Chemistry, sustainability and naturality of perfumery biotech ingredients

Chemistry, sustainability and naturality of perfumery biotech ingredients

White biotechnology has emerged in biochemical manufacturing processes to ship perfumery ingredients satisfying novel pursuits of the society for pure, eco-responsible and sustainable supplies. As a consequence, an intense R&D exercise has taken place on these topics, leading to each scientific publications and patent functions reporting combos of state-of-the-art approaches in biocatalysis, metabolic engineering, artificial biology, biosynthesis elucidation, gene version and cloning, and analytical chemistry.

In this minireview, we current a smelly choice of novel biotechnological processes and ingredients from a scientific articles and patents survey protecting the final 6 years and analysed in phrases of chemistry, sustainability and naturalitysynthesis of important oil surrogates or single molecule ingredients, and on one other aspect the optimisation of properties of pure advanced substances by particular and selective enzymatic modifications of their chemical composition. Data had been confirmed, even evaluating luggage based on filling quantity. Data introduced on this research help the conclusion that CryoMACS freezing luggage are bioequivalent to Maco Biotech Freezing-EVA Bags for HPC cryopreservation.

The growing discoveries concerning the biology and capabilities of platelets within the final decade undoubtedly present that these cells are one of probably the most biotechnological human cells. This evaluate summarizes new advances in platelet biology, capabilities, and new ideas of biotech-educated platelets that join superior biomimetic science to platelet-based additive manufacturing for tissue regeneration. As extremely responsive and secretory cells, platelets may very well be explored to develop options that alter injured microenvironments by platelet-based artificial biomaterials with instructive extracellular cues for morphogenesis in tissue engineering past tissue regeneration 2.0.

Comparison of CryoMACS Freezing Bags with Maco Biotech Freezing-Ethinyl Vinyl Acetate Bags for Hematopoietic Progenitor Cells Cryopreservation Using a CD34 +-Enriched Product

Hematopoietic progenitor cells (HPCs) cryopreservation have functions, particularly within the autologous setting, permitting therapeutic use a number of years after assortment. Cryopreservation goals to protect the therapeutic properties of HPCs, and profitable cryopreservation will depend on a number of elements akin to preservation procedures, biopreservation media, freezing charges, and thawing procedures. In this context, the selection of the freezing bag is important because it offers mechanical safety through the freezing course of. Since Maco Biotech Freezing-ethinyl vinyl acetate (EVA) Bags® are now not obtainable in our nation, a comparative research was developed to confirm bioequivalence with the Miltenyi CryoMACS® freezing bag.

In this research, a CD34+-enriched product was used to higher reproduce HPC apheresis. Freezing luggage had been crammed with the identical quantity, cryopreserved with managed price freezing, and saved within the vapor part of liquid nitrogen for no less than 6 months. After thawing, all luggage had been examined for . Classification has been made between metabolic engineering on one aspect, permitting both biotechnological  integrity and sterility utilizing a microbial problem. In addition, a comparability was developed by evaluating restoration of white blood cells, mononuclear cells, lymphocytes, and CD34+ cells.No important variations between the 2 producers’ luggage have been noticed in phrases of the evaluated parameters.

This mini-review offers a perspective of conventional, rising and future functions of lactic acid micro organism (LAB) and how genome modifying instruments can be utilized to beat present challenges in all these functions. It additionally describes obtainable instruments and how these might be additional developed, and takes present laws under consideration. Genome modifying instruments are obligatory for the development of strains for brand spanking new functions and merchandise, however may play an important function in conventional ones, akin to meals and probiotics, as a analysis software for gaining mechanistic insights and discovering new properties.

Traditionally, recombinant DNA methods for LAB have strongly centered on being food-grade, however they lack velocity and the quantity of genetically tractable strains continues to be reasonably restricted. Further software growth will allow fast building of a number of mutants or mutant libraries on a genomic degree in all kinds of LAB strains. We additionally suggest an iterative Design-Build-Test-Learn workflow cycle for LAB cell manufacturing facility growth based mostly on techniques biology, with ‘cell manufacturing facility’ increasing past its conventional which means of manufacturing strains and making use of genome modifying instruments to advance LAB understanding, functions and pressure growth.

 Chemistry, sustainability and naturality of perfumery biotech ingredients

Microbe Profile: Komagataella phaffii: a methanol devouring biotech yeast previously generally known as Pichia pastoris

Methylotrophic yeasts of the genus Komagataella are abundantly present in tree exudates. Their potential to make the most of methanol as carbon and power supply depends on an assimilation pathway localized in largely expanded peroxisomes, and a cytosolic methanol dissimilation pathway. Other substrates like glucose or glycerol are readily utilized as effectively. Upon mating diploid cells sporulate readily, forming asci with 4 haploid spores. Their potential to secrete excessive quantities of heterologous proteins made them attention-grabbing for biotechnology, which expands as we speak additionally to different merchandise of major and secondary metabolism.

Polystyrene-bottomed 96-well plate (ELISA)

CT361 6
EUR 73

Adapter for 96 well plate

3510147 1unit
EUR 5581

Streptavidin coated 96-well Plate

6523-5
EUR 327

Black 96 Well Plate, 1EA

X025-1EA 1EA
EUR 73

96 well filter plate (960ul each well)

SD5006 12UNIT
EUR 96.54
  • Product category: Labware/Filtration Supplies/Filter Plates - DNA

96 WELL CLEAR PCR PLATE FOR ABI

PCR-96-AB-C 10/pk
EUR 167
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

1.2ML 96 WELL DEEP WELL PLATE HIGH CLARITY

P-DW-12-HC 5/pk
EUR 152
Description: Deep Well/Assay Plates - Axygen; Deep-well plates - Axygen

Clear Coated 96 Well Plate, 1EA

C107-1EA 1EA
EUR 189

96 well filter plate (no filter)

SD5006-EMPTY 12UNIT
EUR 87.41
  • Product category: Labware/Filtration Supplies/Filter Plates - DNA

Equine Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-Eq-48T 48T
EUR 360
  • Should the Equine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Equine Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Immunoglobulin G (IgG) ELISA Kit

DLR-IgG-Eq-96T 96T
EUR 457
  • Should the Equine Immunoglobulin G (IgG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Equine Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-Eq-48Tests 48 Tests
EUR 358

Equine Immunoglobulin G (IgG) ELISA Kit

RDR-IgG-Eq-96Tests 96 Tests
EUR 490

96 WELL SITTING DROP HIGH THROUGHPUT CRYSTALLOGRAPHY PLATE.

CP-AXYGEM-96-50 10/pk
EUR 457
Description: Crystallography Plates; Crystallography Plates - Axygen

96 WELL CLEAR PCR HALF SKIRT AMPLIFICATION PLATE

PCR-96-HS-C 10/pk
EUR 159
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 well DNA plate with membrane (960ul each well)

SD5007 12UNIT
EUR 242.7
  • Product category: Labware/Filtration Supplies/Filter Plates - DNA

96 well RNA plate with membrane (960ul each well)

SD5009 12UNIT
EUR 260.97
  • Product category: Labware/Filtration Supplies/Filter Plates - RNA

96 Well Breast Tumor Genomic DNA Plate

D8235086-1 1 plate
EUR 316

96 Well Colon Tumor Genomic DNA Plate

D8235090-1 1 plate
EUR 316

96 Well Lung Tumor Genomic DNA Plate

D8235152-1 1 plate
EUR 316

96 Well Stomach Tumor Genomic DNA Plate

D8235248-1 1 plate
EUR 316

Polystyrene-bottomed 96-well plate + lid (ELISPOT)

