using the VSV Delta G system in which VSV-G is deleted. The pseudovirions contain the firefly luciferase gene; therefore, the VSV-G mediated cell entry can be measured via luciferase activity. The VSV-G Pseudotyped VSV Delta G (Luciferase Reporter) can be used as a positive control of transduction for other VSV pseudotypes containing the envelope glycoproteins of heterologous viruses in a Biosafety Level 2 facility.

VSV-G Pseudotyped VSV Delta G (Luciferase Reporter)

78634-2 500 µl x 2
EUR 3995
Description: The VSV-G Pseudotyped VSV Delta G (Luciferase Reporter) was produced by re-expression of VSV-G as the envelope glycoprotein using the VSV Delta G system in which VSV-G is deleted. The pseudovirions contain the firefly luciferase gene; therefore, the VSV-G mediated cell entry can be measured via luciferase activity. The VSV-G Pseudotyped VSV Delta G (Luciferase Reporter) can be used as a positive control of transduction for other VSV pseudotypes containing the envelope glycoproteins of heterologous viruses in a Biosafety Level 2 facility.

Human ELK-TAD Luciferase Reporter Cell Line-HeLa

ABC-RC0011 1 vial Ask for price
Description: Human ELK-TAD Luciferase Reporter Cell Line-HeLa is derived human cervical cancer, and stably express firefly luciferase reporter gene under the control of ELK response element. This cell line is an ideal cellular model for monitoring the activation of MAPK response Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human NF-kB Luciferase Reporter Cell Line-Jurkat

ABC-RC0030 1 vial Ask for price
Description: Human NFkB Luciferase Reporter Cell Line-Jurkat is is derived from human T lymphocyte cells, and stably express firefly luciferase reporter gene under the control of the NF-kB response enhancer element. This cell line is an ideal cellular model for monitoring the activation of NFkB pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human NRF2/ARE Luciferase Reporter Cell Line-HepG2

ABC-RC0035 1 vial Ask for price
Description: Human NRF2/ARE Luciferase Reporter Cell Line-HepG2 is derived from Human Liver cancer, and stably express firefly luciferase reporter gene under the control of NRF2/ARE response element.This cell line is an ideal cellular model for monitoring the activation of Antioxidant response Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Hippo Pathway TEAD Luciferase Reporter MCF7 cell line

60618 2 vials
EUR 2445
Description: The TEAD Reporter - MCF7 cell line contains the firefly luciferase gene under the control of TEAD responsive elements stably integrated into the human breast cancer cell line, MCF7. Inside the cells, basal unphosphorylated YAP/TAZ remains in the nucleus and induces the constitutive expression of luciferase reporter. The cell line is validated for the inhibition of the expression of luciferase reporter by the activators of the Hippo pathway.

Human NRF2/ARE Luciferase Reporter Cell Line-HEK293

ABC-RC0034 1 vial Ask for price
Description: Human NRF2/ARE Luciferase Reporter Cell Line-HEK293 is derived from Human embyronic kidney,and stably express firefly luciferase reporter gene under the control of NRF2/ARE response element.This cell line is an ideal cellular model for monitoring the activation of Antioxidant response Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human INF-a/ISRE Luciferase Reporter Cell Line- HeLa

ABC-RC0019 1 vial Ask for price
Description: Human INF-a/ISRE Luciferase Reporter Cell Line- HeLa is derived human cervical cancer, and stably express firefly luciferase reporter gene under the control of IFN-α/ISRE response element. This cell line is an ideal cellular model for monitoring the activation of TYK2 and JAK1 response Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

B2M Knockout NFAT Luciferase Reporter Jurkat Cell Line

78363 2 vials
EUR 11095
Description: B2M (Beta-2-Microglobulin) has been genetically removed by CRISPR/Cas9 genome editing from NFAT Luciferase Reporter Jurkat cells. Expression of the firefly luciferase gene is driven by NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway in these cells can be monitored by measuring luciferase activity.

Human CHOP Luciferase Reporter Cell Line-Mia-Paca2

ABC-RC0007 1 vial Ask for price
Description: Human CHOP Luciferase Reporter Cell Line-Mia-Paca2 is derived from human pancreatic cancer, and stably express firefly luciferase reporter gene under the control of the Unfolded Protein Response, ER stress response element. This cell line is an ideal cellular model for monitoring the activation of Unfolded Protein Response, ER stress Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human ELK-TAD Luciferase Reporter Cell Line-HEK293

ABC-RC0010 1 vial Ask for price
Description: Human ELK-TAD Luciferase Reporter Cell Line-HEK293 is derived human embryonic kidney, and stably express firefly luciferase reporter gene under the control of ELK response element. This cell line is an ideal cellular model for monitoring the activation of MAPK response Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Hamster TCF/LEF Luciferase Reporter Cell Line- CHO-K1

ABC-RC0003 1 vial Ask for price
Description: Hamster TCF/LEF Luciferase Reporter Cell Line- CHO-K1 is derived from Chinese Hamster Ovary, and stably express firefly luciferase reporter gene under the control of TCF/LEF response element. This cell line is an ideal cellular model for monitoring the activation of Wnt /b-catenin Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Mouse NRF2/ARE Luciferase Reporter Cell Line-NIH 3T3

ABC-RC0070 1 vial Ask for price
Description: Mouse NRF2/ARE Luciferase Reporter Cell Line-NIH 3T3 is derived from Mouse fibroblast, and stably express firefly luciferase reporter gene under the control of the NRF2/ARE response element. This cell line is an ideal cellular model for monitoring the activation of Antioxidant Response Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

AP1 Luciferase Reporter Lentivirus (JNK Signaling Pathway)

79823 500 µl x 2
EUR 795
Description: The stress-activated protein kinase/c-jun N-terminal kinase (SAPK/JNK) family of proteins includes mitogen-activated protein kinases (MAPKs) that are activated by stress, inflammatory cytokines, mitogens, oncogenes, and inducers of cell differentiation and morphogenesis. Upon activation of the SAPK/JNK pathway, MAP Kinase Kinases phosphorylate and activate JNKs. The activated JNKs translocate to the nucleus where they phosphorylate and activate transcription factors such as c-Jun. c-Jun then binds to the activator protein-1 (AP1) response element and induces AP1 transcription.
The AP1 Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by AP1 response element located upstream of the minimal TATA promoter. After transduction, activation of the JNK signaling pathway and AP1 mediated activity in the target cells can be monitored by measuring the luciferase activity.

Human AR Luciferase Reporter Cell Line-MDA-MB-453

ABC-RC0005 1 vial Ask for price
Description: Human AR Luciferase Reporter Cell Line-MDA-MB-453 is derived from human breast cancer,and stably express firefly luciferase reporter gene under the control of the AR response element. This cell line is an ideal cellular model for monitoring the activation of Androgen Receptor Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human GR Luciferase Reporter Cell Line-MDA-MB-453

ABC-RC0015 1 vial Ask for price
Description: Human GR Luciferase Reporter Cell Line-MDA-MB-453 is derived from human breast cancer, and stably express firefly luciferase reporter gene under the control of the GR response element. This cell line is an ideal cellular model for monitoring the activation of Glucocorticoid Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Human NFkB Luciferase Reporter Cell Line- MDA-MB-231

ABC-RC0026 1 vial Ask for price
Description: Human NFkB Luciferase Reporter Cell Line- MDA-MB-231 is derived from Human breast cancer, and stably express firefly luciferase reporter gene under the control of NFkB response element. This cell line is an ideal cellular model for monitoring the activation of NFkB response Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Minicircle Single Reporter: EF1 Luciferase DNA (30 µg)

BLIV511MC-1 30 ug
EUR 652

Human SMAD/TGFbeta Luciferase Reporter Cell Line-HepG2

ABC-RC0039 1 vial Ask for price
Description: Human SMAD/TGFbeta Luciferase Reporter Cell Line-HepG2 is derived from human liver cancer, and stably express firefly luciferase reporter gene under the control of the SMAD 2/3 response element. This cell line is an ideal cellular model for monitoring the activation of TGFbeta pathway Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

Luciferase HeLa Reporter Cell Line-Negative Control

ABC-RC0062 1 vial Ask for price
Description: Luciferase HeLa Reporter Cell Line-Negative Control has been stably transfected with pTA-luciferase reporter vector, which contains no binding sites, a minimal promoter upstream of the firefly luciferase coding region.

Anti-BCMA CAR Jurkat/NFAT (Luciferase) Reporter Cell Line

79694 2 vials
EUR 9400
Description: The anti-BCMA CAR Jurkat/NFAT-luciferase reporter cell line is a stable cell line made from the anti-BCMA scFV CAR lentivirus (BPS Bioscience #79701). It has been validated for anti BCMA-CAR expression by FACS, and for functional activation stimulated by both soluble BCMA protein (BPS Bioscience #79467) and BCMA/CHO target cells (BPS Bioscience #79500).

Single-Luciferase (Renilla) Reporter Assay Kit

20-abx298011
  • EUR 548.40
  • EUR 322.80
  • 200 rxns
  • 50 rxns

NFAT Luciferase-eGFP Reporter Lentivirus-78656-G

78656-G 500 µl x 2
EUR 835
Description: The NFAT Luciferase-eGFP Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase and eGFP cassette driven by the NFAT response element located upstream of the minimal TATA promoter (Figure 1) and a puromycin selection gene to generate stable clones. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by measuring the luciferase activity or eGFP expression.

NFAT Luciferase-eGFP Reporter Lentivirus-78656-P

78656-P 500 µl x 2
EUR 835
Description: The NFAT Luciferase-eGFP Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase and eGFP cassette driven by the NFAT response element located upstream of the minimal TATA promoter (Figure 1) and a puromycin selection gene to generate stable clones. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by measuring the luciferase activity or eGFP expression.

Luciferase HepG2 Reporter Cell Line-Negative Control

ABC-RC0063 1 vial Ask for price
Description: Luciferase HepG2 Reporter Cell Line-Negative Control has been stably transfected with pTA-luciferase reporter vector, which contains no binding sites, a minimal promoter upstream of the firefly luciferase coding region.

TCR/B2M Knockout NFAT Luciferase Reporter Jurkat Cell Line

78557 2 vials
EUR 16695
Description: This cell line is a double knockout of TCR (T Cell Receptor) and B2M (Beta-2-Microglobulin). First, the TRAC (T-Cell Receptor Alpha Constant) and the TRBC1 (T-Cell Receptor Beta Constant 1) domains of the TCRα/β chains were genetically removed by CRISPR/Cas9 genome editing from NFAT Luciferase Reporter Jurkat cells to generate the TCR Knockout NFAT Luciferase Reporter Jurkat cell Line (BPS Bioscience #78556). These TCR knockout cells were used to generate a new cell line in which B2M was also genetically removed by CRISPR/Cas9 genome editing. _x000D_Expression of the firefly luciferase gene is driven by NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway in these cells can be monitored by measuring luciferase activity. 

Mouse SMAD/TGFbeta Luciferase Reporter Cell Line-NIH 3T3

ABC-RC0071 1 vial Ask for price
Description: Mouse SMAD/TGFbeta Luciferase Reporter Cell Line-NIH 3T3 is derived from mouse fibroblast,and stably express firefly luciferase reporter gene under the control of SMAD 2/3 response element. This cell line is an ideal cellular model for monitoring the activation of TGFbeta Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

CD160/NFAT - Luciferase Reporter - Jurkat Recombinant Cell Line

79594 2 vials
EUR 9400
Description: Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human CD160. CD160 is a GPIanchored glycoprotein member of the Ig superfamily, also known as BY55, NK1, and NK28. GenBank Accession # NM_007053._x000D__x000D_

Human Estrogen Receptor Luciferase Reporter Cell Line-T47D

ABC-RC0012 1 vial Ask for price
Description: Human Estrogen Receptor Luciferase Reporter Cell Line-T47D is derived from human breast cancer,and stably express firefly luciferase reporter gene under the control of the ER response element. This cell line is an ideal cellular model for monitoring the activation of Estrogen Receptor Signaling Pathway triggered by stimuli treatment, enforced gene expression and gene knockdown.

GAS Luciferase Reporter Lentivirus (IFN-γ/JAK/STAT1 Pathway)

78653 500 µl x 2
EUR 835
Description: The GAS Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by three copies of the interferon gamma (IFN-γ) activated sites (GAS) located upstream of the minimal TATA promoter and a puromycin selection gene for the selection of stable clones. After transduction, the GAS-regulated gene expression in the target cells can be monitored by measuring the luciferase activity.

ISRE Luciferase Reporter Lentivirus (JAK/STAT Signaling Pathway)

79824 500 µl x 2
EUR 820
Description: The JAK/STAT pathway is activated by various cytokines and growth factors and plays a critical role in cell growth, hematopoiesis, and immune response. In mammals, there are four JAKs (JAK1, JAK2, JAK3 and TYK2) and seven STAT proteins. IFNα is a Type I interferon. Binding of IFNα to its receptor leads to the activation of JAK1 and TYK2, which in turn phosphorylate and activate STAT1 and STAT2. The phosphorylated STAT1 and 2 form a heterodimer and bind to IRF9/p48, forming a protein complex ISGF3. This complex translocates to the nucleus and binds to the ISRE (Interferon Stimulated Response Element) in the promoter region, thereby promoting transcription of interferon-inducible genes.
The ISRE Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by multimerized ISRE response element located upstream of the minimal TATA promoter. After transduction, the activity of Type I interferon-induced JAK/STAT signaling pathway in the target cells can be monitored by measuring the luciferase activity.

Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)

79942-1 100 µl
EUR 875
Description: The SARS-CoV-2 Spike Pseudotyped Lentivirus were produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1) as the envelope glycoproteins instead of the commonly used VSV-G. These pseudovirions also contain the firefly luciferase gene driven by a CMV promoter, therefore, the spike-mediated cell entry can be conveniently measured via luciferase reporter activity. The SARS-CoV-2 Spike pseudotyped lentivirus can be used to measure the activity of neutralizing antibody against SARS-CoV-2 in a Biosafety Level 2 facility._x000D_ _x000D_

Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)

79942-2 500 µl x 2
EUR 4405
Description: The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of the viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting Enzyme 2 (ACE2) receptor found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. Drugs targeting the interaction between the Spike protein of SARS-CoV-2 and ACE2 may offer protection against the viral infection._x000D_The SARS-CoV-2 Spike Pseudotyped Lentivirus were produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1) as the envelope glycoproteins instead of the commonly used VSV-G. These pseudovirions also contain the firefly luciferase gene driven by a CMV promoter, therefore, the spike-mediated cell entry can be conveniently measured via luciferase reporter activity. The SARS-CoV-2 Spike pseudotyped lentivirus can be used to measure the activity of neutralizing antibody against SARS-CoV-2 in a Biosafety Level 2 facility._x000D_ _x000D_

Spike (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter)

78637-1 100 µl
EUR 795
Description: The Spike (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) was produced with SARS-CoV-2 Spike corresponding to the initial strain (Genbank Accession #QHD43416.1) as the envelope glycoprotein instead of VSV-G. The pseudovirions contain the firefly luciferase gene; therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 in a Biosafety Level 2 facility.The Spike (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) has been validated for use with target cells Vero-E6, Calu-3, and ACE2-HEK293 (BPS Bioscience #79951). Spike VSV Delta G are preferred for use in cells such as Vero-E6 and Calu-3.The infectivity of VSV-Delta G pseudotypes is restricted to a single round of replication, therefore the pseudotypes can be handled using BSL-2 containment practices.

Spike (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter)

78637-2 500 µl x 2
EUR 3995
Description: The Spike (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) was produced with SARS-CoV-2 Spike corresponding to the initial strain (Genbank Accession #QHD43416.1) as the envelope glycoprotein instead of VSV-G. The pseudovirions contain the firefly luciferase gene; therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 in a Biosafety Level 2 facility.The Spike (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) has been validated for use with target cells Vero-E6, Calu-3, and ACE2-HEK293 (BPS Bioscience #79951). Spike VSV Delta G are preferred for use in cells such as Vero-E6 and Calu-3.The infectivity of VSV-Delta G pseudotypes is restricted to a single round of replication, therefore the pseudotypes can be handled using BSL-2 containment practices.

TCF/LEF Luciferase Reporter Lentivirus (Wnt/β-catenin Signaling Pathway)

79787 500 µl x 2
EUR 875
Description: The TCF/LEF Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene under the control of TCF/LEF-responsive element located upstream of the minimal TATA promoter. After transduction, activation of the Wnt/β-catenin signaling pathway in the target cells can be monitored by measuring the luciferase activity.

Spike (D614G) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter)

78642-1 100 µl
EUR 795
Description: The Spike (D614G) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) was produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1; with D614G mutation) as the envelope glycoprotein instead of VSV-G. The pseudovirions contain the firefly luciferase gene; therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (D614G) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 D614G variant in a Biosafety Level 2 facility.The Spike (D614G) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) has been validated for use with target cells Vero-E6 and ACE2-HEK293 (BPS Bioscience #79951). Spike VSV Delta G is preferred over lentiviral-based spike pseudoviruses for use in cells such as Vero-E6 parental cells.

Spike (D614G) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter)

78642-2 500 µl x 2
EUR 3995
Description: The Spike (D614G) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) was produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1; with D614G mutation) as the envelope glycoprotein instead of VSV-G. The pseudovirions contain the firefly luciferase gene; therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (D614G) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 D614G variant in a Biosafety Level 2 facility.The Spike (D614G) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) has been validated for use with target cells Vero-E6 and ACE2-HEK293 (BPS Bioscience #79951). Spike VSV Delta G is preferred over lentiviral-based spike pseudoviruses for use in cells such as Vero-E6 parental cells.

Spike Variants (SARS-CoV-2) Pseudotyped Lentivirus Pack (Luciferase Reporter)

78616 12 x 100 µl
EUR 2795
Description: The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of the viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting Enzyme 2 (ACE2) receptor found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. Drugs targeting the interaction between the Spike protein of SARS-CoV-2 and human ACE2 may offer protection against the viral infection. Numerous SARS-CoV-2 variants have been identified so far. These variants contain a number of mutations that may increase morbidity and mortality and allow the virus to spread more easily and quickly than the original strain.BPS Bioscience has launched a series of Spike Variants (SARS-CoV-2) Pseudotyped Lentivirus (Luc reporter). The Spike (SARS-CoV-2) Pseudotyped Lentiviruses were produced with SARS-CoV-2 Spike Variant (see below for mutation details) as the envelope glycoproteins instead of the commonly used VSV-G. These pseudovirions contain the firefly luciferase gene driven by a CMV promoter, therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike Variants (SARS-CoV-2) Pseudotyped Lentivirus Pack (Luciferase Reporter) contains a collection of 12 Spike variants (SARS-CoV-2) Pseudotyped lentivirus (Luc reporter). It is a great tool to screen for variant-specific antibodies or to test the binding or efficacy of drug candidates against the different Spike variants. The Spike (SARS-CoV-2) pseudotyped lentiviruses can be used to measure the activity of neutralizing antibody against SARS-CoV-2 infection in a Biosafety Level 2 facility.

Spike (BA.1.1, Omicron Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter)-100 µl

78641-1 100 µl
EUR 795
Description: The Spike (BA.1.1, Omicron Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) was produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1 containing all the Omicron BA.1.1 mutations; see below for details) as the envelope glycoprotein instead of VSV-G. The pseudovirions contain the firefly luciferase gene; therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (BA.1.1 Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 BA.1.1 variant in a Biosafety Level 2 facility.As shown in Figures 1 and 2, the Spike (BA.1.1 Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) has been validated for use with target cells Vero-E6 and ACE2-HEK293 (BPS Bioscience #79951). Spike VSV Delta G is preferred over lentiviral-based spike pseudoviruses for use in cells such as Vero-E6 parental cells.Spike Mutations in BA.1.1 Omicron Variant:A67V, Δ69-70, G142D, Δ143-145, Δ211, L212I, ins214EPE, G339D, R346K, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, T95I, Q954H, N969K, L981F

Spike (B.1.617.2, Delta Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter)

78640-1 100 µl
EUR 795
Description: The Spike (B.1.617.2, Delta Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) was produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1 containing all the Delta B.1.617.2 mutations; see below for details) as the envelope glycoprotein instead of VSV-G. The pseudovirions contain the firefly luciferase gene; therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (BA.1.617.2 Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 B.1.617.2 variant in a Biosafety Level 2 facility.The Spike (B.1.617.2 Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) has been validated for use with target cells Vero-E6 and ACE2-HEK293 (BPS Bioscience #79951). Spike VSV Delta G is preferred over lentiviral-based Spike pseudoviruses for use in cells such as Vero-E6 parental cells.Spike Mutations in B.1.617.2 Delta Variant:T19R, G142D, del156/157, R158G, L452R, T478K, D614G, P681R, D950N

Spike (B.1.617.2, Delta Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter)

78640-2 500 µl x 2
EUR 3995
Description: The Spike (B.1.617.2, Delta Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) was produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1 containing all the Delta B.1.617.2 mutations; see below for details) as the envelope glycoprotein instead of VSV-G. The pseudovirions contain the firefly luciferase gene; therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (BA.1.617.2 Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 B.1.617.2 variant in a Biosafety Level 2 facility.The Spike (B.1.617.2 Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) has been validated for use with target cells Vero-E6 and ACE2-HEK293 (BPS Bioscience #79951). Spike VSV Delta G is preferred over lentiviral-based Spike pseudoviruses for use in cells such as Vero-E6 parental cells.Spike Mutations in B.1.617.2 Delta Variant:T19R, G142D, del156/157, R158G, L452R, T478K, D614G, P681R, D950N

Spike (BQ.1, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)

78697-1 100 µl
EUR 835
Description: The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of the viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting Enzyme 2 (ACE2) receptor found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. Drugs targeting the interaction between the Spike protein of SARS-CoV-2 and ACE2 may offer protection against the viral infection. Omicron Variant was identified in South Africa in November of 2021. This variant has a large number of mutations that allow the virus to spread more easily and quickly than other variants. As of May 2022, Omicron variants were divided into seven distinct sub-lineages: BA.1, BA.1.1, BA.2, BA.3, BA.2.12.1, BA.4, and BA.5. As of October 2022, several new BA.5 sub-lineages (e.g. BQ.1, BQ.1.1, BF.7) have been designated._x000D_The spike protein of BQ.1 omicron variant has additional mutations (K444T and N460K) based on the BA.5 variant. The Spike (BQ.1, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentiviruses were produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1 containing all the Omicron BQ.1 mutations; see below for details) as the envelope glycoprotein instead of the commonly used VSV-G. These pseudovirions contain the firefly luciferase gene driven by a CMV promoter (Figure 1), therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (BQ.1, Omicron Variant) (SARS-CoV-2) pseudovirus can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 Omicron BQ.1 variant in a Biosafety Level 2 facility._x000D_

_x000D_Figure 1. Schematic of the Luciferase Reporter in SARS-CoV-2 Spike Pseudovirion._x000D_As shown in Figures 2 and 3 in Validation Data, the Spike Omicron BQ.1 pseudovirus has been validated for use with ACE2-HEK293 target cells (which overexpress ACE2; BPS Bioscience #79951)._x000D_Spike Mutations in BQ.1 Omicron Variant:_x000D_Del69-70, T19I, LPPA24-27S, G142D, V213G, G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K

Spike (BQ.1, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)

78697-2 500 µl x 2
EUR 4195
Description: The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of the viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting Enzyme 2 (ACE2) receptor found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. Drugs targeting the interaction between the Spike protein of SARS-CoV-2 and ACE2 may offer protection against the viral infection. Omicron Variant was identified in South Africa in November of 2021. This variant has a large number of mutations that allow the virus to spread more easily and quickly than other variants. As of May 2022, Omicron variants were divided into seven distinct sub-lineages: BA.1, BA.1.1, BA.2, BA.3, BA.2.12.1, BA.4, and BA.5. As of October 2022, several new BA.5 sub-lineages (e.g. BQ.1, BQ.1.1, BF.7) have been designated._x000D_The spike protein of BQ.1 omicron variant has additional mutations (K444T and N460K) based on the BA.5 variant. The Spike (BQ.1, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentiviruses were produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1 containing all the Omicron BQ.1 mutations; see below for details) as the envelope glycoprotein instead of the commonly used VSV-G. These pseudovirions contain the firefly luciferase gene driven by a CMV promoter (Figure 1), therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (BQ.1, Omicron Variant) (SARS-CoV-2) pseudovirus can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 Omicron BQ.1 variant in a Biosafety Level 2 facility._x000D_

_x000D_Figure 1. Schematic of the Luciferase Reporter in SARS-CoV-2 Spike Pseudovirion._x000D_As shown in Figures 2 and 3 in Validation Data, the Spike Omicron BQ.1 pseudovirus has been validated for use with ACE2-HEK293 target cells (which overexpress ACE2; BPS Bioscience #79951)._x000D_Spike Mutations in BQ.1 Omicron Variant:_x000D_Del69-70, T19I, LPPA24-27S, G142D, V213G, G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K

Spike (BQ.1.1, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)

78698-1 100 µl
EUR 835
Description: The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of the viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting Enzyme 2 (ACE2) receptor found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. Drugs targeting the interaction between the Spike protein of SARS-CoV-2 and ACE2 may offer protection against the viral infection. Omicron Variant was identified in South Africa in November of 2021. This variant has a large number of mutations that allow the virus to spread more easily and quickly than other variants. As of May 2022, Omicron variants were divided into seven distinct sub-lineages: BA.1, BA.1.1, BA.2, BA.3, BA.2.12.1, BA.4, and BA.5. As of October 2022, several new BA.5 sub-lineages (e.g. BQ.1, BQ.1.1, BF.7) have been designated._x000D_The spike protein of BQ.1.1 omicron variant has additional mutations (R346T, K444T and N460K) based on the BA.5 variant. The Spike (BQ.1.1, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentiviruses were produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1 containing all the Omicron BQ.1.1 mutations; see below for details) as the envelope glycoprotein instead of the commonly used VSV-G. These pseudovirions contain the firefly luciferase gene driven by a CMV promoter (Figure 1), therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (BQ.1.1, Omicron Variant) (SARS-CoV-2) pseudovirus can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 Omicron BQ.1.1 variant in a Biosafety Level 2 facility._x000D_

_x000D_Figure 1. Schematic of the Luciferase Reporter in SARS-CoV-2 Spike Pseudovirion_x000D_As shown in Figures 2 and 3 in Validation Data, the Spike Omicron BQ.1.1 pseudovirus has been validated for use with ACE2-HEK293 target cells (which overexpress ACE2; BPS Bioscience #79951)._x000D_Spike Mutations in BQ.1.1 Omicron Variant:_x000D_Del69-70, T19I, LPPA24-27S, G142D, V213G, G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K

Spike (BQ.1.1, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)

78698-2 500 µl x 2
EUR 4195
Description: The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of the viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting Enzyme 2 (ACE2) receptor found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. Drugs targeting the interaction between the Spike protein of SARS-CoV-2 and ACE2 may offer protection against the viral infection. Omicron Variant was identified in South Africa in November of 2021. This variant has a large number of mutations that allow the virus to spread more easily and quickly than other variants. As of May 2022, Omicron variants were divided into seven distinct sub-lineages: BA.1, BA.1.1, BA.2, BA.3, BA.2.12.1, BA.4, and BA.5. As of October 2022, several new BA.5 sub-lineages (e.g. BQ.1, BQ.1.1, BF.7) have been designated._x000D_The spike protein of BQ.1.1 omicron variant has additional mutations (R346T, K444T and N460K) based on the BA.5 variant. The Spike (BQ.1.1, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentiviruses were produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1 containing all the Omicron BQ.1.1 mutations; see below for details) as the envelope glycoprotein instead of the commonly used VSV-G. These pseudovirions contain the firefly luciferase gene driven by a CMV promoter (Figure 1), therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (BQ.1.1, Omicron Variant) (SARS-CoV-2) pseudovirus can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 Omicron BQ.1.1 variant in a Biosafety Level 2 facility._x000D_

_x000D_Figure 1. Schematic of the Luciferase Reporter in SARS-CoV-2 Spike Pseudovirion_x000D_As shown in Figures 2 and 3 in Validation Data, the Spike Omicron BQ.1.1 pseudovirus has been validated for use with ACE2-HEK293 target cells (which overexpress ACE2; BPS Bioscience #79951)._x000D_Spike Mutations in BQ.1.1 Omicron Variant:_x000D_Del69-70, T19I, LPPA24-27S, G142D, V213G, G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K

