The challenges and future of oral drug delivery: An interview with David Brayden.

David Brayden speaks to Hannah Makin, Commissioning Editor: David Brayden is a Full Professor (Advanced Drug Delivery) at the School of Veterinary Medicine, University College Dublin (UCD) and also a Fellow of the UCD Conway Institute.

Following a PhD in Pharmacology at the University of Cambridge, UK (1989), and a postdoctoral research fellowship at Stanford University, CA, USA, he set up Elan Biotechnology Research’s in vitro pharmacology laboratory in Dublin (1991).

At Elan, he became a senior scientist and project manager of several of Elan’s joint-venture drug delivery research collaborations with US biotech companies. In 2001, he joined UCD as a lecturer in veterinary pharmacology and was appointed Associate Professor in 2006 and Full Professor in 2014.

He was a Director of the Science Foundation Ireland Research Cluster (The Irish Drug Delivery ResearchNetwork) from 2007 to 2013, is a Deputy Coordinator of an FP7 Consortium on oral peptides in nanoparticles (‘TRANS-INT’, 2012-2017), and is a Co-Principal Investigator in ‘CURAM’, Science Foundation Ireland’s new Centre for Medical Devices (2014-2020 [ 1 ]).

He was made a Fellow of the Controlled Release Society in 2012. He is the author or co-author of>>200 research publications and patents.

D Brayden serves on the Editorial Advisory Boards of Drug Discovery Today, European Journal of Pharmaceutical Sciences, Advanced Drug Delivery Reviews and the Journal of Veterinary Pharmacology and Therapeutics, and is an Associate Editor of Therapeutic Delivery.

AKR/12B-2

ABC-TC205S 1 vial Ask for price
Description: Tissue: thymus; Transformed by: X-rays. The cells express Lyt-2, Lyt-3 and CD4 in the cytosol, but not on the membrane; They reexpress Lyt-2, Lyt-3 and CD4 on the membrane after sorting by magnetic particles (5 cycles).

AKR/12B-3

ABC-TC206S 1 vial Ask for price
Description: Tissue: thymus; Transformed by: X-rays. The cells express Lyt-2, Lyt-3 and CD4 in the cytosol, but not on the membrane; They do not reexpress Lyt-2, Lyt-3 and CD4 on the membrane after sorting by magnetic particles (5 cycles).

CCI-006

462390 5.0mg
EUR 530

LYS-006

555854 50.0mg
EUR 1250

CCI-006

T10706-10mg 10mg Ask for price
Description: CCI-006

CCI-006

T10706-1g 1g Ask for price
Description: CCI-006

CCI-006

T10706-1mg 1mg Ask for price
Description: CCI-006

CCI-006

T10706-50mg 50mg Ask for price
Description: CCI-006

CCI-006

T10706-5mg 5mg Ask for price
Description: CCI-006

NSC 207895 (XI-006)

A4209-10 10 mg
EUR 638.4
Description: NSC 207895 is a small-molecule inhibitor of MDMX with GI50 value of 117nM [1].NSC 207895 is a benzofuroxan derivative and is less toxic.

NSC 207895 (XI-006)

A4209-5 5 mg
EUR 367.2
Description: NSC 207895 is a small-molecule inhibitor of MDMX with GI50 value of 117nM [1].NSC 207895 is a benzofuroxan derivative and is less toxic.

NSC 207895 (XI-006)

A4209-50 50 mg
EUR 1815.6
Description: NSC 207895 is a small-molecule inhibitor of MDMX with GI50 value of 117nM [1].NSC 207895 is a benzofuroxan derivative and is less toxic.

Recombinant ASFV War-006 Protein

VAng-0978Lsx-inquire inquire Ask for price
Description: African swine fever virus (isolate Warthog/Namibia/Wart80/1980) Protein MGF 110-1L (War-006), partial, recombinant protein from E. coli. (Uniprot ID: P0C9G1)

Kinesis Inline MicrFiltr Bdy .006 thru

CHR3639 EACH
EUR 55.2

Anti-CD74 (006 (A))-VC-MMAE ADC

ADC-W-037 1mg Ask for price
Description: This ADC product is comprised of an anti-CD74 monoclonal antibody (006 (A)) conjugated via a VC linker to MMAE