CT365 5
EUR 78

2 x Clear 96 well Plate, 2EA

X003-2EA 2EA
EUR 65

5 x Clear 96 well Plate, 5EA

X003-5EA 5EA
EUR 80

2 x Clear 96 well Plate, 2EA

X018-2EA 2EA
EUR 65

4 x Clear 96 Well Plate, 4EA

X018-4EA 4EA
EUR 87

Black Half Area 96 Well Plate, 1EA

X023-1EA 1EA
EUR 80

96-Well Plate PCR Products Purification Kit

BS365 5XPlates, 480prep
EUR 250.31
  • Product category: Molecular Biology Kits/DNA - Extraction/PCR Products

96-Well Plate PCR Products Purification Kit

BS3652 2xPlates, 192prep
EUR 155.16
  • Product category: Molecular Biology Kits/DNA - Extraction/PCR Products

96-Well Plate DNA Cleanup Miniprep Kit

BS369 5XPlates, 480prep
EUR 250.31
  • Product category: Molecular Biology Kits/DNA - Extraction/Clean-up

96-Well Plate DNA Cleanup Miniprep Kit

BS3692 2xPlates, 192prep
EUR 155.16
  • Product category: Molecular Biology Kits/DNA - Extraction/Clean-up

96-Well Plate Plasmid DNA Miniprep Kit

BS415 5XPlates, 480prep
EUR 250.31
  • Product category: Molecular Biology Kits/DNA - Extraction/Bacteria

96-Well Plate Plasmid DNA Miniprep Kit

BS4152 2XPlates, 192prep
EUR 155.16
  • Product category: Molecular Biology Kits/DNA - Extraction/Bacteria

96-Well Plate Viral DNA Miniprep Kit

VT92032 2XPlates, 192prep
EUR 413.22
  • Product category: Molecular Biology Kits/DNA - Extraction (Genomic)/Viral

Radius 96-Well Cell Migration Assay

CBA-126 96 assays
EUR 572
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

Radius 96-Well Cell Migration Assay

CBA-126-5 5 x 96 assays
EUR 2248
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

CytoSelect 96-well Cell Transformation Assay

CBA-130 96 assays
EUR 722
Description: Our CytoSelect 96-Well Cell Transformation Assay (Soft Agar Colony Formation) is suitable for measuring cell transformation where no downstream analysis is required. Cells are incubated in a semisolid agar medium for 7-8 days. The cells are then solubilized, lysed and detected using the included fluorescent dye in a fluorometric plate reader.

CytoSelect 96-well Cell Transformation Assay

CBA-130-5 5 x 96 assays
EUR 2886
Description: Our CytoSelect 96-Well Cell Transformation Assay (Soft Agar Colony Formation) is suitable for measuring cell transformation where no downstream analysis is required. Cells are incubated in a semisolid agar medium for 7-8 days. The cells are then solubilized, lysed and detected using the included fluorescent dye in a fluorometric plate reader.

CytoSelect 96-well Phagocytosis Assay (Zymosan)

CBA-224 96 assays
EUR 722
Description: Phagocytosis can be assayed by measuring the engulfment of a cell "substrate". However, traditional assays require tedious cell counting under a microscope. Our CytoSelect 96-Well Phagocytosis Assay, Zymosan Substrate provides a more accurate, user-friendly, high-throughput alternative to the standard phagocytosis assay. The assay may be adapted for use with 24-well or 48-well plates.

CytoSelect 96-well Phagocytosis Assay (Zymosan)

CBA-224-5 5 x 96 assays
EUR 2938
Description: Phagocytosis can be assayed by measuring the engulfment of a cell "substrate". However, traditional assays require tedious cell counting under a microscope. Our CytoSelect 96-Well Phagocytosis Assay, Zymosan Substrate provides a more accurate, user-friendly, high-throughput alternative to the standard phagocytosis assay. The assay may be adapted for use with 24-well or 48-well plates.

OxiSelect 96-Well Comet Assay Kit

STA-355 96 assays
EUR 427
Description: Our OxiSelect 96-Well Comet Assay Kits provide a higher-throughput way to screen for general DNA damage, regardless of the source or nature of the damage. Kits contain Comet Slides, reagents, and a fluorescent dye to visualize cells under an epifluorescence microscope.

OxiSelect 96-Well Comet Assay Kit

STA-355-5 5 x 96 assays
EUR 1633
Description: Our OxiSelect 96-Well Comet Assay Kits provide a higher-throughput way to screen for general DNA damage, regardless of the source or nature of the damage. Kits contain Comet Slides, reagents, and a fluorescent dye to visualize cells under an epifluorescence microscope.

OxiSelect 96-Well Comet Assay Slide

STA-356 1 slide
EUR 183
Description: The OxiSelect Comet Assay Slides are useful as a screening tool for various types of DNA damage. Slides are specially treated for adhesion of low-melting agarose. Easily visualize results by epifluorescence microscopy.

OxiSelect 96-Well Comet Assay Slide

STA-356-5 5 slides
EUR 519
Description: The OxiSelect Comet Assay Slides are useful as a screening tool for various types of DNA damage. Slides are specially treated for adhesion of low-melting agarose. Easily visualize results by epifluorescence microscopy.

96-Well ROCK Activity Assay Kit

STA-416 96 assays
EUR 856
Description: Rho-associated Kinase (ROCK) mediates Rho signaling and reorganizes the actin cytoskeleton by phosphorylation of several substrates that contribute to the assembly of actin filaments and contractility. ROCK inactivates myosin phosphatase through the specific phosphorylation of myosin phosphatase target subunit 1 (MYPT1) at Thr-696, which results in an increase in the phosphorylated content of the 20-kDa myosin light chain (MLC20). Our 96-Well ROCK Activity Assay Kit uses a safe, non-radioactive format to measure the level of active Rho Kinase in cell or tissue lysates. The kit contains a strip-well plate pre-coated with recombinant MYPT1.

96-Well ROCK Activity Assay Kit

STA-416-5 5 x 96 assays
EUR 3524
Description: Rho-associated Kinase (ROCK) mediates Rho signaling and reorganizes the actin cytoskeleton by phosphorylation of several substrates that contribute to the assembly of actin filaments and contractility. ROCK inactivates myosin phosphatase through the specific phosphorylation of myosin phosphatase target subunit 1 (MYPT1) at Thr-696, which results in an increase in the phosphorylated content of the 20-kDa myosin light chain (MLC20). Our 96-Well ROCK Activity Assay Kit uses a safe, non-radioactive format to measure the level of active Rho Kinase in cell or tissue lysates. The kit contains a strip-well plate pre-coated with recombinant MYPT1.

1.2ML 96 WELL DEEP WELL PLATE HIGH CLARITY PRE-STERILIZED

P-DW-12-HC-S 5/pk
EUR 207
Description: Deep Well/Assay Plates - Axygen; Deep-well plates - Axygen

SpotLiter? 96 well Plate Light Tracker (foot pedal & USB included)

ACT-SL-96
EUR 647

Block for 96 well plate, WSC-2620/30

4002659 1unit
EUR 382
Description: Bl ock for WSC-2620 / 2630

PVDF membrane-bottomed 96-well plate + lid (ELISPOT)

CT366 5
EUR 224

96-well Plasmid DNA Extraction Kit (1 plate)

FAPWE-96001 1 prep
EUR 146

96 Well Plate RNA Cleanup and Concentration Kit

BRC1251 2xPlates, 192prep
EUR 250.31
  • Product category: Molecular Biology Kits/RNA - Extraction/Clean-up

96-Well Plate Animal Genomic DNA Miniprep Kit

BS437 5XPlates, 480prep
EUR 362.98
  • Product category: Molecular Biology Kits/DNA - Extraction (Genomic)/Animal

96-Well Plate Animal Genomic DNA Miniprep Kit

BS4372 2XPlates, 192prep
EUR 195.5
  • Product category: Molecular Biology Kits/DNA - Extraction (Genomic)/Animal