Spike (BF.7, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)

78699-1 100 µl
EUR 835
Description: The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of the viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting Enzyme 2 (ACE2) receptor found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. Drugs targeting the interaction between the Spike protein of SARS-CoV-2 and ACE2 may offer protection against the viral infection. Omicron Variant was identified in South Africa in November of 2021. This variant has a large number of mutations that allow the virus to spread more easily and quickly than other variants. As of May 2022, Omicron variants were divided into seven distinct sub-lineages: BA.1, BA.1.1, BA.2, BA.3, BA.2.12.1, BA.4, and BA.5. As of October 2022, several new BA.5 sub-lineages (e.g. BQ.1, BQ.1.1, BF.7) have been designated._x000D_The spike protein of BF.7 omicron variant has additional mutation R346T based on the BA.5 variant. The Spike (BF.7, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentiviruses were produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1 containing all the Omicron BF.7 mutations; see below for details) as the envelope glycoprotein instead of the commonly used VSV-G. These pseudovirions contain the firefly luciferase gene driven by a CMV promoter (Figure 1), therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (BF.7, Omicron Variant) (SARS-CoV-2) pseudovirus can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 Omicron BF.7 variant in a Biosafety Level 2 facility._x000D_

_x000D_Figure 1. Schematic of the Luciferase Reporter in SARS-CoV-2 Spike Pseudovirion._x000D_As shown in Figures 2 and 3 in Validation Data, the Spike Omicron BF.7 pseudovirus has been validated for use with ACE2-HEK293 target cells (which overexpress ACE2; BPS Bioscience #79951)._x000D_Spike Mutations in BF.7 Omicron Variant:_x000D_Del69-70, T19I, LPPA24-27S, G142D, V213G, G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K

Spike (BF.7, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)

78699-2 500 µl x 2
EUR 4195
Description: The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of the viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting Enzyme 2 (ACE2) receptor found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. Drugs targeting the interaction between the Spike protein of SARS-CoV-2 and ACE2 may offer protection against the viral infection. Omicron Variant was identified in South Africa in November of 2021. This variant has a large number of mutations that allow the virus to spread more easily and quickly than other variants. As of May 2022, Omicron variants were divided into seven distinct sub-lineages: BA.1, BA.1.1, BA.2, BA.3, BA.2.12.1, BA.4, and BA.5. As of October 2022, several new BA.5 sub-lineages (e.g. BQ.1, BQ.1.1, BF.7) have been designated._x000D_The spike protein of BF.7 omicron variant has additional mutation R346T based on the BA.5 variant. The Spike (BF.7, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentiviruses were produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1 containing all the Omicron BF.7 mutations; see below for details) as the envelope glycoprotein instead of the commonly used VSV-G. These pseudovirions contain the firefly luciferase gene driven by a CMV promoter (Figure 1), therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (BF.7, Omicron Variant) (SARS-CoV-2) pseudovirus can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 Omicron BF.7 variant in a Biosafety Level 2 facility._x000D_

_x000D_Figure 1. Schematic of the Luciferase Reporter in SARS-CoV-2 Spike Pseudovirion._x000D_As shown in Figures 2 and 3 in Validation Data, the Spike Omicron BF.7 pseudovirus has been validated for use with ACE2-HEK293 target cells (which overexpress ACE2; BPS Bioscience #79951)._x000D_Spike Mutations in BF.7 Omicron Variant:_x000D_Del69-70, T19I, LPPA24-27S, G142D, V213G, G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K

Transgenic crops have been additionally remodeled with genes from numerous species for drought tolerance. The UK (principally with transgenesis and site-specific nucleases) and France (with no transgenic instruments however with MAS and site-specific nucleases) are the primary nations finishing up analysis applications for each biotic stress and drought tolerance. Thus, few European nations used transgenesis for gluten protein composition and RNAi-mediated silencing in celiac illness. Because of vandalism discipline trials of transgenics dropped since 2000. No transgenic wheat is cultivated in Europe for political causes.

Biotech crop planting resumes high adoption in 2016.

Biotech crop planting resumes high adoption in 2016.

The world space of biotech crops in 2016 elevated from 179.7 million hectares to 185.1 million hectares, a 3% improve equal to five.four million hectares. Some 26 nations planted biotech crops, 19 of which had been creating nations and 7 had been industrial. Information and knowledge collected from numerous credible sources confirmed variations from the earlier yr. Fluctuations in biotech crop space (each will increase and reduces) are influenced by elements together with, amongst others, acceptance and commercialization of recent merchandise, demand for meat and livestock feeds, climate situations, world market value, illness/pest stress, and authorities’s enabling insurance policies.

Countries which have elevated biotech crop space in lowering order in 2016 had been Brazil, United States of America, Canada, South Africa, Australia, Bolivia, Philippines, Spain, Vietnam, Bangladesh, Colombia, Honduras, Chile, Sudan, Slovakia, and Costa Rica. Countries with decreased biotech space in lowering order had been China, India, Argentina, Paraguay, Uruguay, Mexico, Portugal, and Czech Republic, in lowering incremental lower in biotech space. Pakistan and Myanmar had been the one nations with no change in biotech crop (cotton) planted. Information detailed in the paper together with future crops and traits in every nation may information stakeholders in knowledgeable crafting of methods and insurance policies for elevated adoption of biotech crops in the nation.

In Switzerland, the chemical, pharma and biotech industries make a considerable and sustained contribution to the Swiss financial system. The firm members of scienceindustries make use of round 70,000 folks in Switzerland. Since 1980 worth creation and productiveness have elevated markedly. As a end result the share of the Swiss gross worth added has grown regularly to achieve 5.6% in 2015. Exports have additionally elevated. Today the chemical, pharma and biotech business contributes round 45% of all Swiss exports and is subsequently the biggest Swiss export business.

Neuro-oncology biotech business progress report.

The Brain Tumor Biotech Center on the Feinstein Institute for Medical Research, in collaboration with Voices Against Brain Cancer hosted The Brain Tumor Biotech Summit at in New York City in June 2015. The focus was as soon as once more on fostering collaboration between neuro-oncologist, neurosurgeons, scientists, leaders from biotechnology and pharmaceutical industries, and members of the monetary group. The summit highlighted the latest advances in the therapy of mind tumor, and particularly centered on concentrating on of stem cells and EGFR, use of prophage and immunostimulatory vaccines, retroviral vectors for drug supply, biologic prodrug, Cesium brachytherapy, and use of electrical subject to disrupt tumor cell proliferation. This article summarizes the present progress in mind tumor analysis as offered at 2015 The Brain Tumor Biotech Summit.

Almost 200 scientists and professionals from academia and business attended the BioTech 2017 convention on the Zurich University of Applied Sciences (ZHAW) in Wädenswil on 7./8. September 2017. The focus of this yr’s convention was (bio) course of analytics and sensor expertise, taking into consideration the more and more outstanding position of on-line measurement and management in the method business. Acute respiratory infections place an enormous burden on society in phrases of incapacity, untimely mortality, and in addition direct well being service prices (medicine prescriptions) and the oblique prices associated to misplaced manufacturing. Therefore, prevention of respiratory infections is a vital purpose for public well being interventions.

In this context, silver nanoparticles (AgNPs) signify an attention-grabbing perspective for analysis and improvement by advantage of their favorable antimicrobial exercise towards many respiratory pathogens. One of the newest improvements in the biotech subject mentioned in this assessment is the creation of a biocompatible, biogel-based nasal filter enriched with AgNPs. Compared to conventional private protecting tools (PPE), such a nasal filter has the benefit of mixing the antibacterial and antiviral exercise of AgNPs with the frequent filtration capability shared by different PPEs.

This twin mechanism implies that AgNP-enriched nasal filters serve to cut back the infecting microbial-load and shield the decrease airways, with out interfering with the conventional respiratory capability (airflow-resistance <5%). Given their antimicrobial traits and efficiency, AgNP-enriched nasal filters can meet many group and occupational presently unmet wants in the prevention of airborne infectious illnesses, by guaranteeing a wonderful respiratory-comfort and a steady day-use. This article describes the important thing necessities from the point of view of the chemical-pharma business in order that Switzerland can proceed to compete as an revolutionary location in world competitors.

 Biotech crop planting resumes high adoption in 2016.

Careers at Biotech Start-Ups and in Entrepreneurship.

The world of biotechnology “start-ups” and entrepreneurship affords thrilling new avenues for driving state-of-the-art analysis utilizing an arsenal of multidisciplinary expertise, whether or not your position is as a part of a workforce or as a pacesetter. Although historically these positions might not be as safe as these provided by among the bigger firms, the small start-up tradition offers alternatives for contributing at many ranges to a variety of tasks: from scientific discovery to supply of proof of idea and mental property; from evaluation of market alternatives and aggressive intelligence to creation of time strains and enterprise plans for a primary product.

Creatine Kinase Assay Kit

abx098420-Toshiba40R140ml2R220ml1 Toshiba 40; R1: 40ml×2 R2: 20ml×1
EUR 303.6

Creatine Kinase Assay Kit

abx298811-100Assays 100 Assays
EUR 830.4

Creatine Kinase Assay Kit

Z5030048 100 assays
EUR 1020

EnzyChrom™ Creatine Assay Kit

ECRT-100 100
EUR 429
Description: For quantitative determination of creatine and evaluation of drug effects on creatine metabolism. Key Features: High sensitivity and wide linear range. Use 10 µL sample. Linear detection range 4 to 1000 µM (colorimetric) or 0.5 to 50 µM (fluorimetric). Homogeneous and simple procedure. Simple "mix-and-measure" procedure allows reliable quantitation of creatine within 30 minutes. Method: OD570nm, or FL530/590nm. Samples: Serum, plasma, urine, saliva etc. Species: All. Procedure: Assay takes 30 min. Kit size: 100 tests. Detection limit: 4 µM.

Creatine Microplate Assay Kit

DLSM0170 100 Assays
EUR 245
Description: Detection and Quantification of Creatine Content.

RealQuant Creatine Kinase Assay Kit

C0600-010 100 Assays
EUR 1323.6

Creatine Kinase Microplate Assay Kit

DLSM0045 100 Assays
EUR 682.5
Description: Detection and Quantification of Creatine Kinase Activity.

Creatine Kinase Isoenzyme MB Assay Kit

abx098421-Hitachi7060R160ml8R260ml2 Hitachi 7060; R1: 60ml×8 R2: 60ml×2
EUR 284.4

Creatine Kinase Isoenzyme MB Assay Kit

abx098421-Hitachi7170R124ml1R26ml1 Hitachi 7170; R1: 24ml×1 R2: 6ml×1
EUR 284.4

Creatine Kinase Isoenzyme MB Assay Kit

abx098421-Hitachi7170R140ml2R220ml1 Hitachi 7170; R1: 40ml×2 R2: 20ml×1
EUR 453.6

Creatine Kinase Isoenzyme MB Assay Kit

abx098421-Hitachi7170R160ml1R215ml1 Hitachi 7170; R1: 60ml×1 R2: 15ml×1
EUR 397.2

EnzyChrom™ Creatine Kinase Assay Kit

ECPK-100 100
EUR 519
Description: For quantitative determination of creatine kinase (CK) activity and evaluation of drug effects on CK activity. Key Features: Sensitive and accurate. Detection range: 5 to 300 U/L creatine kinase in 96-well plate assay. Convenient. The procedure involves adding a single working reagent, and reading the optical density at 20 min and 40 min at room temperature or 37°C. High-throughput. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: OD340nm. Samples: Serum, plasma etc. Species: All. Procedure: Assay takes 40 min. Kit size: 100 tests. Detection limit: 5 U/L.

Creatine Colorimetric/Fluorometric Assay Kit

K635-100 each
EUR 574.8

Creatine Colorimetric/Fluorometric Assay Kit

K2137-100 100 assays
EUR 602.4

Creatine Kinase (CK) Activity Colorimetric Assay Kit

K777-100 each
EUR 718.8

Creatine Transporter (CRT) Magnetic Luminex Assay Kit

LKU605685-96T 96T
EUR 966

Creatine Kinase, Muscle (CKM) Magnetic Luminex Assay Kit

LKU605445-96T 96T
EUR 869.4

Creatine Kinase, Muscle (CKM) Magnetic Luminex Assay Kit

LKU605452-96T 96T
EUR 894.7

Creatine Kinase, Muscle (CKM) Magnetic Luminex Assay Kit

LKU605457-96T 96T
EUR 944.2

Creatine Kinase, Muscle (CKM) Magnetic Luminex Assay Kit

LKU605463-96T 96T
EUR 944.2

Creatine Kinase, Muscle (CKM) Magnetic Luminex Assay Kit

LKU605469-96T 96T
EUR 1043.1

Creatine Kinase B (CK-BB) Magnetic Luminex Assay Kit

LKU605659-96T 96T
EUR 993.6

Creatine Kinase B (CK-BB) Magnetic Luminex Assay Kit

LKU605665-96T 96T
EUR 966

Creatine Kinase B (CK-BB) Magnetic Luminex Assay Kit

LKU605669-96T 96T
EUR 1048.8

CheKine™ Micro Creatine Kinase (CK) Activity Assay Kit

KTB1012-48T 48 T
EUR 279
Description: CheKine™ Micro Creatine Kinase (CK) Activity Assay Kit is designed to detect the Creatine Kinase (CK) Activity in the sample.

CheKine™ Micro Creatine Kinase (CK) Activity Assay Kit

KTB1012-96T 96 T
EUR 479
Description: CheKine™ Micro Creatine Kinase (CK) Activity Assay Kit is designed to detect the Creatine Kinase (CK) Activity in the sample.

