The challenges and future of oral drug delivery: An interview with David Brayden.

David Brayden speaks to Hannah Makin, Commissioning Editor: David Brayden is a Full Professor (Advanced Drug Delivery) at the School of Veterinary Medicine, University College Dublin (UCD) and also a Fellow of the UCD Conway Institute.

Following a PhD in Pharmacology at the University of Cambridge, UK (1989), and a postdoctoral research fellowship at Stanford University, CA, USA, he set up Elan Biotechnology Research‘s in vitro pharmacology laboratory in Dublin (1991).

At Elan, he became a senior scientist and project manager of several of Elan’s joint-venture drug delivery research collaborations with US biotech companies. In 2001, he joined UCD as a lecturer in veterinary pharmacology and was appointed Associate Professor in 2006 and Full Professor in 2014.

He was a Director of the Science Foundation Ireland Research Cluster (The Irish Drug Delivery ResearchNetwork) from 2007 to 2013, is a Deputy Coordinator of an FP7 Consortium on oral peptides in nanoparticles (‘TRANS-INT’, 2012-2017), and is a Co-Principal Investigator in ‘CURAM’, Science Foundation Ireland’s new Centre for Medical Devices (2014-2020 [ 1 ]).

He was made a Fellow of the Controlled Release Society in 2012. He is the author or co-author of>>200 research publications and patents.

Aligned Nanofibers 6 Well Plate

3D00012-6 700 nm-PCLs
EUR 97

pLenti-CLDN1 shRNA-6 Plasmid

PVTBAV04867-6 2 ug
EUR 356

Mouse IL-6 Recombinant Protein

R00102-6 5ug/vial
EUR 259
Description: Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. Mouse IL-6 Recombinant Protein is purified interleukin-6 produced in yeast.

Tissue Culture Plate, 6 Well

TCP20-6 1 UNIT
EUR 53.48
  • Product category: Labware/Culture Related/Culture Plates - Multiwell

Aligned Nanofibers 6 Well Plate Inserts

3D00016-6 700 nm-PCLs
EUR 98

ExoStd? Lyophilized Exosome Standard (30 µg, Human Plasma, 6 vials)

M1040-6
EUR 1300

ExoStd? Lyophilized Exosome Standard (100 µg, Human Plasma, 6 vials)

M1041-6
EUR 1572

ExoStd? Lyophilized Exosome Standard (30 µg, Human Serum, 6 vials)

M1042-6
EUR 1300

ExoStd? Lyophilized Exosome Standard (100 µg, Human Serum, 6 vials)

M1043-6
EUR 1572

ExoStd? Lyophilized Exosome Standard (30 µg, Human Urine, 6 vials)

M1044-6
EUR 1289

ExoStd? Lyophilized Exosome Standard (100 µg, Human Urine, 6 vials)

M1045-6
EUR 1572

ExoStd? Lyophilized Exosome Standard (30 µg, Human Saliva, 6 vials)

M1046-6
EUR 1306

ExoStd? Lyophilized Exosome Standard (100 µg, Human Saliva, 6 vials)

M1047-6
EUR 1621

ExoStd? Lyophilized Exosome Standard (30 µg, U87 MG, 6 vials)

M1054-6
EUR 1306

ExoStd? Lyophilized Exosome Standard (100 µg, U87 MG, 6 vials)

M1055-6
EUR 1616

ExoStd? Lyophilized Exosome Standard (30 µg, COLO1 cell line, 6 vials)

M1048-6
EUR 1306

ExoStd? Lyophilized Exosome Standard (100 µg, COLO1 cell line, 6 vials)

M1049-6
EUR 1616

ExoStd? Lyophilized Exosome Standard (30 µg, MM1 cell line, 6 vials)

M1050-6
EUR 1306

ExoStd? Lyophilized Exosome Standard (100 µg, MM1 cell line, 6 vials)

M1051-6
EUR 1616

ExoStd? Lyophilized Exosome Standard (30 µg, BLCL21 cell line, 6 vials)

M1052-6
EUR 1306

ExoStd? Lyophilized Exosome Standard (100 µg, BLCL21 cell line, 6 vials)

M1053-6
EUR 1572

ExoStd? Lyophilized Exosome Standard (30 µg, HCT116 cell line, 6 vials)

M1058-6
EUR 1306

ExoStd? Lyophilized Exosome Standard (100 µg, HCT116 cell line, 6 vials)