96 Well Plate Yeast Genomic DNA Miniprep Kit

BS8357 2XPlates, 192prep
EUR 195.5
  • Product category: Molecular Biology Kits/DNA - Extraction (Genomic)/Yeast

96-Well Plate Plant Genomic DNA Miniprep Kit

BS8361 2XPlates, 192prep
EUR 195.5
  • Product category: Molecular Biology Kits/DNA - Extraction (Genomic)/Plant

96 Well Plate Blood Genomic DNA Miniprep Kit

BT92031 2Plates, 192prep
EUR 175.71
  • Product category: Molecular Biology Kits/DNA - Extraction (Genomic)/Blood

96 Well Plate Blood Genomic DNA Miniprep Kit

BT92032 5Plates, 480prep
EUR 324.92
  • Product category: Molecular Biology Kits/DNA - Extraction (Genomic)/Blood

96-Well Plate Bacteria Genomic DNA Miniprep Kit

SK1292 2XPlates, 192prep
EUR 175.71
  • Product category: Molecular Biology Kits/DNA - Extraction (Genomic)/Bacteria

96-Well Plate Bacteria Genomic DNA Miniprep Kit

SK1295 5XPlates, 480prep
EUR 324.92
  • Product category: Molecular Biology Kits/DNA - Extraction (Genomic)/Bacteria

96 Well ExoELISA plate (12x8 well strips, pack of 10 plates)

EXOEL-96P-1 10 Plates
EUR 213

CytoSelect 96-well Anoikis Assay (Colorimetric/Fluorometric)

CBA-081 96 assays
EUR 606
Description: Adhesion to the extraceullular matrix is essential for the survival and propagation of many adherent cells. Apoptosis resulting from the loss of adhesion to the ECM is known as anoikis. Anoikis is involved in the physiological processes of tissue renewal and cell homeostasis. Our CytoSelect Anoikis Assays allow you to quantify and monitor anoikis in cells using a precoated plate. Live cells can be viewed under a microscope and quantified on a plate reader by MTT (colorimetric) or Calcein AM (fluorometric); both reagents are included in the kit. Dead cells are detected with the red EthD-1 reagent, also included.

96-well Checkpoint Kinase Activity Assay Kit

STA-414 96 assays
EUR 757
Description: Our 96-well Checkpoint Kinase Activity Assay Kit provides a non-isotopic, sensitive and specific method to monitor checkpoint kinase activity using its physiological substrate; it can also be used in screening checkpoint kinase inhibitors.

96-well Checkpoint Kinase Activity Assay Kit

STA-414-5 5 x 96 assays
EUR 3060
Description: Our 96-well Checkpoint Kinase Activity Assay Kit provides a non-isotopic, sensitive and specific method to monitor checkpoint kinase activity using its physiological substrate; it can also be used in screening checkpoint kinase inhibitors.

96-Well Assay Plates, Non-Treated, Clear, Round Bottom 1 Plate/Pack, 100/Unit

25-224 100 plates
EUR 299
Description:

Suitable for cell culture but only for suspension cells

  • Optically clear with low autofluorescence for distortion free microscopy
  • Low evaporation lid reduces evaporation and prevents contamination
  • Exterior stacking ring on lid for added stability when stacking
  • Certified RNase & DNase-Free, Non-Pyrogenic & Non-Cytotoxic
  • Sterilized by Gamma Irradiation to a Sterility Assurance Level of 10^-10

Protein A-coated ELISA plate (8 well strips, 96 wells/plate) 5 plates/pack

PRTA55-5P 1 PK
EUR 263

Protein G-coated ELISA plate (8 well strips, 96 wells/plate) 5 plates/pack

PRTG65-5P 1 PK
EUR 263

CytoSelect 96-Well Hematopoietic Colony Forming Cell Assay (96 assays)

CBA-320 96 assays
EUR 537
Description: Hematopoietic stem cells (HSCs) are well-characterized, tissue-specific stem cells that are responsible for the lifelong maintenance of the hematopoietic system. HSCs or hematopoietic progenitors known as colony-forming cells (CFCs) proliferate to form discrete colonies when cultured in a suitable 3D environment, such as methylcellulose supplemented with nutrients and cytokines. Our CytoSelect 96-Well Hematopoietic Colony Forming Cell Assay promotes the formation of HSC colonies in just 7-10 days. Cells can then be either quantified in a fluorescence plate reader or recovered from the semisolid medium for further downstream analysis.

SINGLE BLOCK, 96 WELL PCR PLATE, SKIRTED OR NONSKIRTED

480130 1/pk
EUR 223
Description: Lab Equipment; Constant Temperature Equipment

DUAL BLOCK, 96 WELL MICROTITER PLATE OR 4 SLIDES

480131 1/pk
EUR 218
Description: Lab Equipment; Constant Temperature Equipment

DUAL BLOCK, 96 WELL PCR PLATE, SKIRTED OR NONSKIRTED

480132 1/pk
EUR 218
Description: Lab Equipment; Constant Temperature Equipment

COOLSINK XT 96U, 96 WELL U-BOTTOM PLATE MODULE

432071 1/pk
EUR 345
Description: BioCision; BioCision CoolBox

Block for 96 deep-well plate, WSC-2620/30

4002661 1unit
EUR 382
Description: Bl ock for WSC-2620 / 2630

Adaptor for 96-well PCR plate, accessory for AgileSealer?

APS-200-96PCR
EUR 351

Mouse anti-Osteopontin Clear Coated 96 Well Plate, 1EA

C075-1EA 1EA
EUR 178

Mouse anti-Myeloperoxidase Clear Coated 96 Well Plate, 1EA

C223-1EA 1EA
EUR 178

Mouse anti-Prolactin Clear Coated 96 Well Plate, 1EA

C140-1EA 1EA
EUR 178

96 Well PCR Plates, Fits ABI Fast Plate Machines

GP615 25 plates
EUR 212

Goat anti-Mouse, Coated White 96 Well Plate, 1EA

X010-1EA 1EA
EUR 109

Goat anti-Rabbit, Coated White 96 Well Plate, 1EA

X014-1EA 1EA
EUR 109

Goat anti-Rabbit, Coated Clear 96 Well Plate, 1EA

X016-1EA 1EA
EUR 109

2 x Black Half Area 96 Well Plate, 2EA

X037-2EA 2EA
EUR 94

Donkey anti-Sheep, Coated Clear 96 Well Plate, 1EA

X061-1EA 1EA
EUR 109

Donkey anti-Sheep, Coated White 96 Well Plate, 1EA

X063-1EA 1EA
EUR 109

96 Well Plate Bacterial Total RNA Miniprep Super Kit

BS585 5XPlates, 480prep
EUR 487.82
  • Product category: Molecular Biology Kits/RNA - Extraction/Bacteria

96 Well Plate Bacterial Total RNA Miniprep Super Kit

BS5852 2XPlates, 192prep
EUR 250.31
  • Product category: Molecular Biology Kits/RNA - Extraction/Bacteria

Ultra-Fast 96-Well Plate Plasmid DNA Miniprep Kit

BS92028 2XPlates, 192prep
EUR 212.25
  • Product category: Molecular Biology Kits/DNA - Extraction/Bacteria

Ultra-Fast 96-Well Plate Plasmid DNA Miniprep Kit

BS92029 5XPlates, 480prep
EUR 364.5
  • Product category: Molecular Biology Kits/DNA - Extraction/Bacteria

96 WELL BARCODED H1-H12, CLEAR PCR PLATE FOR ABI, 0,2ML

PCR-96-AB-C-PBC 10/pk
EUR 195
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

DH10B Chemically Competent Cells (ig10B) - 1x96 well plate - 20µl/well

1018-96 1/EA
EUR 518

CytoSelect 96-well Collagen Cell Invasion Assay, Fluorometric

CBA-112-COL 96 assays
EUR 757
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect 96-Well Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 96-well plates on a fluorescence plate reader. Inserts are precoated on the top of the membrane with Collagen I.