Creatine Kinase MB Isoenzyme (CKMB) Magnetic Luminex Assay Kit

LKU605672-96T 96T
EUR 794.7

Creatine Kinase MB Isoenzyme (CKMB) Magnetic Luminex Assay Kit

LKU605677-96T 96T
EUR 839.5

Creatine Kinase MB Isoenzyme (CKMB) Magnetic Luminex Assay Kit

LKU605680-96T 96T
EUR 869.4

Creatine Kinase, Mitochondrial 1A (CKMT1A) Magnetic Luminex Assay Kit

LKU603429-96T 96T
EUR 869.4

Creatine Kinase, Mitochondrial 2, Sarcomeric (CKMT2) Magnetic Luminex Assay Kit

LKU603432-96T 96T
EUR 966

Creatinine Assay Kit

abx098422-Hitachi7020R150ml3R250ml1 Hitachi 7020; R1: 50ml×3 R2: 50ml×1
EUR 622.8

Creatinine Assay Kit

abx098422-Hitachi7060R190ml2R260ml1 Hitachi 7060; R1: 90ml×2 R2: 60ml×1
EUR 566.4

Creatinine Assay Kit

abx098422-Toshiba120R140ml3R240ml1 Toshiba 120; R1: 40ml×3 R2: 40ml×1
EUR 679.2

Creatinine Assay Kit

abx098422-Toshiba120R150ml3R250ml1 Toshiba 120; R1: 50ml×3 R2: 50ml×1
EUR 622.8

Creatinine Assay Kit

abx098422-Toshiba40R150ml3R250ml1 Toshiba 40; R1: 50ml×3 R2: 50ml×1
EUR 622.8

Creatinine Assay Kit

55R-1467 100 assays
EUR 765.6
Description: Assay Kit for detection of Creatinine in the research laboratory

Creatinine Assay Kit

Z5030020 500 assays
EUR 636

Creatinine Assay Kit

6041 1 kit
EUR 106
Description: Urine, Serum, Culture Media

Urinary Creatinine Assay Kit

STA-378 192 assays
EUR 518.4
Description: Cell Biolabs? Creatinine Assay Kit measures creatinine levels in urine. Samples are compared to a known concentration of creatinine standard within a 96-well microtiter plate format. Samples and standards are incubated for 30 minutes with a reaction reagent which changes color from yellow to bright orange upon reacting with creatinine, forming the creatinine-picrate complex. The plate is read with a standard 96-well spectrophotometric microplate reader at 490 nm. Higher OD values correlate with high creatinine concentrations. Sample creatinine concentrations are determined by comparison with the known creatinine standards.

Urinary Creatinine Assay Kit

UCR1 1 Kit
EUR 164.4

RealQuant Creatinine Assay Kit

C0500-050 500 Assays
EUR 999.6

Creatinine Microplate Assay Kit

DLSM0202 100 Assays
EUR 245
Description: Detection and Quantification of Creatinine Content.

EnzyChrom™ Creatinine Assay Kit

E2CT-100 100
EUR 399
Description: For quantitative determination of creatinine and evaluation of drug effects on its metabolism. Key Features: Fast and sensitive. Linear detection range: 4.8 to 500 µM or 0.054-5.7 mg/dL (colorimetric assay) and 0.25 to 100 µM or 0.0028-1.14 mg/dL (fluorimetric assay) for a 60 min reaction. It is 3- and 53-fold more sensitive than the traditional Jaffe method (e.g. DICT-500), especially useful for small samples or where high sensitivity is required. Convenient. The procedure involves adding a single working reagent and reading after 60 minutes. Room temperature assay. No 37°C heater is needed. High-throughput. Homogeneous "mix-incubate-measure" type assay. Can be readily automated to process thousands of samples per day. Method: OD570nm; FL530/585nm. Samples: Urine, serum, plasma, and other biological preparations. Species: All. Procedure: 60 min. Size: 100 tests. Detection Limit: Colorimetric assay: 4.8 µM or 0.054 mg/dL; Fluorimetric assay: 0.25 µM or 0.0028 mg/dL.

QuantiChrom™ Creatinine Assay Kit

DICT-500 500
EUR 399
Description: For quantitative determination of creatinine and evaluation of drug effects on creatinine metabolism. Key Features: Sensitive and accurate. Use 30 µL samples. Detection limit 0.10 mg/dL (8 µM) creatinine in 96-well plate assay. Simple and high-throughput. The procedure involves addition of a single working reagent and incubation for 5 min. Can be automated as a high-throughput assay for thousands of samples per day. Improved reagent stability and versatility. The optimized formulation has greatly enhanced reagent and signal stability. Assays can be executed in 96-well plate or cuvet. Low interference in biological samples. No pretreatments are needed. Assays can be directly performed on raw biological samples. Method: OD510nm. Samples: Urine, serum, plasma and biological preparations. Species: All. Procedure: Assay takes 20 min. Kit size: 500 tests. Detection limit: 0.1 mg/dL (8 µM).

Urinary Creatinine Assay Kit (5 kit size)

UCR5 5 Kits
EUR 409.2

Cr(Creatinine) Assay Kit(Colorimetric)

EKF60677-48T 48T
EUR 396.9

Cr(Creatinine) Assay Kit(Colorimetric)

EKF60677-5x96T 5x96T
EUR 2693.25

Cr(Creatinine) Assay Kit(Colorimetric)

EKF60677-96T 96T
EUR 567

Human Creatine kinase MT AssayLite Antibody (RPE Conjugate)

33406-05151 150 ug
EUR 513.6

Human Creatine kinase MT AssayLite Antibody (APC Conjugate)

33406-05161 150 ug
EUR 513.6

Human Creatine kinase MT AssayLite Antibody (FITC Conjugate)

33406-05141 150 ug
EUR 513.6

Human Creatine kinase MT AssayLite Antibody (PerCP Conjugate)

33406-05171 150 ug
EUR 565.2

GWB-AXR295-100T - Creatinine Assay Kit

GWB-AXR295-100T 100assays
EUR 619

Rat Creatine ELISA kit

E01A12800 96T
EUR 700
Description: ELISA

Creatine

HY-W010388 5g
EUR 142.8

Creatine

591967 50.0g
EUR 260

Creatine

T4883-10mg 10mg Ask for price
Description: Creatine

Creatine

T4883-1g 1g Ask for price
Description: Creatine

Creatine

T4883-1mg 1mg Ask for price
Description: Creatine

Creatine

T4883-50mg 50mg Ask for price
Description: Creatine

Creatine

T4883-5mg 5mg Ask for price
Description: Creatine

Creatinine (CTN) Magnetic Luminex Assay Kit

LKU605409-96T 96T
EUR 1186.8

Human Creatine Kinase type B AssayLite Antibody (RPE Conjugate)

32981-05151 150 ug
EUR 513.6

Human Creatine Kinase type B AssayLite Antibody (APC Conjugate)

32981-05161 150 ug
EUR 513.6

Goat Creatine ELISA kit

E01A47710 96T
EUR 700
Description: ELISA

Human Creatine Kinase type B AssayLite Antibody (FITC Conjugate)

32981-05141 150 ug
EUR 513.6

Human Creatine ELISA kit

E01A4037 96T
EUR 700
Description: ELISA

Mouse Creatine ELISA kit

E01A21541 96T
EUR 700
Description: ELISA

Sheep Creatine ELISA kit

E01A100004 96T
EUR 700
Description: ELISA

Human Creatine Kinase type B AssayLite Antibody (PerCP Conjugate)

32981-05171 150 ug
EUR 565.2

Rabbit Creatine ELISA kit

E01A30278 96T
EUR 700
Description: ELISA

Monkey Creatine ELISA kit

E01A73856 96T
EUR 700
Description: ELISA

Bovine Creatine ELISA kit

E01A82575 96T
EUR 700
Description: ELISA

Canine Creatine ELISA kit

E01A65142 96T
EUR 700
Description: ELISA

Chicken Creatine ELISA kit

E01A91297 96T
EUR 700
Description: ELISA

Porcine Creatine ELISA kit

E01A56427 96T
EUR 700
Description: ELISA

Creatinine Colorimetric/Fluorometric Assay Kit

K625-100 each
EUR 561.6

Creatinine Colorimetric/Fluorometric Assay Kit

K2130-100 100 assays
EUR 536.4

Human Creatine Kinase B-type (CKBB) AssayLite Antibody (RPE Conjugate)

11271-05051 150 ug
EUR 513.6

Human Creatine Kinase B-type (CKBB) AssayLite Antibody (APC Conjugate)

11271-05061 150 ug
EUR 513.6

Human Creatine Kinase M-type (CKMM) AssayLite Antibody (RPE Conjugate)

11281-05051 150 ug
EUR 513.6

Human Creatine Kinase M-type (CKMM) AssayLite Antibody (APC Conjugate)

11281-05061 150 ug
EUR 513.6

Human Creatine Kinase B-type (CKBB) AssayLite Antibody (FITC Conjugate)

11271-05041 150 ug
EUR 513.6

Human Creatine Kinase B-type (CKBB) AssayLite Antibody (PerCP Conjugate)

11271-05071 150 ug
EUR 565.2

Human Creatine Kinase M-type (CKMM) AssayLite Antibody (FITC Conjugate)

11281-05041 150 ug
EUR 513.6

Human Creatine Kinase M-type (CKMM) AssayLite Antibody (PerCP Conjugate)

11281-05071 150 ug
EUR 565.2

The Creatinine Companion (Creatinine Assay)

1012 -
EUR 410
Description: Nephrology ELISA

QuantiChrom™ Protein Creatinine Ratio Assay Kit

DPCR-100 100
EUR 599
Description: For quantitative determination of urinary protein and creatinine concentrations (protein/creatinine ratio, UPCR). Key Features: Sensitive and accurate. Use 20 µL samples. Linear detection range in 96-well plate: 1 - 20 mg/dL Protein and 1 - 150 mg/dL Creatinine. Fast and convenient. No sample pre-treatment is needed. Simple 10- minute "add-incubate-read" procedure. High-throughput adaptable. The procedure can be readily automated for processing thousands of samples per day. Method: OD600 and OD530nm. Samples: Urine samples. Species: All. Procedure: Assay takes 10 min. Kit size: 100 tests. Detection limit: 1 mg/dL Protein and 1 mg/dL Creatinine.

Rat Creatine Kinase ELISA kit

E02C2511-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Creatine Kinase ELISA kit

E02C2511-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Creatine Kinase ELISA kit

E02C2511-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Creatine Kinase ELISA kit

E08C2511-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Creatine Kinase ELISA kit

E08C2511-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Creatine Kinase ELISA kit

E08C2511-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Creatine Kinase ELISA kit

E07C2511-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Creatine Kinase ELISA kit

E07C2511-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Creatine Kinase ELISA kit

E07C2511-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Creatine Kinase ELISA kit

E01A12726 96T
EUR 700
Description: ELISA

Guinea Pig Creatine ELISA kit

E01A38992 96T
EUR 700
Description: ELISA

Goat Creatine Kinase ELISA kit

E06C2511-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Creatine Kinase ELISA kit

E06C2511-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Creatine Kinase ELISA kit

E06C2511-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Creatine Kinase ELISA kit

E01A47638 96T
EUR 700
Description: ELISA

Mouse Creatine Kinase ELISA kit

E03C2511-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Creatine Kinase ELISA kit

E03C2511-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Creatine Kinase ELISA kit

E03C2511-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Creatine Kinase ELISA kit

E01C2511-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Creatine Kinase ELISA kit

E01C2511-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Creatine Kinase ELISA kit

E01C2511-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Creatine Kinase ELISA kit

ELA-E2030m 96 Tests
EUR 1038

Sheep Creatine Kinase ELISA kit

E01A99932 96T
EUR 700
Description: ELISA

Human Creatine Kinase ELISA kit

E01A3965 96T
EUR 700
Description: ELISA

Mouse Creatine Kinase ELISA kit

E01A21467 96T
EUR 700
Description: ELISA

Creatine hydrate

CB0326 100g
EUR 73.57

Rat Creatine Phosphate ELISA kit

E02C0083-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Creatine Phosphate in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Creatine Phosphate ELISA kit

E02C0083-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Creatine Phosphate in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Creatine Phosphate ELISA kit

E02C0083-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Creatine Phosphate in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Creatine Phosphate ELISA kit

E08C0083-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Creatine Phosphate in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Creatine Phosphate ELISA kit

E08C0083-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Creatine Phosphate in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Creatine Phosphate ELISA kit

E08C0083-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Creatine Phosphate in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Creatine Kinase ELISA kit

E04C2511-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Creatine Kinase ELISA kit

E04C2511-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Creatine Kinase ELISA kit

E04C2511-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Creatine Kinase ELISA kit

E09C2511-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Creatine Kinase ELISA kit

E09C2511-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Creatine Kinase ELISA kit

E09C2511-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Creatine Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Creatine Phosphate ELISA kit

E07C0083-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Creatine Phosphate in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Creatine Phosphate ELISA kit

E07C0083-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Creatine Phosphate in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Creatine Phosphate ELISA kit

E07C0083-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Creatine Phosphate in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Creatine Kinase ELISA kit

E01A30205 96T
EUR 700
Description: ELISA

Monkey Creatine Kinase ELISA kit

E01A73784 96T
EUR 700
Description: ELISA

Bovine Creatine Kinase ELISA kit

E01A82503 96T
EUR 700
Description: ELISA

Canine Creatine Kinase ELISA kit

E01A65070 96T
EUR 700
Description: ELISA

Rat Creatine Phosphate ELISA kit

E01A10890 96T
EUR 700
Description: ELISA

Creatine riboside

563021 25.0mg
EUR 450

Creatine riboside

T15011-10mg 10mg Ask for price
Description: Creatine riboside

Creatine riboside

T15011-1g 1g Ask for price
Description: Creatine riboside

Creatine riboside

T15011-1mg 1mg Ask for price
Description: Creatine riboside

Creatine riboside

T15011-50mg 50mg Ask for price
Description: Creatine riboside

Creatine riboside

T15011-5mg 5mg Ask for price
Description: Creatine riboside

Goat Creatine Phosphate ELISA kit

E06C0083-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Creatine Phosphate in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Creatine Phosphate ELISA kit

E06C0083-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Creatine Phosphate in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Creatine Phosphate ELISA kit

E06C0083-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat Creatine Phosphate in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Chicken Creatine Kinase ELISA kit

E01A91225 96T
EUR 700
Description: ELISA

Goat Creatine Phosphate ELISA kit

E01A45802 96T
EUR 700
Description: ELISA

Often, should you get in on the bottom stage, you get to validate your personal idea, pitch to potential traders, argue worth, construct a workforce, interact advisors, after which, with funding in hand, launch a completely new analysis and improvement (R&D) enterprise. Many of the abilities and far of the expertise gained whereas pursuing a graduate diploma may be put to good use in these arenas as nicely. This path, nonetheless, shouldn’t be for the faint of coronary heart; it requires not solely a powerful scientific background and organizational expertise, but in addition the power to work nicely on a workforce, wonderful communication expertise, and persistence when confronted with delays or disappointment. With rising tasks in the small firm come the necessities for aptitudes for management, strategic and monetary planning, networking, negotiating, and managing each initiatives and personnel.