M1059-6
EUR 1616

ExoStd? Lyophilized Exosome Standard (30 µg, PC3 cell line, 6 vials)

M1060-6
EUR 1306

ExoStd? Lyophilized Exosome Standard (100 µg, PC3 cell line, 6 vials)

M1061-6
EUR 1616

ExoStd? Lyophilized Exosome Standard (30 µg, DAUD1 cell line, 6 vials)

M1064-6
EUR 1306

ExoStd? Lyophilized Exosome Standard (100 µg, DAUD1 cell line, 6 vials)

M1065-6
EUR 1616

ExoStd? Lyophilized Exosome Standard (30 µg, A549 cell line, 6 vials)

M1066-6
EUR 1306

ExoStd? Lyophilized Exosome Standard (100 µg, A549 cell line, 6 vials)

M1067-6
EUR 1616

ExoStd? Lyophilized Exosome Standard (30 µg, B16F10 cell line, 6 vials)

M1070-6
EUR 1306

ExoStd? Lyophilized Exosome Standard (1090 µg, B16F10 cell line, 6 vials)

M1071-6
EUR 1616

ExoStd? Lyophilized Exosome Standard (30 µg, BPH-1 cell line, 6 vials)

M1062-6
EUR 1306

ExoStd? Lyophilized Exosome Standard (100 µg, BPH-1 cell line, 6 vials)

M1063-6
EUR 1616

ExoStd? Lyophilized Exosome Standard (30 µg, K-562 cell line, 6 vials)

M1068-6
EUR 1306

ExoStd? Lyophilized Exosome Standard (100 µg, K-562 cell line, 6 vials)

M1069-6
EUR 1616

ExoStd? Lyophilized Exosome Standard (30 µg, SK-N-SH cell line, 6 vials)

M1056-6
EUR 1306

ExoStd? Lyophilized Exosome Standard (100 µg, SK-N-SH cell line, 6 vials)

M1057-6
EUR 1616

AFP (Alpha fetoprotein) ELISA test

6 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of AFP (Alpha fetoprotein)

cDNA from Congestive Heart Failure: Heart

C1236122Hd-6 40 reactions
EUR 811
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

AlbuSorb™ Kit

A185-6 6 grams AlbuSorb™ Bead & Buffer (120 preps, 25 µl serum)
EUR 1724
Description: Albumin Removal Kit

PYREX® 6X8MM CLONING CYLINDERS

3166-6 125/pk
EUR 66
Description: Dishes; Clonig Dish/Cyl

Genomic DNA from Congestive Heart Failure: Heart, from a single donor

D1236122Hd-6 50 ug
EUR 446
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Anti-CDK1 Antibody (monoclonal, 2G11)

M00209-6 100ug/vial
EUR 334

Anti-GAPDH Antibody (monoclonal, GAPDH-71.1)

M00227-6 100ul/vial
EUR 224
Description: Mouse IgM monoclonal antibody for GAPDH detection. Tested with WB, ICC/IF in Human;Mouse;Rat;Chicken;Rabbit;Monkey;Cattle;Pig.

Anti-Vimentin Rabbit Monoclonal Antibody, Clone#RM289

M00235-6 100uL
EUR 397
Description: Anti-Vimentin Rabbit Monoclonal Antibody, Clone#RM289 tested in WB, IHC, reactive to Human

Anti-Caspase-3 Antibody (monoclonal, 8B6)

M00334-6 100ug/vial
EUR 334

Anti-Neurofilament NF-H Antibody

M05307-6 100ul
EUR 397
Description: Rabbit Polyclonal Neurofilament NF-H Antibody. Validated in IF, IHC, WB and tested in Bovine, Equine, Human, Mouse, Pig, Rat.