CytoSelect 96-well Laminin Cell Invasion Assay, Fluorometric

CBA-112-LN 96 assays
EUR 757
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect 96-Well Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 96-well plates on a fluorescence plate reader. Inserts are precoated on the top of the membrane with Laminin.

CytoSelect 96-well Phagocytosis Assay (Red Blood Cell)

CBA-220 96 assays
EUR 635
Description: Phagocytosis can be assayed by measuring the engulfment of a cell "substrate". However, traditional assays require tedious cell counting under a microscope. Our CytoSelect 96-Well Phagocytosis Assay, Red Blood Cell Substrate provides a more accurate, user-friendly, high-throughput alternative to the standard phagocytosis assay. The assay may be adapted for use with 24-well or 48-well plates.

96-well Cellular Senescence Assay (SA ?-Gal Activity)

CBA-231 120 assays
EUR 635
Description: Our Cellular Senescence Activity Assay provides an efficient method to measure Senescence Associated (SA) ß-galactosidase activity. SA-ß-Gal catalyzes the hydrolysis of X-gal, which produces a blue color in senescent cells. Quantify senescence using a fluorescence plate reader.

96-well Cellular Senescence Assay (SA ?-Gal Activity)

CBA-231-5 5 x 120 assays
EUR 2648
Description: Our Cellular Senescence Activity Assay provides an efficient method to measure Senescence Associated (SA) ß-galactosidase activity. SA-ß-Gal catalyzes the hydrolysis of X-gal, which produces a blue color in senescent cells. Quantify senescence using a fluorescence plate reader.

Clear 384 Well Plate

X105-1EA 1EA
EUR 112

Protein A&G-coated ELISA plate (8 well strips, 96 wells/plate) 5 plates/pack

PRTAG75-5P 1 PK
EUR 286

Goat anti-Mouse, 1 x Whole Well, Clear Coated 96 Well Plate, 1EA

X011-1EA 1EA
EUR 102

FALCON® 96 WELL CLEAR ROUND BOTTOM NOT TREATED ASSAY PLATE, NONSTERILE, 5/PACK, 50/CASE

353910 5/pk
EUR 91
Description: Assay - DL; Assay 96 well - DL

DNA-BIND™ PLATE, 96 WELL, CLEAR, FLAT 1/10

2525 1/pk
EUR 137
Description: Genomics; Genomic Plates

Mouse anti-Cystatin C Clear Coated 96 Well Plate, 1EA

C033-1EA 1EA
EUR 178

Mouse anti-Endothelin-1 Clear Coated 96 Well Plate, 1EA

C161-1EA 1EA
EUR 178

96-Well Plate Plasmid DNA Mini-Preps Kit (Vacuum Based)

B814152-0002 2XPlates, 2XPlates
EUR 155.16
  • Product category: Molecular Biology Kits/DNA - Extraction/Bacteria

96-Well Plate Plasmid DNA Mini-Preps Kit (Vacuum Based)

B814152-0005 5XPlates, 5XPlates
EUR 250.31
  • Product category: Molecular Biology Kits/DNA - Extraction/Bacteria

96 Well 0.2ml PCR Plate, Chimney-Top 10/Bag, Sterile

PCR-960-P-CH-S 1PK, 10UNIT
EUR 92.79
  • Product category: Labware/Multiwell Plates/96-Well

Sealing film, PCR 96 Well Plate Sealing Membrane, 100/pk

P1001-PCR 100/pack
EUR 95.9
Description: Sealing film PCR 96 Well Plate Sealing Membrane

CytoSelect 96-well Cell Migration Assay (3 ?m), Fluorometric

CBA-104 96 assays
EUR 635
Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 3 µm pore size is best for the smallest cells including neutrophils and other leukocytes.

CytoSelect 96-well Cell Migration Assay (3 ?m), Fluorometric

CBA-104-5 5 x 96 assays
EUR 2613
Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 3 µm pore size is best for the smallest cells including neutrophils and other leukocytes.

CytoSelect 96-well Cell Migration Assay (5 ?m), Fluorometric

CBA-105 96 assays
EUR 635
Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 5 µm pore size is ideal for monocytes / macrophages.

CytoSelect 96-well Cell Migration Assay (5 ?m), Fluorometric

CBA-105-5 5 x 96 assays
EUR 2613
Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 5 µm pore size is ideal for monocytes / macrophages.

CytoSelect 96-well Cell Migration Assay (8 ?m), Fluorometric

CBA-106 96 assays
EUR 635
Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 8 µm pore size is suitable for most cell types including epithelial cells, fibroblasts, and cancer cell lines.

CytoSelect 96-well Cell Migration Assay (8 ?m), Fluorometric

CBA-106-5 5 x 96 assays
EUR 2613
Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their environment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 8 µm pore size is suitable for most cell types including epithelial cells, fibroblasts, and cancer cell lines.

CytoSelect 96-Well Phagocytosis Assay (E. coli, Colorimetric Format)

CBA-222 96 assays
EUR 693
Description: Phagocytosis can be assayed by measuring the engulfment of a cell "substrate". However, traditional assays require tedious cell counting under a microscope. Our CytoSelect 96-Well Phagocytosis Assay, E. coli Substrate provides a more accurate, user-friendly, high-throughput alternative to the standard phagocytosis assay. The assay may be adapted for use with 24-well or 48-well plates.

CytoSelect 96-Well Phagocytosis Assay(Zymosan Substrate), Trial Size

CBA-224-T 20 assays
EUR 386
Description: Phagocytosis can be assayed by measuring the engulfment of a cell "substrate". However, traditional assays require tedious cell counting under a microscope. Our CytoSelect 96-Well Phagocytosis Assay, Zymosan Substrate provides a more accurate, user-friendly, high-throughput alternative to the standard phagocytosis assay. The assay may be adapted for use with 24-well or 48-well plates.

EZCellTM Cell Invasion Assay (laminin), 96-well, 8 µm

K914-100
EUR 566

Goat anti-Mouse, 1 x 8 Strip Well, Clear Coated 96 Well Plate, 1EA

X012-1EA 1EA
EUR 109

96 WELL CLEAR PCR MICROPLATE

PCR-96-C 10/pk
EUR 145
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

CytoSelect 96-Well Hematopoietic Colony Forming Cell Assay (5 x 96 assays)

CBA-320-5 5 x 96 assays
EUR 2114
Description: Hematopoietic stem cells (HSCs) are well-characterized, tissue-specific stem cells that are responsible for the lifelong maintenance of the hematopoietic system. HSCs or hematopoietic progenitors known as colony-forming cells (CFCs) proliferate to form discrete colonies when cultured in a suitable 3D environment, such as methylcellulose supplemented with nutrients and cytokines. Our CytoSelect 96-Well Hematopoietic Colony Forming Cell Assay promotes the formation of HSC colonies in just 7-10 days. Cells can then be either quantified in a fluorescence plate reader or recovered from the semisolid medium for further downstream analysis.

96 WELL BARCODED H1-H12, CLEAR PCR FULL SKIRT PCR AMPLIFICATION MICRO PLATE

PCR-96-FS-C-PBC 10/pk
EUR 168
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96-Well CometSlides

4253-096-03 1 Tests
EUR 142.4

Adapter for 24 well plate

3510146 1unit
EUR 5581

Random Nanofibers 24 Well Plate

3D00006-24 700 nm-PCLs
EUR 101

Targeted genome modifying is a sophisticated method that allows exact modification of the nucleic acid sequences in a genome. Genome modifying is usually carried out utilizing instruments, akin to molecular scissors, to chop an outlined location in a selected gene. Genome modifying has impacted numerous fields of biotechnology, akin to agriculture; biopharmaceutical manufacturing; research on the construction, regulation, and perform of the genome; and the creation of transgenic organisms and cell strains. Although genome modifying is used often, it has a number of limitations.