Chemistry, sustainability and naturality of perfumery biotech ingredients

Chemistry, sustainability and naturality of perfumery biotech ingredients

White biotechnology has emerged in biochemical manufacturing processes to ship perfumery ingredients satisfying novel pursuits of the society for pure, eco-responsible and sustainable supplies. As a consequence, an intense R&D exercise has taken place on these topics, leading to each scientific publications and patent functions reporting combos of state-of-the-art approaches in biocatalysis, metabolic engineering, artificial biology, biosynthesis elucidation, gene version and cloning, and analytical chemistry.

In this minireview, we current a smelly choice of novel biotechnological processes and ingredients from a scientific articles and patents survey protecting the final 6 years and analysed in phrases of chemistry, sustainability and naturalitysynthesis of important oil surrogates or single molecule ingredients, and on one other aspect the optimisation of properties of pure advanced substances by particular and selective enzymatic modifications of their chemical composition. Data had been confirmed, even evaluating luggage based on filling quantity. Data introduced on this research help the conclusion that CryoMACS freezing luggage are bioequivalent to Maco Biotech Freezing-EVA Bags for HPC cryopreservation.

The growing discoveries concerning the biology and capabilities of platelets within the final decade undoubtedly present that these cells are one of probably the most biotechnological human cells. This evaluate summarizes new advances in platelet biology, capabilities, and new ideas of biotech-educated platelets that join superior biomimetic science to platelet-based additive manufacturing for tissue regeneration. As extremely responsive and secretory cells, platelets may very well be explored to develop options that alter injured microenvironments by platelet-based artificial biomaterials with instructive extracellular cues for morphogenesis in tissue engineering past tissue regeneration 2.0.

Comparison of CryoMACS Freezing Bags with Maco Biotech Freezing-Ethinyl Vinyl Acetate Bags for Hematopoietic Progenitor Cells Cryopreservation Using a CD34 +-Enriched Product

Hematopoietic progenitor cells (HPCs) cryopreservation have functions, particularly within the autologous setting, permitting therapeutic use a number of years after assortment. Cryopreservation goals to protect the therapeutic properties of HPCs, and profitable cryopreservation will depend on a number of elements akin to preservation procedures, biopreservation media, freezing charges, and thawing procedures. In this context, the selection of the freezing bag is important because it offers mechanical safety through the freezing course of. Since Maco Biotech Freezing-ethinyl vinyl acetate (EVA) Bags® are now not obtainable in our nation, a comparative research was developed to confirm bioequivalence with the Miltenyi CryoMACS® freezing bag.

In this research, a CD34+-enriched product was used to higher reproduce HPC apheresis. Freezing luggage had been crammed with the identical quantity, cryopreserved with managed price freezing, and saved within the vapor part of liquid nitrogen for no less than 6 months. After thawing, all luggage had been examined for . Classification has been made between metabolic engineering on one aspect, permitting both biotechnological  integrity and sterility utilizing a microbial problem. In addition, a comparability was developed by evaluating restoration of white blood cells, mononuclear cells, lymphocytes, and CD34+ cells.No important variations between the 2 producers’ luggage have been noticed in phrases of the evaluated parameters.

This mini-review offers a perspective of conventional, rising and future functions of lactic acid micro organism (LAB) and how genome modifying instruments can be utilized to beat present challenges in all these functions. It additionally describes obtainable instruments and how these might be additional developed, and takes present laws under consideration. Genome modifying instruments are obligatory for the development of strains for brand spanking new functions and merchandise, however may play an important function in conventional ones, akin to meals and probiotics, as a analysis software for gaining mechanistic insights and discovering new properties.

Traditionally, recombinant DNA methods for LAB have strongly centered on being food-grade, however they lack velocity and the quantity of genetically tractable strains continues to be reasonably restricted. Further software growth will allow fast building of a number of mutants or mutant libraries on a genomic degree in all kinds of LAB strains. We additionally suggest an iterative Design-Build-Test-Learn workflow cycle for LAB cell manufacturing facility growth based mostly on techniques biology, with ‘cell manufacturing facility’ increasing past its conventional which means of manufacturing strains and making use of genome modifying instruments to advance LAB understanding, functions and pressure growth.

 Chemistry, sustainability and naturality of perfumery biotech ingredients

Microbe Profile: Komagataella phaffii: a methanol devouring biotech yeast previously generally known as Pichia pastoris

Methylotrophic yeasts of the genus Komagataella are abundantly present in tree exudates. Their potential to make the most of methanol as carbon and power supply depends on an assimilation pathway localized in largely expanded peroxisomes, and a cytosolic methanol dissimilation pathway. Other substrates like glucose or glycerol are readily utilized as effectively. Upon mating diploid cells sporulate readily, forming asci with 4 haploid spores. Their potential to secrete excessive quantities of heterologous proteins made them attention-grabbing for biotechnology, which expands as we speak additionally to different merchandise of major and secondary metabolism.

Deep Well Plate 96 Well 2.0 ML

AXYPDW20C PK50
EUR 196.8

96 well filter plate (960ul each well)

SD5006 12UNIT
EUR 115.85

96 Deep Well Plate Square Well V

PCR0246 PK50
EUR 322.8

Black 96 Well Plate, 1EA

X025-1EA 1EA
EUR 19

UNIFILTER PLATE 96 WELL 800 UL/WELL

WHA77002803 PK25
EUR 979.2

Adapter for 96 well plate

3510147 1unit
EUR 6697.2

Brand 96 Well Deep Well Plate-Stackable

BR701354-24EA PK24
EUR 163.2

Aligned Nanofibers 96 Well Plate

3D00012-96 700 nm-PCLs
EUR 132

96 well PCR plate ns

AXY2164 PK50
EUR 238.8

Streptavidin coated 96-well Plate

6523-5 each
EUR 392.4

96 Well ELISA Plate, 8-Well, Detachable, High Binding, WhiteFrame & Black Well,

504261 50 pcs/cs
EUR 26.29
Description: 96 Well ELISA Plate, 8-Well, Detachable, High Binding, WhiteFrame & Black Well, 5/pk, 50/cs

DEEP WELL PLATE 96 WELL 2.0 ML STERIL

AXYPDW20CS PK50
EUR 240

Plate 96 Well Immulon II

3455 PK50
EUR 283.2

96 Well Skirted PCR Plate

PCR1236 PK50
EUR 385.2

96 Well Semi Skirted Plate

PCR1216 PK50
EUR 204

1.2ML 96 WELL DEEP WELL PLATE HIGH CLARITY

P-DW-12-HC 5/pk
EUR 182.4
Description: Deep Well/Assay Plates - Axygen; Deep-well plates - Axygen

96 Deep Well Plate Round Wells

PCR0242 PK50
EUR 292.8

Nunc Lid for 96 well plate

264122 PK50
EUR 127.2

96 Deep Well Plate Square Wells

PCR0240 PK100
EUR 336

96 Deep Well Plate Square WellU

PCR0256 PK50
EUR 232.8

96 WELL PCR SEGMENTED PLATE

PCR-96-SG-C 10/pk
EUR 174
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

Tissue Culture Plate, 96 Well

TCP20-96 1 UNIT
EUR 64.18

96 Well ELISA Plate, 8-Well, Detachable, High Binding, White Frame & CLear Well,

504201 50 pcs/cs
EUR 38.5
Description: 96 Well ELISA Plate, 8-Well, Detachable, High Binding, White Frame & CLear Well, 5/pk, 50/cs

96 Well ELISA Plate, 8-Well, Detachable, High Binding, White Frame & White Well,

504271 50 pcs/cs
EUR 51.15
Description: 96 Well ELISA Plate, 8-Well, Detachable, High Binding, White Frame & White Well, 5/pk, 50/cs

Clear Coated 96 Well Plate, 1EA

C107-1EA 1EA
EUR 162

96 Well PCR Plate Clear Wells

PCR0972 PK50
EUR 258

96-Well Protein Folding Plate

PFS096 kit
EUR 347.84
Description: This product includes one 96-well plate with 96 protein folding solutions, 0.5 ml in each well of the mother plate; 1.4 ml of Inclusion Body Solubilizer; 4 ml of Neutralizer. Each experiment uses 0.1 ml of the solutions from the mother plate. Each mother plate contains 0.5 ml of solutions in each well and can be used for multiple experiments of folding various proteins.

Random Access 96 Well Plate Skir

PCR1412 PK50
EUR 301.2

Nori® Equine IgG ELISA Kit

GR106773 96-well
EUR 461

BioMag® 96-Well Plate Separator

8MB4109S-1 1magnet
EUR 955

Protein A-coated ELISA plate (8 well strips, 96 wells/plate) 5 plates/pack

PRTA55-5P 1 PK
EUR 315.6

Protein G-coated ELISA plate (8 well strips, 96 wells/plate) 5 plates/pack

PRTG65-5P 1 PK
EUR 315.6

Falcon Microtest Black 96 Well Plate

353376 PK32
EUR 217.2

96 Well ABI Fast Plate Pcr

PCR1200 PK50
EUR 258

Polystyrene-bottomed 96-well plate + lid (ELISPOT)

CT365 5
EUR 93.6

Plate 96 Well Immulon 1 FB

N3355 PK50
EUR 207.6

96 Deep Well Plate Round Wells U

PCR0228 PK100
EUR 217.2

96 Deep Well Plate Round Wells V

PCR0230 PK100
EUR 217.2

Nunc Lid for 96 Well Plate SH

263339 PK100
EUR 112.8

2 x Clear 96 well Plate, 2EA

X003-2EA 2EA
EUR 13

5 x Clear 96 well Plate, 5EA

X003-5EA 5EA
EUR 25

2 x Clear 96 well Plate, 2EA

X018-2EA 2EA
EUR 13

4 x Clear 96 Well Plate, 4EA

X018-4EA 4EA
EUR 31

PCR Plate Non Skirted 96 Well

MOL2364 PK50
EUR 309.6

96 Well Roche Style Pcr Plate

PCR1214 PK50
EUR 294

96 Well Roche Style PCR Plate

PCR1218 PK50
EUR 271.2

Benchmark Beadblaster 96 Adapter for 96 Well Plate

HOM3208 PK2
EUR 1710

Protein A&G-coated ELISA plate (8 well strips, 96 wells/plate) 5 plates/pack

PRTAG75-5P 1 PK
EUR 343.2

PCR Plate Semi Skirted 96 Well

MOL2366 PK50
EUR 301.2

96 Well Roche Style Qpcr Plate

PCR1210 PK50
EUR 283.2

96 well filter plate (no filter)

SD5006-EMPTY 12UNIT
EUR 104.89

96 Well Skirted Plate+ Q-Stick

PCR1238 PK50
EUR 277.2

Adaptor for 96-well PCR plate

APS-200-96PCR each
EUR 200

Black Half Area 96 Well Plate, 1EA

X023-1EA 1EA
EUR 25

96 Well Solid Bottom Plate Black

PCR0354 PK100
EUR 422.4

96 Well Solid Bottom Plate White

PCR0360 PK100
EUR 388.8

96 Well PCR Plate Divisible In12

PCR1064 PK50
EUR 174

96 Well Semi-Skirted PCR Plate

PCR1106 PK50
EUR 368.4

S100 96-well PCR Plate Adapter

E5391070026 EACH
EUR 379.2

S200 96-well PCR Plate Adapter

E5392070038 EACH
EUR 379.2

96 well DNA plate with membrane (960ul each well)

SD5007 12UNIT
EUR 291.24

96 well RNA plate with membrane (960ul each well)

SD5009 12UNIT
EUR 313.16

96-well plate Plasmid DNA Prep (mini)

TBS6012 2x 96-well Plates
EUR 442

Nori Equine IgM ELISA Kit (2 plates)

GR106524-2 2 x 96-well
EUR 832

Nori Equine IgE ELISA Kit (2 plates)

GR106525-2 2 x 96-well
EUR 832

Benchmark Beadblaster 96 Eva Cap Mat for 96 Well Deep Well Plate

HOM3232 EACH
EUR 121.2

96-Well Plate Viral DNA Miniprep Kit

VT92032 2XPlates, 192prep
EUR 495.86

96-Well Plate Plasmid DNA Miniprep Kit

BS415 5XPlates, 480prep
EUR 300.37

96-Well Plate Plasmid DNA Miniprep Kit

BS4152 2XPlates, 192prep
EUR 186.19

Nori Equine HGF ELISA Kit-2 Plates

GR106477-2 2 x 96-well
EUR 832

Nori Equine CRP ELISA Kit-2 Plates

GR106493-2 2 x 96-well
EUR 832

96-Well Plate DNA Cleanup Miniprep Kit

BS369 5XPlates, 480prep
EUR 300.37

96-Well Plate DNA Cleanup Miniprep Kit

BS3692 2xPlates, 192prep
EUR 186.19

Nori Equine VEGF ELISA Kit-2 Plates

GR106475-2 2 x 96-well
EUR 832

Nori Equine A1AT ELISA Kit-2 Plates

GR106490-2 2 x 96-well
EUR 832

Nori Equine A1PI ELISA Kit-2 Plates

GR106491-2 2 x 96-well
EUR 832

Nori Equine LDHA ELISA Kit-2 Plates

GR106492-2 2 x 96-well
EUR 832

Nori Equine eNOS ELISA Kit-2 Plates

GR106499-2 2 x 96-well
EUR 832

Nori Equine PCNA ELISA Kit-2 Plates

GR106500-2 2 x 96-well
EUR 832

Nori Equine HMGB1 ELISA Kit (2 plates)

GR106519-2 2 x 96-well
EUR 832

96 Well ELISA Plate, Undetachable, High Binding, Clear Frame & CLear Well, 5/pk,

514201 50 pcs/cs
EUR 30.36
Description: 96 Well ELISA Plate, Undetachable, High Binding, Clear Frame & CLear Well, 5/pk, 50/cs

PVDF membrane-bottomed 96-well plate + lid (ELISPOT)