Anti-Dimethyl-Histone H3 (Lys36) Rabbit Monoclonal Antibody, Clone#RM141

M06819-6 100ug
EUR 462
Description: Anti-Dimethyl-Histone H3 (Lys36) Rabbit Monoclonal Antibody, Clone#RM141 tested in WB, ELISA, Multiplex, reactive to All Vertebrates

Anti-Histone H3 (mono methyl K18) Rabbit Monoclonal Antibody

M12477-6 100ug/vial
EUR 397
Description: Rabbit Monoclonal Histone H3 (mono methyl K18) Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Custom siRNA

M1253-6
EUR 457

Chemically Modified siRNA

M1254-6
EUR 474

Fluorescent labeled siRNA

M1255-6
EUR 550

ss miRNA mimics

M1259-6
EUR 452

ds miRNA mimics

M1262-6
EUR 452

miRNA Inhibitor

M1265-6
EUR 452

Anti-Acetyl-Histone H4 (Lys5) Rabbit Monoclonal Antibody, Clone#RM199

M14495-6 100ug
EUR 468
Description: Anti-Acetyl-Histone H4 (Lys5) Rabbit Monoclonal Antibody, Clone#RM199 tested in WB, ELISA, Multiplex, ICC, reactive to All Vertebrates

DiscoveryPak? HDAC Inhibitor Set

K851-6
EUR 686

DiscoveryPak? Hedgehog (Hh) Signaling Pathway Inhibitors Set

K868-6
EUR 566

DiscoveryPak? Stem Cell Fate Regulator Set IX (VC6TFZ)

K888-6
EUR 756

3D Cell Culture Gel 2ml x(soft+medium+hard)

P720SMH-6 NULL
EUR 0

Anti-Phospho-p53 (S392) Rabbit Monoclonal Antibody

P00001-6 100ug/vial
EUR 397
Description: Rabbit Monoclonal Phospho-p53 (S392) Antibody. Validated in IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Anti-Phospho-Akt (Ser473) Rabbit Monoclonal Antibody, Clone#RM251

P00024-6 100ul
EUR 385
Description: Anti-Phospho-Akt (Ser473) Rabbit Monoclonal Antibody, Clone#RM251 tested in WB, IHC, reactive to Human, (Bovine, Mouse, Rat)

Acrp30 Human, Adiponectin Human Recombinant Protein, HEK

PROTQ15848-6 Regular: 10ug
EUR 317
Description: The Acrp30 Human Recombinant produced in HEK293 cells is fused with FLAG tag.

Polystyrene Particle Size Standard

PPS-6 mL
EUR 131
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Recombinant Human Myostatin Protein

PROTO14793-6 10ug
EUR 317
Description: Myostatin is a TGF-β family member that acts as an inhibitor of skeletal muscle growth. This muscle-specific cytokine interacts with Activin type I and type II receptors, and suppresses myoblast proliferation by arresting cell-cycle in the G1 phase. Suppression of myostatin activity facilitates muscle formation and may be useful in reducing and/or preventing adiposity and type-2 diabetes. Myostatin activity can be blocked by the Activin-binding protein Follistatin, and by the propeptide of Myostatin. Recombinant Human myostatin is a 25.0 kDa protein consisting of two identical 109 amino acid polypeptides linked by a single disulfide bond.

Recombinant Human TGF-Beta 1 (HEK 293 derived) Protein

PROTP01137-6 10ug
EUR 317
Description: The three mammalian isoforms of TGF-β, TGF-β1, β2, β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. TGF-β1 is the most abundant isoform secreted by almost every cell type. It was originally identified for its ability to induce phenotypic transformation of fibroblasts and recently it has been implicated in the formation of skin tumors. Human TGF-β1 is a 25.0 kDa protein with each subunit containing 112 amino acid residues, linked by a single disulfide bond.

GLP-2 Human Glucagon Like Peptide-2 protein

PROTP01275-6 Regular: 5mg
EUR 317
Description: Glucagon Like Peptide-2 contains 34 amino acids having a molecular mass of 3922.38 Dalton.

Recombinant Human GM-CSF Protein

PROTP04141-6 20ug
EUR 317
Description: GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites.

Recombinant Human FGF-basic (154 a.a.) Protein

PROTP09038-6 50ug
EUR 317
Description: FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues.

BCL2 Human, B-Cell Lymphoma Protein 2 Alpha Human Recombinant Protein, His Tag

PROTP10415-6 Regular: 20ug
EUR 317
Description: BCL2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing amino acids 1-211 and having a molecular mass of 25.4 kDa. The BCL2 is fused to a 20 a.a. His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Recombinant Human TGF-Beta 3 (E.coli derived) Protein

PROTP10600-6 10ug
EUR 317
Description: The three mammalian isoforms of TGF-β, TGF-β1, β2, β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. The physiological role of TGF-β3 is still unknown but its expression pattern suggests a role in the regulation of certain development processes. Recombinant human TGF-β3 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.