Anti-CD74 (006 (A))-Mc-MMAF ADC

ADC-W-040 1mg Ask for price
Description: This ADC product is comprised of an anti-CD74 monoclonal antibody (006 (A)) conjugated via a Mc linker to MMAF

Lenti ORF particles, AKR1C3 (Myc-DDK tagged) - Human aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (AKR

RC200210L1V 200 µl Ask for price

Lenti ORF particles, AKR1C3 (Myc-DDK tagged) - Human aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (AKR

RC200210L3V 200 µl Ask for price

Recombinant ASFV BA71V-006 Protein (aa 1-83)

VAng-0741Lsx-1mg 1 mg
EUR 3490.8
Description: African swine fever virus (strain Badajoz 1971 Vero-adapted) Uncharacterized protein L83L (BA71V-006), recombinant protein from E. coli. (Uniprot ID: Q65132)

Recombinant ASFV BA71V-006 Protein (aa 1-83)

VAng-0741Lsx-500g 500 µg
EUR 2353.2
Description: African swine fever virus (strain Badajoz 1971 Vero-adapted) Uncharacterized protein L83L (BA71V-006), recombinant protein from E. coli. (Uniprot ID: Q65132)

Recombinant ASFV BA71V-006 Protein (aa 1-83)

VAng-0741Lsx-50g 50 µg
EUR 1627.2
Description: African swine fever virus (strain Badajoz 1971 Vero-adapted) Uncharacterized protein L83L (BA71V-006), recombinant protein from E. coli. (Uniprot ID: Q65132)

Recombinant ASFV Ken-006 Protein (aa 1-355)

VAng-0791Lsx-1mg 1 mg
EUR 5685.6
Description: African swine fever virus (isolate Pig/Kenya/KEN-50/1950) Protein MGF 360-3L (Ken-006), recombinant protein from E. coli. (Uniprot ID: P0C9M5)

Recombinant ASFV Ken-006 Protein (aa 1-355)

VAng-0791Lsx-500g 500 µg
EUR 3789.6
Description: African swine fever virus (isolate Pig/Kenya/KEN-50/1950) Protein MGF 360-3L (Ken-006), recombinant protein from E. coli. (Uniprot ID: P0C9M5)

Recombinant ASFV Ken-006 Protein (aa 1-355)

VAng-0791Lsx-50g 50 µg
EUR 2584.8
Description: African swine fever virus (isolate Pig/Kenya/KEN-50/1950) Protein MGF 360-3L (Ken-006), recombinant protein from E. coli. (Uniprot ID: P0C9M5)

Recombinant ASFV Mal-006 Protein (aa 20-116)

VAng-2133Lsx-1mg 1 mg
EUR 3606
Description: African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) Protein MGF 110-2L (Mal-006), recombinant protein from E. coli. (Uniprot ID: P0C9G7)

Recombinant ASFV Mal-006 Protein (aa 20-116)

VAng-2133Lsx-500g 500 µg
EUR 2419.2
Description: African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) Protein MGF 110-2L (Mal-006), recombinant protein from E. coli. (Uniprot ID: P0C9G7)

Recombinant ASFV Mal-006 Protein (aa 20-116)

VAng-2133Lsx-50g 50 µg
EUR 1677.6
Description: African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) Protein MGF 110-2L (Mal-006), recombinant protein from E. coli. (Uniprot ID: P0C9G7)

Recombinant ASFV War-006 Protein (aa 1-269)

VAng-2468Lsx-100g 100 µg
EUR 7731.6
Description: African swine fever virus (isolate Warthog/Namibia/Wart80/1980) Protein MGF 110-1L (War-006), recombinant protein. (Uniprot ID: P0C9G1)

Recombinant ASFV War-006 Protein (aa 1-269)

VAng-2468Lsx-10g 10 µg
EUR 3030
Description: African swine fever virus (isolate Warthog/Namibia/Wart80/1980) Protein MGF 110-1L (War-006), recombinant protein. (Uniprot ID: P0C9G1)

Recombinant ASFV War-006 Protein (aa 1-269)

VAng-2468Lsx-50g 50 µg
EUR 4678.8
Description: African swine fever virus (isolate Warthog/Namibia/Wart80/1980) Protein MGF 110-1L (War-006), recombinant protein. (Uniprot ID: P0C9G1)