CT366 5
EUR 268.8

96 WELL PLATE; SQUARE; U BASE; 1.6ML; PP; 96/PK

60180-P155 PK96
EUR 561.6

Nori® Equine HCG ELISA Kit- 2 Plates

GR106558-2 2 x 96-well
EUR 832

MULTIWELL PLATE POLYSTYRENE 96-WELL FLA

M2936-100EA PK100
EUR 131.87

PCR Plate 96 Well No Skirt Nat

LW2200 PK100
EUR 534

96-Well Plate PCR Products Purification Kit

BS365 5XPlates, 480prep
EUR 300.37

96-Well Plate PCR Products Purification Kit

BS3652 2xPlates, 192prep
EUR 186.19

96 WELL PLATE; SQUARE; 2ML; PP; 1/PK

60180-P403 EACH
EUR 19.2

Nori® Equine TLR9 ELISA Kit (2 plates)

GR106116-2 2 x 96-well
EUR 832

Nori® Equine TLR5 ELISA Kit (2 plates)

GR106119-2 2 x 96-well
EUR 832

Nori Equine IL-8 ELISA Kit-2 Plates

GR106476-2 2 x 96-well
EUR 832

Nori Equine IL-7 ELISA Kit-2 Plates

GR106482-2 2 x 96-well
EUR 832

Nori Equine SP-A ELISA Kit-2 Plates

GR106496-2 2 x 96-well
EUR 832

Nori Equine SP-D ELISA Kit-2 Plates

GR106497-2 2 x 96-well
EUR 832

Nori Equine KL-6 ELISA Kit-2 Plates

GR106498-2 2 x 96-well
EUR 832

Nori Equine MMP-3 ELISA Kit (2 plates)

GR106505-2 2 x 96-well
EUR 832

Nori Equine TIM-1 ELISA Kit (2 plates)

GR106515-2 2 x 96-well
EUR 832

Nori Equine TIM-2 ELISA Kit (2 plates)

GR106516-2 2 x 96-well
EUR 832

Nori Equine TIM-3 ELISA Kit (2 plates)

GR106517-2 2 x 96-well
EUR 832

Nori Equine TIM-4 ELISA Kit (2 plates)

GR106518-2 2 x 96-well
EUR 832

Nori® Equine PIGF ELISA Kit- 2 Plates

GR106561-2 2 x 96-well
EUR 832

Nori® Equine IFNa ELISA Kit- 2 Plates

GR106562-2 2 x 96-well
EUR 832

Nori® Equine GLP1 ELISA Kit- 2 Plates

GR106565-2 2 x 96-well
EUR 832

Nori® Equine UCP2 ELISA Kit- 2 Plates

GR106574-2 2 x 96-well
EUR 832

Nori® Equine PDGF ELISA Kit- 2 Plates

GR106576-2 2 x 96-well
EUR 832

Nori® Equine PTH ELISA Kit-2 Plates

GR106609-2 2 x 96-well
EUR 832

Nori® Equine TLR7 ELISA Kit (2 plates)

GR106087-2 2 x 96-well
EUR 832

96 WELL CLEAR PCR PLATE FOR ABI

PCR-96-AB-C 10/pk
EUR 200.4
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

1.2ML 96 WELL DEEP WELL PLATE HIGH CLARITY PRE-STERILIZED

P-DW-12-HC-S 5/pk
EUR 248.4
Description: Deep Well/Assay Plates - Axygen; Deep-well plates - Axygen

96 Well ExoELISA plate (12x8 well strips, pack of 10 plates)

EXOEL-96P-1 10 Plates
EUR 255.6

Equine Annexin V-Fluorescein Apoptosis Assay Kit

9141 500
EUR 455

Nori Equine MMP-2 ELISA Kit-2 Plates

GR106478-2 2 x 96-well
EUR 832

Nori Equine IL-32 ELISA Kit-2 Plates

GR106489-2 2 x 96-well
EUR 832

Nori Equine NF-kB ELISA Kit-2 Plates

GR106501-2 2 x 96-well
EUR 832

Nori® Equine IFNb1 ELISA Kit- 2 Plates

GR106563-2 2 x 96-well
EUR 832

Nori® Equine ACE2 ELISA Kit-2 Plates

GR106625-2 2 x 96-well
EUR 832

Nori® Equine iNOS ELISA Kit-2 Plates

GR106626-2 2 x 96-well
EUR 832

Nori® Equine PICP ELISA Kit-2 Plates

GR106630-2 2 x 96-well
EUR 832

Adapter for 96 well plate, pack of 2

IPD9600-96 each
EUR 1337.97

96 Well PCR Plate Divisible In 8

PCR1060 PK50
EUR 174

96 Well PCR Plate Divisible In 8

PCR1062 PK50
EUR 187.2

Targeted genome modifying is a sophisticated method that allows exact modification of the nucleic acid sequences in a genome. Genome modifying is usually carried out utilizing instruments, akin to molecular scissors, to chop an outlined location in a selected gene. Genome modifying has impacted numerous fields of biotechnology, akin to agriculture; biopharmaceutical manufacturing; research on the construction, regulation, and perform of the genome; and the creation of transgenic organisms and cell strains. Although genome modifying is used often, it has a number of limitations.

Here, we offer an outline of well-studied genome-editing nucleases, together with single-stranded oligodeoxynucleotides (ssODNs), transcription activator-like effector nucleases (TALENs), zinc-finger nucleases (ZFNs), and CRISPR-Cas9 RNA-guided nucleases (CRISPR-Cas9). To this finish, we describe the progress towards editable nuclease-based therapies and talk about the minimization of off-target mutagenesis. Future prospects of this difficult scientific area are additionally mentioned.  Komagataella yeasts normally develop as haploid cells and are secondary homothallic as they will change mating sort.

Green recycling process for polyurethane foams by a chem-biotech approach

Green recycling process for polyurethane foams by a chem-biotech approach

Polyurethanes are extremely resistant supplies used for constructing insulation or automotive seats. The polyurethane end-of-life situation should be addressed by the event of environment friendly recycling strategies. Since typical recycling processes usually are not appropriate for thermosets, waste administration of PU foam is especially questioning. By coupling organic and chemical processes, this research goals at creating a inexperienced recycling pathway for PU foam utilizing enzymes for depolymerization. For occasion, enzymatic degradation of a PU foam synthesized with polycaprolactone and toluene diisocyanate led to a weight lack of 25 % after 24 h of incubation.

The corresponding degradation merchandise have been recovered and recognized as 6-hydroxycaproic acid and a quick acid-terminated diurethane. An organo-metallic catalyzed synthesis of second technology polymers from these constructing blocks was carried out. A polymer with a excessive common molar mass of 74 000 (Mw) was obtained by mixing 50 % of recycled constructing blocks and 50 % of neat 6-hydroxycaproic acid. A poly(ester urethane) have been synthesized with out using poisonous and decrier polyisocyanates. It is the primary time that a research presents the imaginative and prescient of a recycling loop ranging from PU wastes and ending with a second technology polymer in a full round approach

mRNA applied sciences have the potential to remodel areas of medication, together with the prophylaxis of infectious ailments. The benefits for vaccines vary from the acceleration of immunogen discovery to speedy response and a number of illness goal manufacturing. A higher understanding of high quality attributes that dictate translation effectivity, in addition to a complete appreciation of the significance of mRNA supply, are influencing a new period of funding in growth actions. The utility of translational sciences and rising early-phase scientific expertise proceed to tell candidate vaccine choice. Here we evaluation the state-of-the-art for the prevention of infectious ailments by utilizing mRNA and pertinent matters to the biotechnology and pharmaceutical industries.

Quadrivalent Influenza Vaccine (Sinovac Biotech) for seasonal influenza prophylaxis

Quadrivalent Influenza Vaccine (Sinovac Biotech) is a quadrivalent split-virion inactivated influenza vaccine authorized in China in June 2020 for people ≥three years of age. It comprises 15 µg hemagglutinin per pressure together with A/H1N1, A/H3N2, B/Victoria, and B/Yamagata, which might probably enhance safety in opposition to influenza B viruses. In this evaluation, we summarize the event of quadrivalent influenza vaccines in China and overseas nations, and assess the immunogenicity and security from the section I and III scientific trials of Quadrivalent Influenza Vaccine in people ≥three years of age. We additionally talk about the potential utility of Quadrivalent Influenza Vaccine in younger kids 6-35 months of age based on the outcomes of the section III trial.
The immunogenicity and security profiles of Quadrivalent Influenza Vaccine containing two A and two B strains have been corresponding to the trivalent vaccines for the shared strains. The addition of a second B pressure to the trivalent vaccine might induce superior immune responses for the alternate B pressure. Since the 2 B strains co-circulated worldwide, the introduction of quadrivalent influenza vaccines has been anticipated to be a cost-effective technique. We in contrast the monetary efficiency of 319 BIOTECH corporations targeted on creating therapeutics with IPOs from 1997-2016, to that of paired, non-biotech CONTROL corporations with concurrent IPO dates. Both cohorts exhibited a high-risk/excessive reward sample of return, with the bulk shedding worth, however many reaching progress multiples. 
BIOTECH corporations had a distinctly totally different monetary construction with excessive R&D expense, little income, and unfavorable income (losses), however a comparable length of itemizing on public markets and frequency of acquisitions. Through 2016, BIOTECH and CONTROL corporations had equal progress in market cap and shareholder worth (>$100 billion), however BIOTECH corporations had decrease internet worth creation ($93 billion vs $411 billion). While investments in biotechnology are sometimes thought-about to be distinctively dangerous, we conclude that worth creation by biotech corporations after IPO resembles that of non-biotech corporations at a comparable stage and doesn’t current a disproportionate funding threat.
Green recycling process for polyurethane foams by a chem-biotech approach

Swiss Startup Framework: A Highly Effective Network Supporting the Generation of Emerging Biotech Businesses

For over 50 years, Switzerland has been one of many main nations driving innovation in biotechnology and its industrial purposes. Today, some 1,000 biotech corporations kind a tightly knit, cross-functional community starting from analysis by means of to manufacturing. This community contains R&D corporations, contract analysis organizations, and extremely specialised advisors and biotech traders. Together, they kind an exterior innovation pool that enhances the in-house R&D capability of the massive multi-national pharma corporations. A extremelyefficient startup framework, strong acceleration mechanisms, and progressive traders allow the emergence of a steady stream of biotech startups that revitalize the trade with new applied sciences and merchandise supporting drug growth and diagnostics.

NanoMolar Phosphate Assay Kit

NPA1000 1000 assays
EUR 168.93
Description: This product includes 100 ml of Reagent P1 and 1 ml of 100 x Reagent P2 and 0.1 ml of 1 mM potassium phosphate (KH2PO4). It is for 1000 assays using 96-well plates (100 ul of sample volume) or 4000 assays using 384-well plates (25 l of sample volume). The following protocol is for assays using 96-well plates. Cuvettes may also be used for the measurement.

Phosphate Assay Kit (Fluorometric)

K2076-100 100 assays
EUR 435.6

Phosphate Assay Kit (Fluorometric)

K420-100 each
EUR 418.8

Phosphate Assay Kit (Fluorometric)

STA-686 1000 assays
EUR 582
Description: Our Phosphate Assay Kit (Fluorometric) measures total inorganic phosphate present in lysates, solutions, food, or biological samples in a 96-well fluorescence-based plate reader. 1000 assays/kit.

PiBlue™ Phosphate Assay Kit

POPB-500 500
EUR 239
Description: For sensitive and high-throughput phosphate determination. Key Features: Reagent very stable. Due to our innovative formulation, no precipitation of reagent occurs. Therefore no filtration of reagent is needed prior to assays, as is often required with other commercial kits. High sensitivity and wide detection range: detection of as little of 20 pmoles of phosphate and useful range between 0.4 µM and 50 µM phosphate. Fast and convenient: single reagent "mix-and-measure" assay allows quantitation of free phosphate within 30 minutes. Compatible with routine laboratory and HTS formats: assays can be performed in tubes, cuvettes or microplates, on spectrophotometers and plate readers. Robust and amenable to HTS: Z factors of 0.7 to 0.9 are observed in 96-well plates. Can be readily automated on HTS liquid handling systems Method: OD620nm (malachite green). Samples: Enzyme reactions with free phosphate releases. Species: All. Procedure: Assay takes 30 min. Kit size: 500 tests. Detection limit: 0.4 µM.

QuantiChrom™ Phosphate Assay Kit

DIPI-500 500
EUR 349
Description: For quantitative determination of phosphate and evaluation of drug effects on phosphate metabolism. Key Features: Sensitive and accurate. Linear detection range 0.3 µM (0.0028 mg/dL) to 50 µM (0.47 mg/dL) phosphate in 96-well plate assay. Simple and high-throughput. The procedure involves addition of a single working reagent and incubation for 30 min. Can be readily automated as a high-throughput assay for thousands of samples per day. Improved reagent stability and versatility. The optimized formulation has greatly enhanced reagent and signal stability. Assays can be executed in cuvet or 96-well plate. Low interference in biological samples. No pretreatments are needed. Assays can be directly performed on raw biological samples i.e., in the presence of lipid, protein and minerals. Method: OD620nm (malachite green). Samples: Serum, urine, saliva, sweat, tissue culture, food, environment etc. Species: All. Procedure: Assay takes 30 min. Kit size: 500 tests. Detection limit: 3 µg/dL (0.3 µM).

Malachite Green Phosphate Assay kit

65-POMG-25H 2500 tests
EUR 333

Malachite Green Phosphate Assay Kit

abx298878-100Assays 100 Assays
EUR 453.6

Malachite Green Phosphate Assay Kit

POMG-25H 2500
EUR 259
Description: For sensitive and high-throughput phosphate determination. Key Features: Reagent very stable. Due to our innovative formulation, no precipitation of reagent occurs. Therefore no filtration of reagent is needed prior to assays, as is often required with other commercial kits. High sensitivity and wide detection range: detection of as little of 1.6 pmoles of phosphate and useful range between 0.02 µM and 40 µM phosphate. Fast and convenient: homogeneous "mix-and-measure" assay allows quantitation of free phosphate within 20 minutes. Compatible with routine laboratory and HTS formats: assays can be performed in tubes, cuvettes or microplates, on spectrophotometers and plate readers. Robust and amenable to HTS: Z factors of 0.7 to 0.9 are observed in 96-well and 384-well plates. Can be readily automated on HTS liquid handling systems. Method: OD620nm (malachite green). Samples: Biological, environment etc. Species: All. Procedure: Assay takes 30 min. Kit size: 2500 tests. Detection limit: 0.02 µM.