Recombinant Human IL-7 Protein

PROTP13232-6 10ug
EUR 317
Description: IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant human IL-7 is a 17.4 kDa protein containing 153 amino acid residues.

Recombinant Human Oncostatin M (227 a.a.) Protein

PROTP13725-6 10ug
EUR 317
Description: Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSH can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells. OSM share several structural and functional characteristics with LIF, IL-6, and CNTF. Human OSM is active on murine cells. Recombinant human Oncostatin M is a 25.7 kDa protein, containing 227 amino acid residues.

Recombinant Human HGF Protein

PROTP14210-6 10ug
EUR 317
Description: HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Human HGF is expressed as a linear 697 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (α-chain and β-chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer. The α-chain consists of 463 amino acid residues and four kringle domains. The β-chain consists of 234 amino acid residues.*Manufactured using (BTI-Tn-5B1-4) cells under license from Boyce Thompson Institute for Plant Research, Inc.

VEGF Human, Vascular Endothelial Growth Factor Human Recombinant Protein, His

PROTP15692-6 Regular: 20ug
EUR 317
Description: Vascular Endothelial Growth Factor Human Recombinant produced in E.Coli is a non-glycosylated, polypeptide chain (aa 207-371) containing a total of 185 amino acids and having a molecular mass of 21.3 kDa (corresponding to Isoform L-VEGF165 UniProt acc#P15692-11). ;The VEGF is fused to a 20 a.a His-tag at N-terminus and is purified by proprietary chromatographic techniques.

FLT1 Human, Vascular Endothelial Growth Factor receptor-1 Human Recombinant Protein, His Tag

PROTP17948-6 Regular: 10ug
EUR 317
Description: FLT1 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 298 amino acids fragment (31-328) corresponding to the IgG like domains 1-3 from the mature soluble FLT1 protein, having a total molecular mass of 43kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. ;The FLT1 His is purified by proprietary chromatographic techniques.

SNCA Alpha Synuclein 96-140 Human Recombinant Protein

PROTP37840-6 Regular: 50ug
EUR 317
Description: A-Synuclein 96-140 Human Recombinant which is a deletion mutant of the a-synuclein amino acids 96-140, produced in E.Coli is a single, non-glycosylated polypeptide chain of 46 amino acids having a molecular mass of 5.2kDa, with an additional Met attached at the N-terminus. The Recombinant Human a-Synuclein 96-140 is purified by proprietary chromatographic techniques.

SPA-Cys Staphylococcal Protein-A Cys Long Form Recombinant Protein

PROTP38507-6 Regular: 100mg
EUR 418
Description: SPA-Cys long Recombinant produced in E.Coli is a single non-glycosylated polypeptide chain with a Cys on C-terminus. SPA-Cys is comprised of 5 IgG-binding domains E-D-A-B-C aligned in series containing 423 amino acids and having a molecular mass of 46.7kDa containing little or no carbohydrate.

Recombinant Human SDF-1 Beta (CXCL12) Protein

PROTP48061-6 10ug
EUR 317
Description: SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant human SDF-1β is an 8.5 kDa protein containing 72 amino acid residues.

Recombinant Human PlGF-3 Protein

PROTP49763-6 25ug
EUR 317
Description: PlGF-3 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-3 is expressed exclusively in the placenta. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. PlGF-3 lacks heparin binding affinity. Recombinant human PlGF-3 is a 45.7 kDa disulfide-linked homodimeric protein of two 203 amino acid polypeptide chains.

Total Protein from Congestive Heart Failure: Heart

P1236122Hd-6 1 mg
EUR 461
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Rev-CEM-Luc HIV Reporter Cells

HRC-6 NULL
EUR 0

Alkaline Phosphate Buffer, 10x

K2191050-6 50 ml
EUR 137
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

PhosphoSeek? Phosphoprotein Purification Kit

K1401-6
EUR 958

PhosphoSeek? Phosphoprotein Enrichment Kit

K1402-6
EUR 784

ExoPure? Maxi Chromatography Columns

K1248-6
EUR 1409

Feline TNF alpha Recombinant Protein

R00002-6 5ug/vial
EUR 259
Description: Tumor necrosis factor alpha (TNFSF2, TNF alpha) is a member of the TNF Superfamily. TNF alpha, being an endogenous pyrogen, is able to induce fever, to induce apoptotic cell death, to induce sepsis (through IL-1 & IL-6 production), to induce cachexia, induce inflammation, and to inhibit tumorigenesis and viral replication. Feline TNF alpha Recombinant Protein is purified TNF alpha (TNFSF2) produced in yeast.