Here, we offer an outline of well-studied genome-editing nucleases, together with single-stranded oligodeoxynucleotides (ssODNs), transcription activator-like effector nucleases (TALENs), zinc-finger nucleases (ZFNs), and CRISPR-Cas9 RNA-guided nucleases (CRISPR-Cas9). To this finish, we describe the progress towards editable nuclease-based therapies and talk about the minimization of off-target mutagenesis. Future prospects of this difficult scientific area are additionally mentioned.  Komagataella yeasts normally develop as haploid cells and are secondary homothallic as they will change mating sort.

Green recycling process for polyurethane foams by a chem-biotech approach

Green recycling process for polyurethane foams by a chem-biotech approach

Polyurethanes are extremely resistant supplies used for constructing insulation or automotive seats. The polyurethane end-of-life situation should be addressed by the event of environment friendly recycling strategies. Since typical recycling processes usually are not appropriate for thermosets, waste administration of PU foam is especially questioning. By coupling organic and chemical processes, this research goals at creating a inexperienced recycling pathway for PU foam utilizing enzymes for depolymerization. For occasion, enzymatic degradation of a PU foam synthesized with polycaprolactone and toluene diisocyanate led to a weight lack of 25 % after 24 h of incubation.

The corresponding degradation merchandise have been recovered and recognized as 6-hydroxycaproic acid and a quick acid-terminated diurethane. An organo-metallic catalyzed synthesis of second technology polymers from these constructing blocks was carried out. A polymer with a excessive common molar mass of 74 000 (Mw) was obtained by mixing 50 % of recycled constructing blocks and 50 % of neat 6-hydroxycaproic acid. A poly(ester urethane) have been synthesized with out using poisonous and decrier polyisocyanates. It is the primary time that a research presents the imaginative and prescient of a recycling loop ranging from PU wastes and ending with a second technology polymer in a full round approach

mRNA applied sciences have the potential to remodel areas of medication, together with the prophylaxis of infectious ailments. The benefits for vaccines vary from the acceleration of immunogen discovery to speedy response and a number of illness goal manufacturing. A higher understanding of high quality attributes that dictate translation effectivity, in addition to a complete appreciation of the significance of mRNA supply, are influencing a new period of funding in growth actions. The utility of translational sciences and rising early-phase scientific expertise proceed to tell candidate vaccine choice. Here we evaluation the state-of-the-art for the prevention of infectious ailments by utilizing mRNA and pertinent matters to the biotechnology and pharmaceutical industries.

Quadrivalent Influenza Vaccine (Sinovac Biotech) for seasonal influenza prophylaxis

Quadrivalent Influenza Vaccine (Sinovac Biotech) is a quadrivalent split-virion inactivated influenza vaccine authorized in China in June 2020 for people ≥three years of age. It comprises 15 µg hemagglutinin per pressure together with A/H1N1, A/H3N2, B/Victoria, and B/Yamagata, which might probably enhance safety in opposition to influenza B viruses. In this evaluation, we summarize the event of quadrivalent influenza vaccines in China and overseas nations, and assess the immunogenicity and security from the section I and III scientific trials of Quadrivalent Influenza Vaccine in people ≥three years of age. We additionally talk about the potential utility of Quadrivalent Influenza Vaccine in younger kids 6-35 months of age based on the outcomes of the section III trial.
The immunogenicity and security profiles of Quadrivalent Influenza Vaccine containing two A and two B strains have been corresponding to the trivalent vaccines for the shared strains. The addition of a second B pressure to the trivalent vaccine might induce superior immune responses for the alternate B pressure. Since the 2 B strains co-circulated worldwide, the introduction of quadrivalent influenza vaccines has been anticipated to be a cost-effective technique. We in contrast the monetary efficiency of 319 BIOTECH corporations targeted on creating therapeutics with IPOs from 1997-2016, to that of paired, non-biotech CONTROL corporations with concurrent IPO dates. Both cohorts exhibited a high-risk/excessive reward sample of return, with the bulk shedding worth, however many reaching progress multiples. 
BIOTECH corporations had a distinctly totally different monetary construction with excessive R&D expense, little income, and unfavorable income (losses), however a comparable length of itemizing on public markets and frequency of acquisitions. Through 2016, BIOTECH and CONTROL corporations had equal progress in market cap and shareholder worth (>$100 billion), however BIOTECH corporations had decrease internet worth creation ($93 billion vs $411 billion). While investments in biotechnology are sometimes thought-about to be distinctively dangerous, we conclude that worth creation by biotech corporations after IPO resembles that of non-biotech corporations at a comparable stage and doesn’t current a disproportionate funding threat.
Green recycling process for polyurethane foams by a chem-biotech approach

Swiss Startup Framework: A Highly Effective Network Supporting the Generation of Emerging Biotech Businesses

For over 50 years, Switzerland has been one of many main nations driving innovation in biotechnology and its industrial purposes. Today, some 1,000 biotech corporations kind a tightly knit, cross-functional community starting from analysis by means of to manufacturing. This community contains R&D corporations, contract analysis organizations, and extremely specialised advisors and biotech traders. Together, they kind an exterior innovation pool that enhances the in-house R&D capability of the massive multi-national pharma corporations. A extremelyefficient startup framework, strong acceleration mechanisms, and progressive traders allow the emergence of a steady stream of biotech startups that revitalize the trade with new applied sciences and merchandise supporting drug growth and diagnostics.

PicoProbe Phosphate Assay Kit

55R-1403 100 assays
EUR 621
Description: Assay Kit for detection of Phosphate in the research laboratory

Phosphate Fluorometric Assay Kit

55R-1404 100 assays
EUR 438
Description: Assay Kit for detection of Phosphate in the research laboratory

QuantiChrom Phosphate Assay Kit

DIPI-500 500
EUR 372
Description: Quantitative determination of phosphate by colorimetric (620nm) method. Procedure: 30 min. Kit size: 500 tests. Detection limit: 3 µg/dL (0.3 µM). Shelf life: 12 months. Shipping: ambient temp; storage: 4°C.

Phosphate Assay Kit (Fluorometric)

K420-100
EUR 349

Phosphate Colorimetric Assay Kit

K410-500
EUR 316

Phosphate Colorimetric Assay Kit

k2074-500 500 assays
EUR 293

Phosphate Assay Kit (Fluorometric)

K2076-100 100 assays
EUR 363

PiBlue Phosphate Assay Kit

POPB-500 500
EUR 254
Description: High-throµghput phosphate assay using malachite green method at 620nm. Kit size: 500 tests. Detection limit: 0.4 µM. Shelf life: 12 months. Shipping: ambient temp; storage: 4°C.

Phosphate Assay Kit (Fluorometric)

STA-686 1000 assays
EUR 485
Description: Our Phosphate Assay Kit (Fluorometric) measures total inorganic phosphate present in lysates, solutions, food, or biological samples in a 96-well fluorescence-based plate reader. 1000 assays/kit.

PBlue Phosphate Assay Kit

Z5030013 500 assays
EUR 389
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

Glucose-6-Phosphate Assay Kit

55R-1487 100 assays
EUR 706
Description: Assay Kit for detection of Glucose-6-Phosphate in the research laboratory

Sucrose Phosphate Synthase Assay Kit

abx298805-100Assays 100 Assays
EUR 629
  • Shipped within 5-10 working days.

Malachite Green Phosphate Assay Kit

abx298878-100Assays 100 Assays
EUR 378
  • Shipped within 5-10 working days.