HIV-1 Nef / BRU (171-190) mouse monoclonal antibody, clone 3A2 (01-006), Aff - Purified

AM26078PU-N 100 µg Ask for price

HIV-1 Gag Capsid protein p24 mouse monoclonal antibody, clone N13 (05-006), Aff - Purified

AM26092PU-N 100 µg Ask for price

Akr1a1/ Rat Akr1a1 ELISA Kit

ELI-49670r 96 Tests
EUR 1063.2

Akr1e2/ Rat Akr1e2 ELISA Kit

ELI-49874r 96 Tests
EUR 1063.2

AKR1B1/ Rat AKR1B1 ELISA Kit

ELA-E2220r 96 Tests
EUR 1063.2

Akr1b1/ Rat Akr1b1 ELISA Kit

ELI-07103r 96 Tests
EUR 1063.2

Akr7a3/ Rat Akr7a3 ELISA Kit

ELI-34233r 96 Tests
EUR 1063.2

Akr7a2/ Rat Akr7a2 ELISA Kit

ELI-34751r 96 Tests
EUR 1063.2

Akr1d1/ Rat Akr1d1 ELISA Kit

ELI-11627r 96 Tests
EUR 1063.2

AKR1C1 / AKR1C2 Rabbit mAb

56730 100ul
EUR 339

Akr1c18/ Rat Akr1c18 ELISA Kit

ELI-24149r 96 Tests
EUR 1063.2

Human AKR1B1 (AKR1B1) ELISA Kit

DL-AKR1B1-Hu 96T
EUR 441
Description: serum, plasma, tissue homogenates or other biological fluids.

Human AKR1B1 (AKR1B1) ELISA Kit

DLR-AKR1B1-Hu 96T
EUR 463
Description: serum, plasma, tissue homogenates or other biological fluids.

AKR7A3

enz-1129 1µg
EUR 60
Description: Recombinant Human Aldo-Keto Reductase Family 7 Member A3

AKR1C1

enz-1130 2µg
EUR 60
Description: Recombinant Human Aldo-Keto Reductase Family 1 Member C1

AKR1C3

enz-1131 2µg
EUR 60
Description: Recombinant Human Aldo-Keto Reductase Family 1 Member C3

AKR1C4

enz-1132 2µg
EUR 60
Description: Recombinant Human Aldo-Keto Reductase Family 1 Member C4

AKR1B1

enz-390 10µg
EUR 60
Description: Recombinant Human Aldose Reductase

AKR1A1

enz-464 5µg
EUR 60
Description: Recombinant Human Aldo-Keto Reductase Family 1 Member A1

AKR7A2

enz-485 5µg
EUR 60
Description: Recombinant Human Aldo-Keto Reductase Family 7 Member A2

AKR1D1

enz-931 2µg
EUR 60
Description: Recombinant Human Aldo-Keto Reductase Family 1 Member D1

AKR1C1

ant-044 5µg
EUR 60
Description: Mouse Anti Human Aldo-Keto Reductase Family 1 Member C1

AKR7A3

ant-066 5µg
EUR 60
Description: Mouse Anti Human Aldo-Keto Reductase Family 7 Member A3

AKR1B1

E8ER1903-56 100ul
EUR 275
Description: Available in various conjugation types.

AKR7A2

E8M1505-12 100ul
EUR 275
Description: Available in various conjugation types.

AKR7A2

E8R1408-3 100ul
EUR 275
Description: Available in various conjugation types.

AKR1C1

E8R1512-11 100ul
EUR 275
Description: Available in various conjugation types.