Malachite Green Phosphate Assay Kit

Z5030012 2,500 assays
EUR 312

Phosphate Fluorometric Assay Kit

55R-1404 100 assays
EUR 525.6
Description: Assay Kit for detection of Phosphate in the research laboratory

Phosphate Colorimetric Assay Kit

k2074-500 500 assays
EUR 351.6

Phosphate Colorimetric Assay Kit

K410-500 each
EUR 379.2

Sucrose Phosphate Synthase Assay Kit

abx298805-100Assays 100 Assays
EUR 754.8

Phosphoprotein Phosphate Estimation Assay Kit

BSP061 2000Assays, 2000preps
EUR 110.11

PicoProbe? Phosphate Fluorometric Assay Kit

K419-100 each
EUR 535.2

MESG *Phosphate assay reagent*

21600-1MG 1 mg
EUR 77

MESG *Phosphate assay reagent*

21600-1MG-1mg 1 mg
EUR 77
Description: In the presence of inorganic phosphate MESG is converted to 2-amino-6-mercapto-7-methlpurine by purine nucleoside phosphorylase (EC 2.4.2.1) with absorption wavelength shift to red.

MESG *Phosphate assay reagent*

21600-5mg 5 mg
EUR 199
Description: In the presence of inorganic phosphate MESG is converted to 2-amino-6-mercapto-7-methlpurine by purine nucleoside phosphorylase (EC 2.4.2.1) with absorption wavelength shift to red.

PhosphoWorksâ„¢ Colorimetric Phosphate Assay Kit *Blue Color*

21665-1000Tests 1000 Tests
EUR 222
Description: Phosphate is involved in many biological reactions.

MicroMolar Phosphate Assay Reagent

MPA3000 3000 assays
EUR 168.93
Description: This product includes 450 ml of reagent. It is for 3000 to 5000 assays using 96-well plates or more than 10,000 assays using 384-well plates. It can also be used for measurement of phosphate concentrations using cuvettes and a spectrophotometer.

PhosphoWorksâ„¢ Fluorimetric Phosphate Assay Kit *Red Fluorescence*

21660-125Tests 125 Tests
EUR 334
Description: Cells utilize a wide variety of phosphate (Pi) and polyphosphate esters as enzyme substrates, second messengers, membrane structural components and vital energy reservoirs.

PhosphoWorksâ„¢ Fluorimetric Phosphate Assay Kit *Red Fluorescence*

21661-1250Tests 1250 Tests
EUR 2197
Description: Cells utilize a wide variety of phosphate (Pi) and polyphosphate esters as enzyme substrates, second messengers, membrane structural components and vital energy reservoirs.

Malachite Green Phosphate Microplate Assay Kit

DLSM0112 100 Assays
EUR 262.5
Description: Detection and Quantification of Phosphate Content.

Sucrose Phosphate Synthase Microplate Assay Kit

DLSM0039 100 Assays
EUR 595
Description: Detection and Quantification of Sucrose Phosphate Synthase Activity.

Phosphate Assay, Catalog: MA-0105

MA-0105 100 wells
EUR 255

PhosphoWorksâ„¢ Colorimetric MESG Phosphate Assay Kit *UV absorption*

21659-200Tests 200 Tests
EUR 334
Description: In the presence of inorganic phosphate MESG is converted to 2-amino-6-mercapto-7-methlpurine by purine nucleoside phosphorylase (EC 2.4.2.1) with absorption wavelength shift to red.

Mannose Phosphate Isomerase (MPI) Magnetic Luminex Assay Kit

LKU600969-96T 96T
EUR 966

PicoProbe? Dihydroxyacetone Phosphate (DHAP) Fluorometric Assay Kit

K673-100 each
EUR 927.6

Triose Phosphate Isomerase (TPI) Activity Colorimetric Assay Kit

K670-100 each
EUR 783.6

Amplite® Fluorimetric Glycerol 3-Phosphate (G3P) Assay Kit

13837-200Tests 200 Tests
EUR 390
Description: Glycerol 3-Phosphate (G3P) is an important intermediate in the glycolysis metabolic pathway.

Amplite® Colorimetric Glycerol 3-Phosphate (G3P) Assay Kit

13838-200Tests 200 Tests
EUR 390
Description: Glycerol 3-Phosphate (G3P) is an important intermediate in glycolysis metabolic pathway.

Glucose 6 Phosphate Isomerase (GPI) Magnetic Luminex Assay Kit

LKU605314-96T 96T
EUR 869.4

Glucose 6 Phosphate Isomerase (GPI) Magnetic Luminex Assay Kit

LKU605315-96T 96T
EUR 894.7

Glucose 6 Phosphate Isomerase (GPI) Magnetic Luminex Assay Kit

LKU605316-96T 96T
EUR 944.2

Sphingosine 1 Phosphate Lyase 1 (SGPL1) Magnetic Luminex Assay Kit

LKU601150-96T 96T
EUR 993.6

Sphingosine 1 Phosphate Receptor 1 (S1PR1) Magnetic Luminex Assay Kit

LKU601152-96T 96T
EUR 993.6

Sphingosine 1 Phosphate Receptor 1 (S1PR1) Magnetic Luminex Assay Kit

LKU601154-96T 96T
EUR 966

Sphingosine 1 Phosphate Receptor 2 (S1PR2) Magnetic Luminex Assay Kit

LKU601155-96T 96T
EUR 993.6

Sphingosine 1 Phosphate Receptor 3 (S1PR3) Magnetic Luminex Assay Kit

LKU601160-96T 96T
EUR 993.6

Sphingosine 1 Phosphate Receptor 3 (S1PR3) Magnetic Luminex Assay Kit

LKU601162-96T 96T
EUR 966

Sphingosine 1 Phosphate Receptor 3 (S1PR3) Magnetic Luminex Assay Kit

LKU601165-96T 96T
EUR 1048.8

Sphingosine 1 Phosphate Receptor 4 (S1PR4) Magnetic Luminex Assay Kit

LKU601167-96T 96T
EUR 993.6

Sphingosine 1 Phosphate Receptor 5 (S1PR5) Magnetic Luminex Assay Kit

LKU601170-96T 96T
EUR 993.6

PPDK (Pyruvate, phosphate dikinase) Activity Assay Kit (Fluorometric/Colorimetric)

K456-100 each
EUR 574.8

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Magnetic Luminex Assay Kit

LKU606125-96T 96T
EUR 1125.9

Carbamoyl Phosphate Synthase 1, Mitochondrial (CPS1) Magnetic Luminex Assay Kit

LKU603105-96T 96T
EUR 966

Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) Magnetic Luminex Assay Kit

LKU604878-96T 96T
EUR 944.2

Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) Magnetic Luminex Assay Kit

LKU604880-96T 96T
EUR 869.4

Dolichyl Phosphate-N-Acetylglucosaminephosphotransferase 1 (DPAGT1) Magnetic Luminex Assay Kit

LKU605289-96T 96T
EUR 966

Phosphatidylcholine Assay Kit

55R-1443 100 assays
EUR 807.6
Description: Assay Kit for detection of Phosphatidylcholine in the research laboratory

Phosphatidylcholine Assay Kit

STA-600 96 assays
EUR 622.8
Description: Cell Biolabs? Phosphatidylcholine Assay Kit measures the phosphatidylcholine present within serum, plasma, or tissue samples.Samples are compared to a known concentration of phosphatidylcholine standard within the 96-well microtiter plate format.  Samples and standards are incubated for 60 minutes and then read with a standard 96-well fluorometric plate reader.

Acid Phosphatase Assay Kit

abx096000-100Assays 100 Assays
EUR 416.4

pNPP Phosphatase Assay Kit

POPN-01K 1000
EUR 408
Description: Quantitative determination of phosphatase activity by colorimetric (405nm) method. Kit size: 1000 tests. Shelf life: 12 months. Shipping: ambient temp; storage: 4, -20°C.

pNPP Phosphatase Assay Kit

POPN-500 500
EUR 249
Description: For quantitative determination of phosphatase enzyme activity. Key Features: High sensitivity and wide linear range. The detection limit is generally 3 ng phosphatase or below. Homogeneous and simple procedure. No wash or reagent transfer steps are involved. The assay can be completed within 30 minutes. Robust and amenable to HTS. All reagents are compatible with high-throughput liquid handling instruments. Method: OD405nm. Samples: Protein phosphatases. Species: All. Procedure: Assay takes 30 min. Kit size: 500 tests. Detection limit: 3 ng.

pNPP Phosphatase Assay Kit

Z5030009 500 assays
EUR 213

pNPP Phosphatase Assay Kit

Z5030010 1,000 assays
EUR 213

Sphingosine-1-Phosphate Phosphatase 1 (SGPP1) Magnetic Luminex Assay Kit

LKU601142-96T 96T
EUR 1048.8

Sphingosine-1-Phosphate Phosphatase 1 (SGPP1) Magnetic Luminex Assay Kit

LKU601144-96T 96T
EUR 966

Sphingosine-1-Phosphate Phosphatase 2 (SGPP2) Magnetic Luminex Assay Kit

LKU601147-96T 96T
EUR 1048.8

Alkaline Phosphatase Assay Kit

abx098406-Hitachi7060R190ml2R245ml1 Hitachi 7060; R1: 90ml×2 R2: 45ml×1
EUR 266.4

Alkaline Phosphatase Assay Kit

abx098406-Hitachi7170R132ml4R28ml4 Hitachi 7170; R1: 32ml×4 R2: 8ml×4
EUR 266.4

Alkaline Phosphatase Assay Kit

abx098406-Toshiba120R150ml4R250ml1 Toshiba 120; R1: 50ml×4 R2: 50ml×1
EUR 266.4

Alkaline Phosphatase Assay Kit

abx098406-Toshiba40R150ml4R250ml1 Toshiba 40; R1: 50ml×4 R2: 50ml×1
EUR 266.4

Alkaline Phosphatase Assay Kit

abx096002-100Assays 100 Assays
EUR 379.2

Alkaline Phosphatase Assay Kit

Z5030033 250 assays
EUR 651

Acid Phosphatase Activity Assay Kit

55R-1405 500 assays
EUR 525.6
Description: Assay Kit for detection of Acid Phosphatase in the research laboratory

Acid Phosphatase Activity Assay Kit

55R-1866 500 assays
EUR 580.8
Description: Assay Kit for detection of Acid Phosphatase in the research laboratory

MicroGram Phosphatidylcholine Assay Kit

MPC200K 200 assays
EUR 234.99
Description: This product includes MPC reagent A, MPC reagent B, 100 x MPC reagent C, MPC reagent D, and a standard solution of L-α-phosphatidylcholine (1 mg/ml). The assay kit sufficient for measurement of 200 samples of L-α-phosphatidylcholine using 96-well plates (Costar 3915 and Greiner 655076).

Acid Phosphatase Microplate Assay Kit

DLSM0001 100 Assays
EUR 210
Description: Detection and Quantification of Acid Phosphatase Activity.

Total Phosphatase Microplate Assay Kit

DLSM0176 100 Assays
EUR 140
Description: Detection and Quantification of Total Phosphatase Activity.

Phosphatidylserine Assay Kit (Fluorometric)

K565-100 each
EUR 744

Phosphatidylglycerol/Cardiolipin Assay Kit

MET-5024 100 assays
EUR 602.4
Description: Our Phosphatidylglycerol/Cardiolipin Assay Kit measures both phosphatidylglycerol and cardiolipin in cell lysate samples by a coupled enzymatic reaction system. First, lipase is used to hydrolyze phosphatidylglycerol and cardiolipin to glycerol, which is then phosphorlyated by glycerol kinase to yield glycerol-3-phosphate. Next, the glycerol-3-phosphate product is oxidized by glycerol-3-phosphate oxidase (GPO), producing hydrogen peroxide. The hydrogen peroxide released from this reaction reacts specifically with the kit?s Fluorometric Probe and is detected at ex. 530-560 nm/em. 585-595 nm. Phosphatidylglycerol and cardiolipin levels in unknown sampled are determined based on the provided cardiolipin standard curve.

Alkaline Phosphatase Activity Assay Kit

55R-1402 500 assays
EUR 888
Description: Assay Kit for detection of Alkaline Phosphatase in the research laboratory

Alkaline Phosphatase Activity Assay Kit

55R-1406 500 assays
EUR 525.6
Description: Assay Kit for detection of Alkaline Phosphatase in the research laboratory

Phosphatidylglycerol Assay Kit (Fluorometric)

K488-100 each
EUR 679.2

Neutral Phosphatase Microplate Assay Kit

DLSM0207 100 Assays
EUR 210
Description: Detection and Quantification of Acid Phosphatase Activity.

Alkaline Phosphatase Microplate Assay Kit

DLSM0003 100 Assays
EUR 175
Description: Detection and Quantification of Alkaline Phosphatase Activity.

QuantiFluo™ Acid Phosphatase Assay Kit

FACP-100 100
EUR 159
Description: For quantitative determination of acid phosphatase activity in biological samples. Key Features: Fast and sensitive. Linear detection range (20 µL sample): 0.008 to 10 U/L for a 30 minute reaction. High-throughput. Homogeneous "mix-incubate-measure" type assay. Can be readily automated on HTS liquid handling systems for processing thousands of samples per day. Method: FL360/450. Samples: Biological (e.g. serum) samples. Species: All. Procedure: Assay takes 30 min. Kit size: 100 tests. Detection limit: 0.008 U/L.

QuantiChrom™ Acid Phosphatase Assay Kit

DACP-100 100
EUR 169
Description: For quantitative determination of acid phosphatase activity in biological samples. Key Features: Fast and sensitive. Linear detection range (20 µL sample): 0.05 to 60 U/L for a 30 minute reaction. High-throughput. Homogeneous "mix-incubate-measure" type assay. Can be readily automated on HTS liquid handling systems for processing thousands of samples per day. Method: OD405nm. Samples: Biological (e.g. serum) samples. Species: All. Procedure: Assay takes 30 min. Kit size: 100 tests. Detection limit: 0.05 U/L.