PicoProbe? Phosphate Fluorometric Assay Kit

K419-100
EUR 446

Malachite Green Phosphate Assay Kit

POMG-25H 2500
EUR 275
Description: High-throµghput phosphate assay using malachite green method at 620nm. Kit size: 2500 tests. Detection limit: 0.02 µM. Shelf life: 12 months. Shipping: ambient temp; storage: 4°C.

Malachite Green Phosphate Assay Kit

Z5030012 2,500 assays
EUR 342
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

Phosphoprotein Phosphate Estimation Assay Kit

BSP061 2000Assays, 2000preps
EUR 91.76
  • Product category: Molecular Biology Kits/Protein - Assays/Phosphorylation based

MESG *Phosphate assay reagent*

21600 5 mg
EUR 115
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

PicoProbe Glucose-6-Phosphate Assay Kit

55R-1495 100 assays
EUR 758
Description: Assay Kit for detection of Glucose-6-Phosphate in the research laboratory

PicoProbe Fructose-6-Phosphate Assay Kit

55R-1496 100 assays
EUR 758
Description: Assay Kit for detection of Fructose-6-Phosphate in the research laboratory

Glucose-6-Phosphate Dehydrogenase Assay Kit

55R-1520 100 assays
EUR 706
Description: Assay Kit for detection of Glucose-6-Phosphate Dehydrogenase in the research laboratory

EnzyChrom Glucose-6-Phosphate Assay Kit

EG6P-100 100
EUR 405
Description: For quantitative colorimetric determination of Glucose-6-Phosphate concentration and evaluation of drug effects on its metabolism. Method: OD460nm. Samples: plasma, serum,tissue and culture media etc. Species: all. Procedure: 20 min. Size: 100 tests. Dete

Glucose-6-Phosphate Dehydrogenase Assay Kit

abx298812-100Assays 100 Assays
EUR 425
  • Shipped within 5-10 working days.

Glucose-6-Phosphate Colorimetric Assay Kit

K657-100
EUR 512

Glucose-1-Phosphate Colorimetric Assay Kit

K697-100
EUR 550

Glucose-6-Phosphate Colorimetric Assay Kit

K2208-100 100 assays
EUR 529

Glucose-6-Phosphate Fluorometric Assay Kit

K2220-100 100 assays
EUR 599

Fructose-6-Phosphate Fluorometric Assay Kit

K2222-100 100 assays
EUR 599

PicoProbe? Glucose-6-Phosphate Fluorometric Assay Kit

K687-100
EUR 550

PicoProbe? Fructose-6-Phosphate Fluorometric Assay Kit

K689-100
EUR 550

Glycerol-3-Phosphate (G3P) Colorimetric Assay Kit

K641-100
EUR 544

PicoProbe? Dihydroxyacetone Phosphate (DHAP) Fluorometric Assay Kit

K673-100
EUR 773

PicoProbeTM Glycerol-3-Phosphate Assay Kit (Fluorometric)

K196-100
EUR 566

Glycerol-3-Phosphate (G3P) Assay Kit (Colorimetric)

MET-5075 100 assays
EUR 473

Glycerol-3-Phosphate (G3P) Assay Kit (Fluorometric)

MET-5076 100 assays
EUR 508

PhosphoWorks™ Fluorimetric Phosphate Assay Kit *Red Fluorescence*

21660 125 Tests
EUR 306
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

PhosphoWorks™ Colorimetric Phosphate Assay Kit *Blue Color*

21665 1000 Tests
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Amplite™ Fluorimetric Glucose-6-Phosphate Assay Kit

13804 200 Tests
EUR 306
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Amplite™ Colorimetric Glucose-6-Phosphate Assay Kit

13805 200 Tests
EUR 306
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Glucose-6-Phosphate Dehydrogenase Activity Colorimetric Assay Kit

K757-100
EUR 512

Triose Phosphate Isomerase (TPI) Activity Colorimetric Assay Kit

K670-100
EUR 653

Glycerol-3-Phosphate Dehydrogenase Activity Colorimetric Assay Kit

K640-100
EUR 653

Glucose-6-Phosphate Dehydrogenase Activity Colorimetric Assay Kit

K2172-100 100 assays
EUR 516

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Activity Assay Kit

MET-5078 200 assays
EUR 508

Glucose-6-Phosphate Dehydrogenase (G6PDH) Activity Assay Kit

MET-5081 100 assays
EUR 392

PhosphoWorks™ Colorimetric MESG Phosphate Assay Kit *UV absorption*

21659 200 Tests
EUR 306
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Amplite™ Fluorimetric Glycerol 3-Phosphate (G3P) Assay Kit

13837 200 Tests
EUR 350
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Amplite™ Colorimetric Glycerol 3-Phosphate (G3P) Assay Kit

13838 200 Tests
EUR 350
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

PicoProbe? Glucose-6-Phosphate Dehydrogenase Activity Assay Kit (Fluorometric)

K751-100
EUR 620

PPDK (Pyruvate, phosphate dikinase) Activity Assay Kit (Fluorometric/Colorimetric)

K456-100
EUR 479

Amplite™ Fluorimetric Glucose-6-Phosphate Dehydrogenase (G6PD) Assay Kit

13806 200 Tests
EUR 306
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Amplite™ Colorimetric Glucose-6-Phosphate Dehydrogenase (G6PD) Assay Kit

13807 200 Tests
EUR 306
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Frit Kit

FRIT-KIT 1each
EUR 124
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Column Packing Kit

PACK-KIT 1pack
EUR 1035
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 266

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1110
  • Category: Cas9

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV100PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV105PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV120PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV125PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS700A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS720A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS740A-KIT 10 rxn
EUR 1132
  • Category: Cas9

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)

CAS510A-KIT 1 Kit
EUR 805
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV200PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV205PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV220PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV225PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Glycosaminoglycans Assay Kit

6022 1 kit
EUR 419.75
Description: Glycosaminoglycans Assay Kit

DNA Assay Kit

6023 1 kit
EUR 180.5
Description: DNA Assay Kit

Hemoglobin Assay Kit

6024 1 kit
EUR 180.5
Description: Hemoglobin Assay Kit

Proteasome Assay Kit

55R-1341 100 assays
EUR 654
Description: Assay Kit for detection of Proteasome in the research laboratory

Calpain Assay Kit

55R-1342 100 assays
EUR 779
Description: Assay Kit for detection of Calpain in the research laboratory

Glutathione Assay Kit

55R-1343 100 assays
EUR 654
Description: Assay Kit for detection of Glutathione in the research laboratory

Glutathione Assay Kit

55R-1354 100 assays
EUR 895
Description: Assay Kit for detection of Glutathione activity in the research laboratory

HDAC Assay Kit

55R-1371 100 assays
EUR 673
Description: Assay Kit for detection of HDAC in the research laboratory

HDAC Assay Kit

55R-1372 100 assays
EUR 673
Description: Assay Kit for detection of HDAC in the research laboratory

HAT Assay Kit

55R-1373 100 assays
EUR 740
Description: Assay Kit for detection of HAT in the research laboratory

SOD Assay Kit

55R-1374 100 assays
EUR 602
Description: Assay Kit for detection of SOD in the research laboratory

HDAC3 Assay Kit

55R-1377 100 assays
EUR 693
Description: Assay Kit for detection of HDAC3 in the research laboratory

HDAC8 Assay Kit

55R-1379 100 assays
EUR 689
Description: Assay Kit for detection of HDAC8 in the research laboratory

ATP Assay Kit

55R-1380 100 assays
EUR 809
Description: Assay Kit for detection of ATP in the research laboratory

ADP Assay Kit

55R-1381 100 assays
EUR 809
Description: Assay Kit for detection of ADP in the research laboratory

FAD Assay Kit

55R-1382 100 assays
EUR 732
Description: Assay Kit for detection of FAD in the research laboratory