AKR1A1

CSB-CL001538HU1 10 μg plasmid + 200μl Glycerol Ask for price

AKR1A1

CSB-CL001538HU2 10 μg plasmid + 200μl Glycerol Ask for price

AKR1B1

CSB-CL001539HU1 10 μg plasmid + 200μl Glycerol Ask for price

AKR1B1

CSB-CL001539HU2 10 μg plasmid + 200μl Glycerol Ask for price

AKR1C2

CSB-CL001543HU1 10 μg plasmid + 200μl Glycerol Ask for price

AKR1C2

CSB-CL001543HU2 10 μg plasmid + 200μl Glycerol Ask for price

AKR1C3

CSB-CL001544HU1 10 μg plasmid + 200μl Glycerol Ask for price

AKR1C3

CSB-CL001544HU2 10 μg plasmid + 200μl Glycerol Ask for price

AKR1C4

CSB-CL001545HU 10 μg plasmid + 200μl Glycerol Ask for price

AKR1D1

CSB-CL001548HU 10 μg plasmid + 200μl Glycerol Ask for price

AKR7A2

CSB-CL001550HU 10 μg plasmid + 200μl Glycerol Ask for price

AKR7A3

CSB-CL001551HU1 10 μg plasmid + 200μl Glycerol Ask for price

AKR7A3

CSB-CL001551HU2 10 μg plasmid + 200μl Glycerol Ask for price

AKR7A3

CSB-CL001551HU3 10 μg plasmid + 200μl Glycerol Ask for price

AKR1D1 His

enz-098 5µg
EUR 60
Description: Recombinant Human Aldo-Keto Reductase Family 1 Member D1, His Tag

AKR1C4, His

enz-145 2µg
EUR 60
Description: Recombinant Human Aldo-Keto Reductase Family 1 Member C4, His Tag

AKR1C3, His

enz-406 5µg
EUR 60
Description: Recombinant Human Aldo-Keto Reductase Family 1 Member C3, His Tag

AKR1B10

enz-416 5µg
EUR 60
Description: Recombinant Human Aldo-Keto Reductase Family 1 Member B10

AKR7A3, His

enz-484 2µg
EUR 60
Description: Recombinant Human Aldo-Keto Reductase Family 7 Member A3, His Tag

AKR1C1, His

enz-496 5µg
EUR 60
Description: Recombinant Human Aldo-Keto Reductase Family 1 Member C1, His Tag

AKR1CL1

CSB-CL722564HU 10 μg plasmid + 200μl Glycerol Ask for price

AKR1B10

CSB-CL001540HU 10 μg plasmid + 200μl Glycerol Ask for price

Akr1b8 (untagged ORF) - Rat aldo-keto reductase family 1, member B8 (Akr1b8), (10 ug)

RN205801 10 µg Ask for price

Akr1b7 (untagged ORF) - Rat aldo-keto reductase family 1, member B7 (Akr1b7), (10 ug)

RN203308 10 µg Ask for price

AKR1E2 (untagged)-Human aldo-keto reductase family 1, member E2 (AKR1E2)

SC311005 10 µg Ask for price

Akr1e1 (GFP-tagged) - Mouse aldo-keto reductase family 1, member E1 (Akr1e1)

MG204191 10 µg Ask for price

Akr1b8 (GFP-tagged) - Mouse aldo-keto reductase family 1, member B8 (Akr1b8)

MG204542 10 µg Ask for price

Akr1c6 (GFP-tagged) - Mouse aldo-keto reductase family 1, member C6 (Akr1c6)

MG204689 10 µg Ask for price

Akr1d1 (GFP-tagged) - Mouse aldo-keto reductase family 1, member D1 (Akr1d1)

MG204723 10 µg Ask for price

AKR1E2 (GFP-tagged) - Human aldo-keto reductase family 1, member E2 (AKR1E2)

RG224970 10 µg Ask for price

Akr1c3 (untagged ORF) - Rat aldo-keto reductase family 1, member C18 (Akr1c18), (10 ug)

RN215350 10 µg Ask for price

Akr1c12 (untagged) - Rat aldo-keto reductase family 1, member C12 (Akr1c12)

RN216362 10 µg Ask for price

Akr1c2 (untagged ORF) - Rat aldo-keto reductase family 1, member C21 (Akr1c21), (10 ug)

RN201425 10 µg Ask for price

AKR1A1 siRNA

20-abx907170
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

AKR1A1 siRNA

20-abx907171
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

AKR1B1 siRNA

20-abx907174
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

AKR1B1 siRNA

20-abx907175
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

AKR1B7 siRNA

20-abx907176
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

AKR1B7 siRNA

20-abx907177
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

AKR1B8 siRNA

20-abx907178
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

AKR1C1 siRNA

20-abx907182
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

AKR1C2 siRNA

20-abx907185
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

AKR1C3 siRNA

20-abx907186
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

D Brayden works as an independent consultant for drug delivery companies.