Rabbit VEGF-A Recombinant Protein

R00045-6 5ug/vial
EUR 259
Description: VEGF-A is member of the family of vascular endothelial growth factor (VEGF) proteins, which stimulate vasculogenesis and angiogenesis to restore oxygen supply to tissues. VEGF-A is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor (VPF). Rabbit VEGF-A Recombinant Protein is purified vascular endothelial growth factor A produced in yeast.

Human IL-1 beta Recombinant Protein

R00101-6 5ug/vial
EUR 259
Description: IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Human IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast.

Mouse IL-4 Recombinant Protein

R00230-6 5ug/vial
EUR 259
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Mouse IL-4 Recombinant Protein is purified interleukin-4 produced in yeast.

Ovine CXCL10 Recombinant Protein

R00278-6 5ug/vial
EUR 259
Description: The ELR-negative CXC chemokine CXCL10 (IP-10) has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. Ovine CXCL10 Recombinant Protein is purified CXCL10 (IP-10) produced in yeast.

Mouse IL-2 Recombinant Protein

R00387-6 5ug/vial
EUR 259
Description: Interleukin-2 (IL-2) is a cytokine produced by T-helper cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial to the regulation of the immune response. Mouse IL-2 Recombinant Protein is purified interleukin-2 produced in yeast.

Feline IFN gamma Recombinant Protein

R00393-6 5ug/vial
EUR 259
Description: IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Feline IFN gamma Recombinant Protein is purified IFN gamma produced in yeast.

Rabbit IL-17A Recombinant Protein

R00421-6 5ug/vial
EUR 259
Description: IL-17A is a member of the IL-17 family of cytokines, whose members are involved in numerous immune regulatory functions. IL-17 induces the production of many other cytokines, chemokines, and prostaglandins. Rabbit IL-17A Recombinant Protein is purified interleukin-17A produced in yeast.

Feline IL-8 Recombinant Protein

R00423-6 5ug/vial
EUR 259
Description: Interleukin-8 (IL-8), also known as CXCL8, is an ELR-positive CXC family member chemokine produced by macrophages and other cell types such as epithelial cells. ELR-positive CXC chemokines such as IL-8 specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. Feline IL-8 Recombinant Protein is purified interleukin-8 produced in yeast.

Rat CCL4 Recombinant Protein

R00703-6 5ug/vial
EUR 259
Description: The small chemotactic cytokine CCL4 (MIP-1 beta) is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is involved in several inflammatory and autoimmune diseases including viral infection such as HIV-1/AIDS. Rat CCL4 Recombinant Protein is purified chemokine ligand 4 (CCL4, MIP-1 beta) produced in yeast.

Rabbit GM-CSF Recombinant Protein

R00911-6 5ug/vial
EUR 259
Description: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a protein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts. GM-CSF stimulates stem cells to produce granulocytes and monocytes and is glycosylated in its mature form.

Rabbit IL-1 alpha Recombinant Protein

R01144-6 5ug/vial
EUR 259
Description: IL-1 alpha (IL-1α, IL-1F1) is a member of the interleukin 1 family of cytokines. IL-1 alpha is an inflammatory cytokine active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. Rabbit IL-1 alpha Recombinant Protein is purified interleukin-1 alpha cytokine produced in yeast.

Swine CXCL9 Recombinant Protein

R01397-6 5ug/vial
EUR 259
Description: CXCL9 (MIG) is a T-cell chemoattractant. Induced by IFN-gamma (IFN-γ), the ELR-negative chemokine CXCL9 (MIG) elicits its effects by binding to the cell surface chemokine receptor CXCR3. Swine CXCL9 Recombinant Protein is purified CXCL9 (MIG) produced in yeast.

Paraffin Tissue Section - Human Brain Tumor: Epndymoma

T2235035-6 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

D Brayden serves on the Editorial Advisory Boards of Drug Discovery Today, European Journal of Pharmaceutical Sciences, Advanced Drug Delivery Reviews and the Journal of Veterinary Pharmacology and Therapeutics, and is an Associate Editor of Therapeutic Delivery. D Brayden works as an independent consultant for drug delivery companies.