PEP Assay Kit

55R-1384 100 assays
EUR 876
Description: Assay Kit for detection of PEP in the research laboratory

Ammonia Assay Kit

55R-1388 100 assays
EUR 740
Description: Assay Kit for detection of Ammonia in the research laboratory

cAMP Assay Kit

55R-1389 100 assays
EUR 706
Description: Assay Kit for detection of cAMP activity in the research laboratory

cGMP Assay Kit

55R-1390 100 assays
EUR 706
Description: Assay Kit for detection of cGMP activity in the research laboratory

Urea Assay Kit

55R-1391 100 assays
EUR 740
Description: Assay Kit for detection of Urea in the research laboratory

Calcium Assay Kit

55R-1392 250 assays
EUR 586
Description: Assay Kit for detection of Calcium activity in the research laboratory

Magnesium Assay Kit

55R-1393 100 assays
EUR 654
Description: Assay Kit for detection of Magnesium in the research laboratory

Zinc Assay Kit

55R-1394 100 assays
EUR 673
Description: Assay Kit for detection of Zinc in the research laboratory

Iron Assay Kit

55R-1395 100 assays
EUR 758
Description: Assay Kit for detection of Iron in the research laboratory

JNK Assay Kit

55R-1407 40 assays
EUR 868
Description: Assay Kit for detection of JNK in the research laboratory

JNK Assay Kit

55R-1408 40 assays
EUR 979
Description: Assay Kit for detection of JNK in the research laboratory

Akt Assay Kit

55R-1409 40 assays
EUR 979
Description: Assay Kit for detection of Akt in the research laboratory

Ammonia Assay Kit

55R-1410 100 assays
EUR 740
Description: Assay Kit for detection of Ammonia in the research laboratory

Cobalt Assay Kit

55R-1435 100 assays
EUR 621
Description: Assay Kit for detection of Cobalt in the research laboratory

Nickel Assay Kit

55R-1436 100 assays
EUR 621
Description: Assay Kit for detection of Nickel in the research laboratory

Chloride Assay Kit

55R-1437 100 assays
EUR 484
Description: Assay Kit for detection of Chloride in the research laboratory

Aspartate Assay Kit

55R-1438 100 assays
EUR 673
Description: Assay Kit for detection of Aspartate in the research laboratory

Hydroxyproline Assay Kit

55R-1439 100 assays
EUR 844
Description: Assay Kit for detection of Hydroxyproline in the research laboratory

Phenylalanine Assay Kit

55R-1442 100 assays
EUR 654
Description: Assay Kit for detection of Phenylalanine in the research laboratory

Phosphatidylcholine Assay Kit

55R-1443 100 assays
EUR 673
Description: Assay Kit for detection of Phosphatidylcholine in the research laboratory

Glucose Assay Kit

55R-1449 100 assays
EUR 706
Description: Assay Kit for detection of Glucose in the research laboratory

Lactate Assay Kit

55R-1450 100 assays
EUR 844
Description: Assay Kit for detection of Lactate in the research laboratory

Pyruvate Assay Kit

55R-1452 100 assays
EUR 844
Description: Assay Kit for detection of Pyruvate in the research laboratory

Adipogenesis Assay Kit

55R-1454 100 assays
EUR 586
Description: Assay Kit for detection of Adipogenesis in the research laboratory

Glucose Assay Kit

55R-1458 100 assays
EUR 740
Description: Assay Kit for detection of Glucose in the research laboratory

Galactose Assay Kit

55R-1459 100 assays
EUR 740
Description: Assay Kit for detection of Galactose in the research laboratory

Maltose Assay Kit

55R-1460 100 assays
EUR 723
Description: Assay Kit for detection of Maltose in the research laboratory

Fructose Assay Kit

55R-1461 100 assays
EUR 689
Description: Assay Kit for detection of Fructose in the research laboratory

Ethanol Assay Kit

55R-1462 100 assays
EUR 774
Description: Assay Kit for detection of Ethanol in the research laboratory

Galactose Assay Kit

55R-1463 100 assays
EUR 706
Description: Assay Kit for detection of Galactose in the research laboratory

Lactose Assay Kit

55R-1466 100 assays
EUR 706
Description: Assay Kit for detection of Lactose in the research laboratory

Creatinine Assay Kit

55R-1467 100 assays
EUR 638
Description: Assay Kit for detection of Creatinine in the research laboratory

Sucrose Assay Kit

55R-1468 100 assays
EUR 689
Description: Assay Kit for detection of Sucrose in the research laboratory

Lactate Assay Kit

55R-1469 100 assays
EUR 844
Description: Assay Kit for detection of Lactate in the research laboratory

Maltose Assay Kit

55R-1470 100 assays
EUR 706
Description: Assay Kit for detection of Maltose in the research laboratory

Glutamate Assay Kit

55R-1471 100 assays
EUR 740
Description: Assay Kit for detection of Glutamate in the research laboratory

Fumarate Assay Kit

55R-1475 100 assays
EUR 706
Description: Assay Kit for detection of Fumarate in the research laboratory

Creatine Assay Kit

55R-1476 100 assays
EUR 654
Description: Assay Kit for detection of Creatine in the research laboratory

Sarcosine Assay Kit

55R-1477 100 assays
EUR 654
Description: Assay Kit for detection of Sarcosine in the research laboratory

Malate Assay Kit

55R-1478 100 assays
EUR 673
Description: Assay Kit for detection of Malate in the research laboratory

Glycogen Assay Kit

55R-1481 100 assays
EUR 844
Description: Assay Kit for detection of Glycogen in the research laboratory

Starch Assay Kit

55R-1482 100 assays
EUR 673
Description: Assay Kit for detection of Starch in the research laboratory

Alanine Assay Kit

55R-1483 100 assays
EUR 654
Description: Assay Kit for detection of Alanine in the research laboratory

Formate Assay Kit

55R-1484 100 assays
EUR 809
Description: Assay Kit for detection of Formate in the research laboratory

Citrate Assay Kit

55R-1485 100 assays
EUR 740
Description: Assay Kit for detection of Citrate in the research laboratory

Isocitrate Assay Kit

55R-1486 100 assays
EUR 663
Description: Assay Kit for detection of Isocitrate in the research laboratory

Oxaloacetate Assay Kit

55R-1488 100 assays
EUR 663
Description: Assay Kit for detection of Oxaloacetate in the research laboratory

Heme Assay Kit

55R-1492 100 assays
EUR 673
Description: Assay Kit for detection of Heme in the research laboratory

The age of immuno-oncology has ushered in a rush inside the biopharmaceutical trade. This intense focus has been characterised as a frenzy or overhyped, however represents a substantial funding in new merchandise that hope to harness the immune system in opposition to most cancers. Such brokers embrace next-generation checkpoint antagonists, immune costimulatory agonists, and a numerous array of novel mechanisms of motion and therapeutic modalities concentrating on immune cell varieties and the interaction of the host and tumor on the immune synapse. This article surveys the scientific growth and funding exercise with Immuno-Oncology, particularly prostate, kidney, and bladder cancers.

Novel coronavirus (2019-nCoV)

The recent emergence of a novel coronavirus (2019-nCoV), which caused an outbreak of unusual viral pneumonia in tens of people in Wuhan, a central city of China, restated the risk of coronaviruses posed to public health. In this mini-review, we give a brief introduction of the general features of coronaviruses and describe various diseases caused by different coronaviruses in humans and animals. This review will help understand the biology and potential risk of coronaviruses that exist in richness in wildlife such as bats.