Phosphatidylethanolamine Assay Kit (Fluorometric)

K499-100 each
EUR 757.2

Acid Phosphatase Cell Cytotoxicity Assay Kit

K937-500 each
EUR 444

QuantiFluo™ Alkaline Phosphatase Assay Kit

QFAP-100 100
EUR 229
Description: For quantitative determination of alkaline phosphatase (ALP) activity using stable 4-methylumbelliferyl phosphate substrate. Key Features: High sensitivity and wide linear range. Use 10 µL sample. Detection limit of 0.02 U/L (20 min reaction). Homogeneous and simple procedure. Simple "mix-and-measure" procedure allows reliable quantitation of ALP activity within 20 minutes. Robust and amenable to HTS. All reagents are compatible with high-throughput liquid handling instruments. Method: FL360/450nm. Samples: Serum, plasma etc. Species: All. Procedure: Assay takes 20 min. Kit size: 100 tests. Detection limit: 0.02 U/L.

QuantiChrom™ Alkaline Phosphatase Assay Kit

DALP-250 250
EUR 369
Description: For quantitative determination of alkaline phosphatase (ALP) activity using stable p-nitrophenol phosphate substrate. Key Features: High sensitivity and wide linear range. Use 5 µL serum or plasma sample. The detection limit is 2 U/L, linear up to 800 U/L. Homogeneous and simple procedure. Simple "mix-and-measure" procedure allows reliable quantitation of ALP activity within 5 minutes. Robust and amenable to HTS. All reagents are compatible with high-throughput liquid handling instruments. Method: OD405nm. Samples: Serum, plasma etc. Species: All. Procedure: Assay takes 4 min. Kit size: 250 tests. Detection limit: 2 U/L.

Total Phosphatidic Acid Assay Kit (Fluorometric)

MET-5019 100 assays
EUR 602.4
Description: Our Total Phosphatidic Acid Assay Kit measures total phosphatidic acid content (PA and LPA) in cell lysate samples by a coupled enzymatic reaction system. First, lipase is used to hydrolyze phosphatidic acid to glycerol-3-phosphate. Next, the glycerol-3-phosphate product is oxidized by glycerol-3-phosphate oxidase (GPO), producing hydrogen peroxide. The hydrogen peroxide released from this reaction reacts specifically with the kit?s Fluorometric Probe and is detected at ex. 530-560 nm/em. 585-595 nm. Phosphatidic Acid levels in unknown sampled are determined based on the provided phosphatidic acid standard curve.

Acid Phosphatase Activity Colorimetric Assay Kit

K411-500 each
EUR 430.8

Acid Phosphatase Activity Fluorometric Assay Kit

K421-500 each
EUR 418.8

Phosphatidylserine (PS) Magnetic Luminex Assay Kit

LKU607510-96T 96T
EUR 1115.5

Phosphatidylinositol (PI) Magnetic Luminex Assay Kit

LKU607445-96T 96T
EUR 1117.8

PicoProbeTM Phosphatidylinositol Assay Kit (Fluorometric)

K750-100 each
EUR 718.8

Phosphatidylcholine Colorimetric/Fluorometric Assay Kit

K576-100 each
EUR 588

Phosphatidylcholine Colorimetric/Fluorometric Assay Kit

K2086-100 100 assays
EUR 602.4

PicoProbeTM Phosphatidic Acid Assay Kit (Fluorometric)

K748-100 each
EUR 744

Alkaline Phosphatase Activity Colorimetric Assay Kit

K2075-500 500 assays
EUR 652.8

Alkaline Phosphatase Activity Fluorometric Assay Kit

K2077-500 500 assays
EUR 435.6

Alkaline Phosphatase Activity Colorimetric Assay Kit

K412-500 each
EUR 646.8

Alkaline Phosphatase Activity Fluorometric Assay Kit

K422-500 each
EUR 418.8

Alkaline Phosphatase (ALP) Magnetic Luminex Assay Kit

LKU600094-96T 96T
EUR 966

Alkaline Phosphatase (ALP) Magnetic Luminex Assay Kit

LKU607078-96T 96T
EUR 917.7

Alkaline Phosphatase (ALP) Magnetic Luminex Assay Kit

LKU607079-96T 96T
EUR 995.9

Alkaline Phosphatase (ALP) Magnetic Luminex Assay Kit

LKU607080-96T 96T
EUR 944.2

Alkaline Phosphatase (ALP) Magnetic Luminex Assay Kit

LKU607081-96T 96T
EUR 995.9

Prostatic Acid Phosphatase (PAP) Magnetic Luminex Assay Kit

LKU600999-96T 96T
EUR 869.4

StemTAG Alkaline Phosphatase Activity Assay Kit, Colorimetric

CBA-301 100 assays
EUR 483.6
Description: Alkaline Phosphatase (AP) is a widely used marker for both mouse and human embryonic stem cells (ES) and embryonic germ cells (EG). Our StemTAG Alkaline Phosphatase kits provide an efficient system for monitoring cell differentiation or undifferentiation using the AP marker. The StemTAG Alkaline Phosphatase Activity Assay Kits provide reagents for quantifying alkaline phosphatase activity in a convenient 96-well plate format, with either colorimetric or fluorescence detection.

StemTAG Alkaline Phosphatase Activity Assay Kit, Fluorometric

CBA-307 100 assays
EUR 540
Description: Alkaline Phosphatase (AP) is a widely used marker for both mouse and human embryonic stem cells (ES) and embryonic germ cells (EG). Our StemTAG Alkaline Phosphatase kits provide an efficient system for monitoring cell differentiation or undifferentiation using the AP marker. The StemTAG Alkaline Phosphatase Activity Assay Kits provide reagents for quantifying alkaline phosphatase activity in a convenient 96-well plate format, with either colorimetric or fluorescence detection.

Protein Tyrosine Phosphatase Activity Assay Kit (Fluorometric)

K829-100 each
EUR 639.6

Neutrophil Alkaline Phosphatase (NAP) Magnetic Luminex Assay Kit

LKU603747-96T 96T
EUR 917.7

Alkaline Phosphatase, Placental (ALPP) Magnetic Luminex Assay Kit

LKU600650-96T 96T
EUR 917.7

Phosphatidylinositol Glycan L (PIGL) Magnetic Luminex Assay Kit

LKU607485-96T 96T
EUR 966

Acid Phosphatase 2, Lysosomal (ACP2) Magnetic Luminex Assay Kit

LKU604364-96T 96T
EUR 966

Acid Phosphatase 2, Lysosomal (ACP2) Magnetic Luminex Assay Kit

LKU600071-96T 96T
EUR 993.6

Phosphatidylserine Decarboxylase (PISD) Magnetic Luminex Assay Kit

LKU607512-96T 96T
EUR 966

Genorise® Alkaline Phosphatase Activity Colorimetric Assay Kit

GR107015 100 tests
EUR 289

Genorise® Alkaline Phosphatase Activity Fluorometric Assay Kit

GR107016 100 tests
EUR 289

Alkaline Phosphatase, Intestinal (ALPI) Magnetic Luminex Assay Kit

LKU600891-96T 96T
EUR 917.7

Alkaline Phosphatase, Intestinal (ALPI) Magnetic Luminex Assay Kit

LKU600894-96T 96T
EUR 995.9

Phosphatase And Tensin Homolog (PTEN) Magnetic Luminex Assay Kit

LKU607394-96T 96T
EUR 772.8

Phosphatase And Tensin Homolog (PTEN) Magnetic Luminex Assay Kit

LKU607397-96T 96T
EUR 794.7

Phosphatase And Tensin Homolog (PTEN) Magnetic Luminex Assay Kit

LKU607400-96T 96T
EUR 839.5

Phosphatidylinositol Trisphosphate (PIP3) Magnetic Luminex Assay Kit

LKU607508-96T 96T
EUR 1269.6

Density Enhanced Phosphatase 1 (DEP1) Magnetic Luminex Assay Kit

LKU607441-96T 96T
EUR 917.7

Pyruvate Dehydrogenase Phosphatase (PDP) Magnetic Luminex Assay Kit

LKU606421-96T 96T
EUR 869.4

Dual Specificity Phosphatase 1 (DUSP1) Magnetic Luminex Assay Kit

LKU601972-96T 96T
EUR 966

Dual Specificity Phosphatase 1 (DUSP1) Magnetic Luminex Assay Kit

LKU601985-96T 96T
EUR 993.6

Dual Specificity Phosphatase 5 (DUSP5) Magnetic Luminex Assay Kit

LKU601993-96T 96T
EUR 993.6

Dual Specificity Phosphatase 5 (DUSP5) Magnetic Luminex Assay Kit

LKU602001-96T 96T
EUR 966

Dual Specificity Phosphatase 6 (DUSP6) Magnetic Luminex Assay Kit

LKU602006-96T 96T
EUR 966

Dual Specificity Phosphatase 9 (DUSP9) Magnetic Luminex Assay Kit

LKU602016-96T 96T
EUR 966

Amplite® Luminometric Alkaline Phosphatase Assay Kit *Luminescence*

11956 100 Tests
EUR 222

Amplite® Luminometric Alkaline Phosphatase Assay Kit *Luminescence*

11956-100Tests 100 Tests
EUR 222
Description: Alkaline phosphatase is a highly sensitive enzyme for ELISA, immuno-histochemical, Northern, Southern and Western blot applications.

Amplite® Colorimetric Alkaline Phosphatase Assay Kit *Yellow Color*

11950-500Tests 500 Tests
EUR 166
Description: Alkaline phosphatase is a highly sensitive enzyme for ELISA, immuno-histochemical, Northern, Southern and Western blot applications.

Acid Phosphatase 5, Tartrate Resistant (ACP5) Magnetic Luminex Assay Kit

LKU600061-96T 96T
EUR 894.7

The age of immuno-oncology has ushered in a rush inside the biopharmaceutical trade. This intense focus has been characterised as a frenzy or overhyped, however represents a substantial funding in new merchandise that hope to harness the immune system in opposition to most cancers. Such brokers embrace next-generation checkpoint antagonists, immune costimulatory agonists, and a numerous array of novel mechanisms of motion and therapeutic modalities concentrating on immune cell varieties and the interaction of the host and tumor on the immune synapse. This article surveys the scientific growth and funding exercise with Immuno-Oncology, particularly prostate, kidney, and bladder cancers.

Bigger and Better? Representativeness of the Influenza A Surveillance Using One Consolidated Clinical Microbiology Laboratory Data Set as Compared to the Belgian Sentinel Network of Laboratories.

Bigger and Better? Representativeness of the Influenza A Surveillance Using One Consolidated Clinical Microbiology Laboratory Data Set as Compared to the Belgian Sentinel Network of Laboratories.

Infectious illnesses stay a severe public well being concern globally, whereas the want for dependable and consultant surveillance techniques stays as acute as ever.

The public well being surveillance of infectious illnesses makes use of reported optimistic outcomes from sentinel medical laboratories or laboratory networks, to survey the presence of particular microbial brokers recognized to represent a risk to public well being in a given inhabitants.

This monitoring exercise is usually based mostly on a consultant fraction of the microbiology laboratories nationally reporting to a single central reference level.

However, in recent times a quantity of medical microbiology laboratories (CML) have undergone a course of of consolidation involving a shift towards laboratory amalgamation and nearer real-time informational linkage.

This report goals to examine whether or not such merging actions might need a possible affect on infectious illnesses surveillance. Influenza knowledge was used from Belgian public well being surveillance 2014-2017, to consider whether or not nationwide an infection traits might be estimated equally as successfully from solely only one centralized CML serving the wider Brussels space (LHUB-ULB).

The total comparability reveals that there’s a shut correlation and representativeness of the LHUB-ULB knowledge to the nationwide and worldwide knowledge for the similar time durations, each on epidemiological and molecular grounds.

Notably, the effectiveness of the LHUB-ULB surveillance stays partially topic to native regional variations. A subset of the Influenza samples had their entire genome sequenced in order that the noticed epidemiological traits might be correlated to molecular observations from the similar interval, as an added-value proposition.

These outcomes illustrate that the real-time integration of high-throughput entire genome sequencing platforms accessible in consolidated CMLs into the public well being surveillance system just isn’t solely credible but in addition advantageous to use for future surveillance and prediction functions.

This might be best when carried out for automated detection techniques which may embody a number of layers of data and well timed implementation of management methods.

Bigger and Better? Representativeness of the Influenza A Surveillance Using One Consolidated Clinical Microbiology Laboratory Data Set as Compared to the Belgian Sentinel Network of Laboratories.
Bigger and Better? Representativeness of the Influenza A Surveillance Using One Consolidated Clinical Microbiology Laboratory Data Set as Compared to the Belgian Sentinel Network of Laboratories.

Establishing a world laboratory community for uncared for tropical illnesses: Understanding current capability in 5 WHO areas.

Background. Limited laboratory capability is a big bottleneck in assembly international targets for the management and elimination of uncared for tropical illnesses (NTD).

Laboratories are important for offering medical knowledge and monitoring knowledge about the standing and adjustments in NTD prevalence, and for detecting early drug resistance.

Currently NTD laboratory networks are casual and specialist laboratory experience just isn’t nicely publicised, making it troublesome to share international experience and present coaching, supervision, and high quality assurance for NTD prognosis and analysis.

This research aimed to establish laboratories inside 5 World Health Organisation areas (South-East Asia, Eastern Mediterranean, Americas, Western Pacific and Europe) that present NTD providers and might be regarded as nationwide or regional reference laboratories, and to conduct a survey to doc their networks and capability to help NTD programmes. Methods. 

Potential NTD reference laboratories have been recognized by way of systematic searches, snowball sampling and key informants. Results. 

Thirty-two laboratories responded to the survey. The laboratories coated 17 totally different NTDs and their major regional and nationwide roles have been to present technical help and coaching, analysis, check validation and normal setting.

Two thirds of the laboratories have been based mostly in tutorial establishments and nearly half had lower than 11 workers. Although higher than 90 per cent of the laboratories had sufficient technical expertise to operate as an NTD reference laboratory, nearly all laboratories lacked techniques for exterior verification that their outcomes met worldwide requirements. Conclusions. 

This research highlights that though many laboratories believed they may act as a reference laboratory, only some had all the traits required to fulfil this position as they fell quick in the normal and high quality assurance of laboratory processes.

Networks of prime quality laboratories are important for the management and elimination of illness and this research presents a essential first step in the growth of such networks for NTDs.