2019-nCoV qPCR Kit

Novel Coronavirus (2019-nCoV) Real Time RT-PCR Kit



Nucleic Acid:RNA
Packing (tests/kit):25

Product Details

Cat.# Instrument* Quantity Price
RR-0478-02 Ⅲ,Ⅳ – 25 primer sets 1250 Euro Gentaur

Protocol for nCorV rt-pcr detection

  • Ⅰ:LightCycler 1.0 (Internal control can’t be used for this system)
  • Ⅱ:LightCycler 2.0
  • Ⅲ:PE5700, MJ-Opticon & other single color systems
  • Ⅳ:ABI7000, ABI7300, ABI7500, ABI7900, ABI StepOne, StepOne plus, MJ-Opticon2, MJ-chromo4, MX3000P, MX3005P, Smart Cycler II, Rotor-Gene 6000, LightCycler 480, CFX 96, Life 96, Slan 96, iCycler iQ4, iCycler iQ5 & other multi-color systems

NatTrol Control solution

nCorV Rna extraction

Novel Coronavirus (2019-nCoV) Real Time Multiplex RT-PCR Kit is used for the qualitative detection of a novel coronavirus, which was identified in 2019 at Wuhan City, Hubei Province, China, in upper respiratory tract specimens (nasopharyngeal extracts, deep cough sputum, etc.)

Identification of nCorV Rna

On January 11, 2020, Chinese health authorities preliminary identified more than 40 human infections with a novel corona-virus in an outbreak of pneumonia under investigation in Wuhan City, Hubei Province, China. The Chinese authorities identified a new type of corona virus (novel coronavirus,named as 2019-nCoV), which was isolated on 7 January 2020. Corona-viruses are a large family of viruses, some causing illness in human and others circulating among animals such as camels, cats and bats. 2019-nCoV is a novel corona virus. The primer and probe design for this kit is based on the newly released strain (2019-nCoV) (GeneBank accession: MN908947) and covers 6 2019-nCoV strains sequences (EPI_ISL_402119, EPI_ISL_402120, EPI_ISL_402121,EPI_ISL_402122,EPI_ISL_402123, EPI_ISL_402124included). The kit contains a specific ready-to-use system for the detection of Novel Corona virus (2019-nCoV) by Reverse transcription Polymerase Chain Reaction (RT-PCR) in the real-time PCR system. The master contains a Super Mix forthe specific amplification of virus RNA. The reaction is done inone step real time RT-PCR. The first step is a reverse transcription (RT), during which the virus RNAis transcribed into cDNA. Afterwards, a thermostable DNApolymerase is used to amplify the specific gene fragments by means of polymerase chain reaction (PCR). Fluorescence is emitted and measured by the real time systems´ optical unit during PCR. The detection of amplified virus DNA fragment is performed in fluorimeter channel FAM, HEX/VIC/JOE and Cal Red 610/ ROX/TEXASRED with the fluorescentquencher BHQ1.

The principle of the real-time detection is based on the fluorogenic 5’nuclease assay. During the PCR reaction, the DNA polymerase cleaves the probe at the 5’ end and separates the reporter dye from the quencher dye only when the probe hybridizes to the target DNA. This cleavage results in the fluorescent signal generated by the cleaved reporter dye, which is monitored real-time by the PCR detection system. The PCR cycle at which an increase in the fluorescence signal is detected initially (Ct) is proportional to the amount of the specific PCR product. Monitoring the fluorescence intensities in real time allows the detection

(2019-nCoV) Real Time Multiplex RT-PCR Kit

Novel Coronavirus (2019-nCoV) Real Time Multiplex RT-PCR Kit (Detection for 3 Genes )


Nucleic Acid:RNA
Packing (tests/kit):25 Inquiry
(Under Development)

Product Details


Cat.# Instrument* Quantity Price
RR-0479-02 Ⅲ,Ⅳ 1 primer set 1250 euro from Gentaur

Thermo-cyclers list

  • Ⅰ:LightCycler 1.0 (Internal control can’t be used for this system)
  • Ⅱ:LightCycler 2.0
  • Ⅲ:PE5700, MJ-Opticon & other single color systems
  • Ⅳ:ABI7000, ABI7300, ABI7500, ABI7900, ABI StepOne, StepOne plus, MJ-Opticon2, MJ-chromo4, MX3000P, MX3005P, Smart Cycler II, Rotor-Gene 6000, LightCycler 480, CFX 96, Life 96, Slan 96, iCycler iQ4, iCycler iQ5 & other multi-color systems 
  • V Cepheid GenExpert

Positive Control:

Coronavirus NatTrol

Other NatTrols

Carry Lam explaining the importance of early nCorV detection to increase prevention efficiency
Carry Lam explaining the importance of early nCorV detection to increase prevention efficiency

What infections can you expect in European Airports in 2020?

Are there risks of epidemics breaking out in the holliday season in Europe in 2020?

Incidentally, it remains difficult to prove causality, because Western Europeans will travel so often to tropical countries in 2020.

Infections present in Europe through tourism are West Nile Fever, dengue fever (dengue), infections by ricketsiae, and not to be missed: Entamoeba histolitica.

What deseases are unlikely to contaminate European Airports?

You shouldn’t immediately fear Ebola either. HIV, that depends on which cup you put your cookie on … AND then you are more likely to have hepatitis B or C.

Can traveling within Europe be a health risk too?

The ecology of Europe is changing. In 2020 we are getting more and more risk of a local fox tapeworm infection (never eat low blackberries in an area where foxes live).

Can I eat fresh fish in Europe in 2020?

There is also the herring worm that you can incur when eating Dutch or Danish “maatjes” or raw herring.

There is Listeria in 2020 that can also occur in smoked fish (!!!) Not only artisannal French or Italian cheese or dried meat products are known to possibly contain since long Listeria.

Is there a risk of Cholera or Typhus in Europe in 2020?

Cholera, typhoid fever and plague will stay out of Europe for the time being. There was a Cholera outbreack in Algeria in 2019 through vegetables irrigated with contaminated sewage water of toilets.

Zika virus could always be related to traveling in South America. Europe is endemic Zika free in 2020.

Pork is relatively safe in Europe in 2020 … even for roundworms … (Relative !!! ).

What will be the risk of Lime disease or Borelliosis travelling in 2020 in Europe?

Borreliosis (Lyme disease) is also on the rise again in Souther Belgium, France, Germany. Never walk barefeet or with sandals in grass during the 2020 summer if foxes or wild boar are known in the area. We advide high walking shoes with high socks or high walking boots or wellies. Neoprene wellies are easier to walk on long distances in nature. Not all teaks are contaminated with Lime disease. If you see after a bite a double circle around the biting area within 2 days you should consult a doctor for Pcr diagnosis of Borellia.

Is there a risk of Tuberculosis in Europe?

Tuberculosis fast testing with Ultra sensitive ELisa

Worse is tuberculosis in Eastern, Western Europe, India and Noth Africa. Both Mycobacterium tuberculosis and M. bovis appear to be in resurgence in 2020. Tuberculosis strains are often antibiotic resistant and a Gentaur spoligotyping test can very fast determine what antibiotic to take.

How often do I have to wash my hands traveling in Europe?

Imortant to know: every bacterium has a ‘porte d’entrée’, a minimal infectious population of intake (which is in combined to the individual immunity of ‘the victim). Washing more often your hands when traveling through European Airport Hubs is advisable in 2020.

With staphylococci and streptococci & co, the minimal number of bacteria that can only infect you are quite high: 10 e3 to 10 e5. Less than 1000 to 100 000 bacteria wil not infect you. Washing hands often is advised because Staphylococcus Aureus or the hospital bacteria is getting more and more antibiotic resistant. Multi Drug Resistant S. Aureus is especially dangerouse when you are travelling with an open wound. Cover the wound and wash your hands often.

For Mycobacteria you need only 1 (one) bacterium to get infected. Especially dangerouse after your trip because they take a long time to come to symptoms … But then you are really in trouble.

This aricle is written by:

Lieven Gevaert, bio-engineer at Gentaur Institute and frequent traveller.